Search Results - "Shukr, Marwa"
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In vitro and in vivo evaluation of self-nanoemulsifying drug delivery systems of cilostazol for oral and parenteral administration
Published in International journal of pharmaceutics (10-12-2014)“…[Display omitted] The current investigation was aimed to improve the solubility of poorly soluble drug, cilostazol (CLZ). Self-nanoemulsifying drug delivery…”
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Gastroretentive Cosolvent-Based In Situ Gel as a Promising Approach for Simultaneous Extended Delivery and Enhanced Bioavailability of Mitiglinide Calcium
Published in Journal of pharmaceutical sciences (01-02-2019)“…Ion cross-linking in situ gels are novel liquid sustained-release drug delivery systems. These systems are unsuitable for poorly water-soluble drugs such as…”
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Formulation, in vitro and in vivo evaluation of lidocaine HCl ocular inserts for topical ocular anesthesia
Published in Archives of pharmacal research (01-07-2014)“…Topical anesthesia is a safe and cost-effective method considered as the first-choice in many procedures. The objective of the present study was to develop…”
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Spanlastics nanovesicular ocular insert as a novel ocular delivery of travoprost: optimization using Box-Behnken design and in vivo evaluation
Published in Journal of liposome research (02-10-2022)“…Currently, travoprost is a synthetic prostaglandin F 2 α analogue used in the treatment of glaucoma, it is delivered by eye drop solution. Due to its very low…”
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Formulation, in vitro and in vivo evaluation of lidocaine HCl ocular inserts for topical ocular anesthesia
Published in Archives of pharmacal research (2014)“…Topical anesthesia is a safe and cost-effective method considered as the first-choice in many procedures. The objective of the present study was to develop…”
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Amisulpride–CD-Loaded Liposomes: Optimization and In Vivo Evaluation
Published in AAPS PharmSciTech (01-08-2018)“…Amisulpride (AMS) is an atypical antipsychotic agent used for the treatment of schizophrenia. The effect of different variables, i.e., the type of…”
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Evaluation of Topical Gel Bases Formulated with Various Essential Oils for Antibacterial Activity against Methicillin-Resistant Staphylococcus Aureus
Published in Tropical journal of pharmaceutical research (01-12-2013)“…Purpose: To formulate topical gels containing various essential oils and evaluate their antibacterial activity against methicillin-resistant Staphylococcus…”
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Formulation and optimization of duloxetine hydrochloride buccal films: in vitro and in vivo evaluation
Published in Drug delivery (2017)“…Duloxetine hydrochloride (DH) is a serotonin-norepinephrine reuptake inhibitor (SSNRI) indicated for the treatment of depression. Duloxetine suffers from…”
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Development and optimization of novel controlled-release pioglitazone provesicular powders using 32 factorial design
Published in Drug delivery and translational research (01-02-2015)“…This work aimed at studying a novel controlled drug delivery proniosomal formulation of pioglitazone for treatment of diabetes type-2. The effects of…”
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An in vitro and in vivo comparative study of directly compressed solid dispersions and freeze dried sildenafil citrate sublingual tablets for management of pulmonary arterial hypertension
Published in Acta pharmaceutica (Zagreb, Croatia) (01-09-2012)“…Sildenafilcitrate (SILD) orodispersable sublingual tablets (ODSTs) have been developed using two comparative techniques for improving their oral…”
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Novel in situ gelling ocular inserts for voriconazole-loaded niosomes: design, in vitro characterisation and in vivo evaluation of the ocular irritation and drug pharmacokinetics
Published in Journal of microencapsulation (02-01-2016)“…This work aimed to develop voriconazole in situ gelling ocular inserts loaded with niosomal suspension. Niosomes and mixed niosomes were prepared using span 40…”
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Development and optimization of ezetimibe nanoparticles with improved antihyperlipidemic activity
Published in Journal of drug delivery science and technology (01-02-2019)“…The current study aims to develop and optimize ezetimibe chitosan nanoparticles by using 22.31 factorial design, where chitosan: tripolyphosphate (TPP) ratio…”
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Design and evaluation of mucoadhesive in situ liposomal gel for sustained ocular delivery of travoprost using two steps factorial design
Published in Journal of drug delivery science and technology (01-02-2021)“…Travoprost (TRAVO) is a prostaglandin analog used to reduce the intraocular pressure (IOP) for patients suffering from glaucoma and ocular hypertension. The…”
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Brain targeting of agomelatine egg lecithin based chitosan coated nanoemulsion
Published in Pharmaceutical development and technology (21-04-2021)“…Intranasal drug delivery system has been proposed as an alternative delivery system to target agomelatine (AGO) to the brain and improving its bioavailability…”
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Sucrose acetate isobutyrate based nanovesicles: A promising platform for drug delivery and bioavailability enhancement
Published in Journal of drug delivery science and technology (01-08-2020)“…Sucrose acetate isobutyrate based nanovesicles (SBN) were designed to enhance the Ticagrelor poor bioavailability (36%). SBN were formulated with different…”
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Gastroretentive Microsponge as a Promising Tool for Prolonging the Release of Mitiglinide Calcium in Type-2 Diabetes Mellitus: Optimization and Pharmacokinetics Study
Published in AAPS PharmSciTech (01-08-2018)“…Diabetes mellitus is one of the leading causes of death due to the persistent hyperglycemia that leads to potential complications. Lack of patients’ adherence…”
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Optimization and in vivo evaluation of duloxetine hydrochloride buccoadhesive lyophilized tablets
Published in Journal of drug delivery science and technology (01-08-2019)“…Duloxetine hydrochloride (DH) is a serotonin-norepinephrine reuptake inhibitor (SSNRI) indicated for the treatment of depression. Duloxetine suffers from…”
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Development and optimization of novel controlled-release pioglitazone provesicular powders using 3² factorial design
Published in Drug delivery and translational research (01-02-2015)“…This work aimed at studying a novel controlled drug delivery proniosomal formulation of pioglitazone for treatment of diabetes type-2. The effects of…”
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Komparativna in vitro i in vivo studija sublingvalnih tableta dobivenih izravnom kompresijom čvrstih disperzija i liofiliziranog sildenafil citrata za terapiju plućne arterijske hipertenzije
Published in Acta Pharmaceutica (30-09-2012)“…U radu je opisan razvoj sublingvalnih tableta sildenafil citrata (SILD) raspršivih u ustima (ODST) za terapiju plućne arterijske hipertenzije (PAH), sa svrhom…”
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