Search Results - "Shuker, D.E.G."

The effect of haem in red and processed meat on the endogenous formation of N-nitroso compounds in the upper gastrointestinal tract by Lunn, J.C., Kuhnle, G., Mai, V., Frankenfeld, C., Shuker, D.E.G., Glen, R. C., Goodman, J.M., Pollock, J.R.A., Bingham, S.A.

“…Red and processed meat (PM) consumption increases the risk of large bowel cancer and it has been demonstrated that haem in red meat (RM) stimulates the…”
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Deleterious effects of a cafeteria diet on the livers of nonobese rats by MacQueen, Hilary A, Sadler, Dawn A, Moore, Sharon A, Daya, Sandeep, Brown, Jacqueline Y, Shuker, David E.G, Seaman, Michael, Wassif, Wassif S

“…Abstract Rats were fed from weaning on 1 of 3 diets. Those fed a cafeteria diet had livers that were enlarged and abnormal by visual inspection. The rats…”
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Acetaldehyde-haemoglobin adducts as markers of alcohol exposure in man by Farmer, P.B., Conduah Birt, J.E.E., Shuker, D.E.G.

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Development of a quantitative method for the analysis of 3-nitrotyrosine in small amounts of proteins by Herce-Pagliai, C., Kotecha, S., Shuker, D.E.G.

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The Effect of n-6 Polyunsaturated Fatty Acid on Blood Levels of Malondialdehyde-Deoxyguanosine Adducts in Human Subjects by Moore, S.A., Humphreys, E., Friesen, M.D., Shuker, D.E.G., Bingham, S.A.

“…The role of n -6 polyunsaturated fats upon the formation of the mutagenic DNA adduct malondialdehydedeoxyguanosine (M 1 dG) in blood was investigated in male…”
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Detection of malondialdehyde — Deoxy guanosine in human tissues in relation to diet by Leuratta, C., Singh, R., Bingham, S., Plastaras, J.P., Marnett, J.L., Shuker, D.E.G.

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Quantification of 7-methyldeoxyguanosine using immunoaffinity purification and HPLC with electrochemical detection by Bianchini, F, Montesano, R, Shuker, D E, Cuzick, J, Wild, C P

“…7-Methylguanine (7-meG) could be a useful marker of recent past exposure to environmental methylating agents for use in epidemiological studies. A method is…”
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Immunoaffinity purification and gas chromatography-mass spectrometric quantification of 3-alkyladenines in urine: metabolism studies and basal excretion levels in man by Prevost, V, Shuker, D E, Friesen, M D, Eberle, G, Rajewsky, M F, Bartsch, H

“…Immunoaffinity gels were prepared by coupling monoclonal antibody (Mab) EM-6-47 to protein A-Sepharose, and were used to make small columns retaining…”
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Biomonitoring human exposure to environmental carcinogenic chemicals by Farmer, P.B., Sepai, O., Lawrence, R., Autrup, H., Nielsen, P.Sabro, Vestergård, A.B., Waters, R., Leuratti, C., Jones, N.J., Stone, J., Baan, R.A., van Delft, J.H.M., Steenwinkel, M.J.S.T., Kyrtopoulos, S.A., Souliotis, V.L., Theodorakopoulos, N., Bacalis, N.C., Natarajan, A.T., Tates, A.D., Haugen, A., Andreassen, Å., Øvrebø, S., Shuker, D.E.G., Amaning, K.S., Schouft, A., Ellul, A., Garner, R.C., Dingley, K.H., Abbondandolo, A., Merlo, F., Cole, J., Aldrich, K., Beare, D., Capulas, E., Rowley, G., Waugh, A.P.W., Povey, A.C., Haque, K., Kirsch-Volders, M., Van Hummelen, P., Castelain, P

“…A coordinated study was carried out on the development, evaluation and application of biomonitoring procedures for populations exposed to environmental…”
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Urinary excretion of S-benzylmercapturic acid as an indicator of N-nitroso-N-methylbenzylamine exposure by Lin, D X, Friesen, M, Malaveille, C, Shuker, D E, Bartsch, H

“…The excretion of S-benzylmercapturic acid (SBzMA) in the urine of rats treated with N-nitroso-N-methylbenzylamine (NMBzA) was determined by gas…”
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Effects of a high fat diet on liver DNA methylation in rats exposed to N-nitrosodimethylamine by Camus, A M, Béréziat, J C, Shuker, D E, Hietanen, E, Wild, C P, Montesano, R, Bartsch, H

“…Previous experiments have shown that a high fat diet changes incidence and tumour sites by N-nitroso-dialkylamines. The purpose of this study was to examine…”
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Interaction of [14C]dimethylnitrosamine with albumin produced by rat hepatocytes in culture by Seago, A, Shuker, D E, Paine, A J

“…Rat hepatocyte cultures were incubated with [14C]dimethylnitrosamine (14C-NDMA) and the utility of measuring covalent binding of the radiolabel to newly…”
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Mutagenicity to Salmonella, Drosophila and the mouse bone marrow of the human antineoplastic agent fotemustine: prediction of carcinogenic potency by Ashby, J, Vogel, E W, Tinwell, H, Callander, R D, Shuker, D E

“…The antineoplastic agent fotemustine is shown to be a base-pair mutagen to Salmonella. Activity is more marked in the uvrB-proficient strain G46 than in the…”
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