Search Results - "Shuker, Suzanne B"

Discovering High-Affinity Ligands for Proteins: SAR by NMR by Shuker, Suzanne B., Hajduk, Philip J., Meadows, Robert P., Fesik, Stephen W.

“…A nuclear magnetic resonance (NMR)-based method is described in which small organic molecules that bind to proximal subsites of a protein are identified,…”
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Structure of Bcl-x-Bak peptide complex: recognition between regulators of apoptosis by Sattler, Michael, Nettesheim, David, Meadows, Robert P, Harlan, John E, Eberstadt, Matthias, Yoon, Ho Sup, Shuker, Suzanne B, Chang, Brian S, Minn, Andy J, Thompson, Craig B, Fesik, Stephen W

“…Heterodimerization between members of the Bcl-2 family of proteins is a key event in the regulation of programmed cell death. The molecular basis for…”
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NMR-Based Modification of Matrix Metalloproteinase Inhibitors with Improved Bioavailability by Hajduk, Philip J, Shuker, Suzanne B, Nettesheim, David G, Craig, Richard, Augeri, David J, Betebenner, David, Albert, Daniel H, Guo, Yan, Meadows, Robert P, Xu, Lianhong, Michaelides, Michael, Davidsen, Steven K, Fesik, Stephen W

“…The NMR-based discovery of biaryl hydroxamate inhibitors of the matrix metalloproteinase stromelysin (MMP-3) has been previously described (Hajduk et al. J…”
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Heterodimerization Studies of Calix[4]arene Derivatives in Polar Solvents by Sasine, Joshua S, Brewster, R. Elizabeth, Caran, Kevin L, Bentley, Adrienne M, Shuker, Suzanne B

“…Several calix[4]arene derivatives propylated on the lower rim and substituted on the upper rim with amino or carboxyl groups have been synthesized. Examples…”
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Expression, purification, and refolding of mouse islet neogenesis associated protein-related protein for NMR studies by Kulis, Michael D., Shuker, Suzanne B.

“…Islet neogenesis associated protein-related protein (INGAPrP) is thought to be involved in the differentiation of non-insulin-producing cells to…”
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Structural basis for IL-4 receptor phosphopeptide recognition by thelRS-1 PTB domain by Zhou, Ming-Ming, Huang, Baohua, Olejniczak, Edward T, Meadows, Robert P, Shuker, Suzanne B, Miyazaki, Masaya, Trüb, Thomas, Shoelson, Steven E, Fesik, Stephen W

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The 10 C-terminal residues of HTLV-I protease are not necessary for enzymatic activity by Herger, Bryan E., Mariani, Victoria L., Dennison, Kelly J., Shuker, Suzanne B.

“…Sequence alignment of human T-lymphotropic virus type I (HTLV-I) protease and other retroviral proteases reveals that the leukemia virus proteases contain…”
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Structure of Bcl-xL-Bak peptide complex : Recognition between regulators of apoptosis by SATTLER, M, LIANG, H, THOMPSON, C. B, FESIK, S. W, NETTESHEIM, D, MEADOWS, R. P, HARLAN, J. E, EBERSTADT, M, HO SUP YOON, SHUKER, S. B, CHANG, B. S, MINN, A. J

“…Heterodimerization between members of the Bcl-2 family of proteins is a key event in the regulation of programmed cell death. The molecular basis for…”
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Structural basis for IL-4 receptor phosphopeptide recognition by the IRS-1 PTB domain by Zhou, M M, Huang, B, Olejniczak, E T, Meadows, R P, Shuker, S B, Miyazaki, M, Trüb, T, Shoelson, S E, Fesik, S W

“…We present the NMR structure of the PTB domain of insulin receptor substrate-1 (IRS-1) complexed to a tyrosine-phosphorylated peptide derived from the IL-4…”
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Structure of BcI-X$_L$-Bak Peptide Complex: Recognition between Regulators of Apoptosis by Sattler, Michael, Liang, Heng, Nettesheim, David, Meadows, Robert P., Harlan, John E., Eberstadt, Matthias, Yoon, Ho Sup, Shuker, Suzanne B., Chang, Brian S., Minn, Andy J., Thompson, Craig B., Fesik, Stephen W.

“…Heterodimerization between members of the Bcl-2 family of proteins is a key event in the regulation of programmed cell death. The molecular basis for…”
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Structure of Bcl-x L -Bak Peptide Complex: Recognition Between Regulators of Apoptosis by Sattler, Michael, Liang, Heng, Nettesheim, David, Meadows, Robert P., Harlan, John E., Eberstadt, Matthias, Yoon, Ho Sup, Shuker, Suzanne B., Chang, Brian S., Minn, Andy J., Thompson, Craig B., Fesik, Stephen W.

“…Heterodimerization between members of the Bcl-2 family of proteins is a key event in the regulation of programmed cell death. The molecular basis for…”
Get full text