Search Results - "Shuhong Shen"

Analysis of error profiles in deep next-generation sequencing data by Ma, Xiaotu, Shao, Ying, Tian, Liqing, Flasch, Diane A, Mulder, Heather L, Edmonson, Michael N, Liu, Yu, Chen, Xiang, Newman, Scott, Nakitandwe, Joy, Li, Yongjin, Li, Benshang, Shen, Shuhong, Wang, Zhaoming, Shurtleff, Sheila, Robison, Leslie L, Levy, Shawn, Easton, John, Zhang, Jinghui

“…Sequencing errors are key confounding factors for detecting low-frequency genetic variants that are important for cancer molecular diagnosis, treatment, and…”
Get full text

Distinct genomic landscape of Chinese pediatric acute myeloid leukemia impacts clinical risk classification by Liu, Ting, Rao, Jianan, Hu, Wenting, Cui, Bowen, Cai, Jiaoyang, Liu, Yuhan, Sun, Huiying, Chen, Xiaoxiao, Tang, Yanjing, Chen, Jing, Wang, Xiang, Wang, Han, Qian, Wubin, Mao, Binchen, Guo, Sheng, Wang, Ronghua, Liu, Yu, Shen, Shuhong

“…Studies have revealed key genomic aberrations in pediatric acute myeloid leukemia (AML) based on Western populations. It is unknown to what extent the current…”
Get full text

Therapy-induced mutations drive the genomic landscape of relapsed acute lymphoblastic leukemia by Li, Benshang, Brady, Samuel W., Ma, Xiaotu, Shen, Shuhong, Zhang, Yingchi, Li, Yongjin, Szlachta, Karol, Dong, Li, Liu, Yu, Yang, Fan, Wang, Ningling, Flasch, Diane A., Myers, Matthew A., Mulder, Heather L., Ding, Lixia, Liu, Yanling, Tian, Liqing, Hagiwara, Kohei, Xu, Ke, Zhou, Xin, Sioson, Edgar, Wang, Tianyi, Yang, Liu, Zhao, Jie, Zhang, Hui, Shao, Ying, Sun, Hongye, Sun, Lele, Cai, Jiaoyang, Sun, Hui-Ying, Lin, Ting-Nien, Du, Lijuan, Li, Hui, Rusch, Michael, Edmonson, Michael N., Easton, John, Zhu, Xiaofan, Zhang, Jingliao, Cheng, Cheng, Raphael, Benjamin J., Tang, Jingyan, Downing, James R., Alexandrov, Ludmil B., Zhou, Bin-Bing S., Pui, Ching-Hon, Yang, Jun J., Zhang, Jinghui

“…To study the mechanisms of relapse in acute lymphoblastic leukemia (ALL), we performed whole-genome sequencing of 103 diagnosis-relapse-germline trios and…”
Get full text

c-Myc alone is enough to reprogram fibroblasts into functional macrophages by Li, Shanshan, Chen, Guoyu, Huang, Xia, Zhang, Yingwen, Shen, Shuhong, Feng, Haizhong, Li, Yanxin

“…Macrophage-based cell therapy is promising in solid tumors, but the efficient acquisition of macrophages remains a challenge. Induced pluripotent stem cell…”
Get full text

Negative feedback–defective PRPS1 mutants drive thiopurine resistance in relapsed childhood ALL by Li, Benshang, Li, Hui, Bai, Yun, Kirschner-Schwabe, Renate, Yang, Jun J, Chen, Yao, Lu, Gang, Tzoneva, Gannie, Ma, Xiaotu, Wu, Tongmin, Li, Wenjing, Lu, Haisong, Ding, Lixia, Liang, Huanhuan, Huang, Xiaohang, Yang, Minjun, Jin, Lei, Kang, Hui, Chen, Shuting, Du, Alicia, Shen, Shuhong, Ding, Jianping, Chen, Hongzhuan, Chen, Jing, von Stackelberg, Arend, Gu, Longjun, Zhang, Jinghui, Ferrando, Adolfo, Tang, Jingyan, Wang, Shengyue, Zhou, Bin-Bing S

“…The authors uncover new mutations in an enzyme from the purine synthesis pathway that cause resistance to leukemia therapy, and reveal a new mechanism by which…”
Get full text

Restoring MLL reactivates latent tumor suppression-mediated vulnerability to proteasome inhibitors by Ge, Maolin, Li, Dan, Qiao, Zhi, Sun, Yan, Kang, Ting, Zhu, Shouhai, Wang, Shifen, Xiao, Hua, Zhao, Chunjun, Shen, Shuhong, Xu, Zhenshu, Liu, Han

“…MLL undergoes multiple distinct chromosomal translocations to yield aggressive leukemia with dismal outcomes. Besides their well-established role in…”
Get full text

Small genomic insertions form enhancers that misregulate oncogenes by Abraham, Brian J., Hnisz, Denes, Weintraub, Abraham S., Kwiatkowski, Nicholas, Li, Charles H., Li, Zhaodong, Weichert-Leahey, Nina, Rahman, Sunniyat, Liu, Yu, Etchin, Julia, Li, Benshang, Shen, Shuhong, Lee, Tong Ihn, Zhang, Jinghui, Look, A. Thomas, Mansour, Marc R., Young, Richard A.

“…The non-coding regions of tumour cell genomes harbour a considerable fraction of total DNA sequence variation, but the functional contribution of these…”
Get full text

ARHGEF12 regulates erythropoiesis and is involved in erythroid regeneration after chemotherapy in acute lymphoblastic leukemia patients by Xie, Yangyang, Gao, Li, Xu, Chunhui, Chu, Liming, Gao, Lei, Wu, Ruichi, Liu, Yu, Liu, Ting, Sun, Xiao-Jian, Ren, Ruibao, Tang, Jingyan, Zheng, Yi, Zhou, Yong, Shen, Shuhong

“…Hematopoiesis is a finely regulated process in vertebrates under both homeostatic and stress conditions. By whole exome sequencing, we studied the genomics of…”
Get full text

Psychosocial outcomes in Chinese survivors of pediatric cancers or bone marrow failure disorders: A single-center study by Jiaoyang Cai, Yin Ting Cheung, Phillip Lung Wai Au-Doung, Wenting Hu, Yijin Gao, Hua Zhang, Mingjing Ji, Shuhong Shen, Jing Chen, Jingyan Tang

“…Background/objectivesMost of the studies on functional outcomes in pediatric survivors of cancers and bone marrow failure disorders have been conducted in…”
Get full text

Psychosocial outcomes in Chinese survivors of pediatric cancers or bone marrow failure disorders: A single-center study by Cai, Jiaoyang, Cheung, Yin Ting, Au-Doung, Phillip Lung Wai, Hu, Wenting, Gao, Yijin, Zhang, Hua, Ji, Mingjing, Shen, Shuhong, Chen, Jing, Tang, Jingyan

“…Most of the studies on functional outcomes in pediatric survivors of cancers and bone marrow failure disorders have been conducted in North American, European,…”
Get full text

Chromatin accessibility landscape of relapsed pediatric B-lineage acute lymphoblastic leukemia by Wang, Han, Sun, Huiying, Liang, Bilin, Zhang, Fang, Yang, Fan, Cui, Bowen, Ding, Lixia, Wang, Xiang, Wang, Ronghua, Cai, Jiaoyang, Tang, Yanjing, Rao, Jianan, Hu, Wenting, Zhao, Shuang, Wu, Wenyan, Chen, Xiaoxiao, Wu, Kefei, Lai, Junchen, Xie, Yangyang, Li, Benshang, Tang, Jingyan, Shen, Shuhong, Liu, Yu

“…For around half of the pediatric B-lineage acute lymphoblastic leukemia (B-ALL) patients, the molecular mechanism of relapse remains unclear. To fill this gap…”
Get full text

Heterogeneous cytogenetic subgroups and outcomes in childhood acute megakaryoblastic leukemia: a retrospective international study by Inaba, Hiroto, Zhou, Yinmei, Abla, Oussama, Adachi, Souichi, Auvrignon, Anne, Beverloo, H. Berna, de Bont, Eveline, Chang, Tai-Tsung, Creutzig, Ursula, Dworzak, Michael, Elitzur, Sarah, Fynn, Alcira, Forestier, Erik, Hasle, Henrik, Liang, Der-Cherng, Lee, Vincent, Locatelli, Franco, Masetti, Riccardo, De Moerloose, Barbara, Reinhardt, Dirk, Rodriguez, Laura, Van Roy, Nadine, Shen, Shuhong, Taga, Takashi, Tomizawa, Daisuke, Yeoh, Allen E.J., Zimmermann, Martin, Raimondi, Susana C.

“…Comprehensive clinical studies of patients with acute megakaryoblastic leukemia (AMKL) are lacking. We performed an international retrospective study on 490…”
Get full text

Multistep networks for roll force prediction in hot strip rolling mill by Shen, Shuhong, Guye, Denzel, Ma, Xiaoping, Yue, Stephen, Armanfard, Narges

“…Hot rolling processes consist of multiple single rolling stand operating at high temperature and speed to achieve desired steel shapes and superior properties,…”
Get full text

Whole transcriptome sequencing reveals a TCF4-ZNF384 fusion in acute lymphoblastic leukemia by Wu, Zhengyu, Zhang, Fang, Liu, Chengzhu, Shen, Shuhong, Chu, Jinhua, Yang, Linhai, Xie, Zhiwei, Liu, Yu, Liu, Kangkang, Wang, Ningling

“…Previous studies have shown that, the clinical features and prognosis of ZNF384-rearranged pediatric acute lymphoblastic leukemia (ALL) depend on its…”
Get full text

CD9 shapes glucocorticoid sensitivity in pediatric B-cell precursor acute lymphoblastic leukemia by Zhang, Chi, Chan, Kathy Yuen Yee, Ng, Wing Hei, Cheung, John Tak Kit, Sun, Qiwei, Wang, Han, Chung, Po Yee, Cheng, Frankie Wai Tsoi, Leung, Alex Wing Kwan, Zhang, Xiao-Bing, Lee, Po Yi, Fok, Siu Ping, Lin, Guanglan, Poon, Ellen Ngar Yun, Feng, Jian-Hua, Tang, Yan-Lai, Luo, Xue-Qun, Huang, Li-Bin, Kang, Wei, Tang, Patrick Ming Kuen, Huang, Junbin, Chen, Chun, Dong, Junchao, Mejstrikova, Ester, Cai, Jiaoyang, Liu, Yu, Shen, Shuhong, Yang, Jun J, Yuen, Patrick Man Pan, Li, Chi Kong, Leung, Kam Tong

“…Resistance to glucocorticoids (GC), the common agents for remission induction in pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL), poses a…”
Get full text

Development and Evaluation of a Leukemia Diagnosis System Using Deep Learning in Real Clinical Scenarios by Zhou, Min, Wu, Kefei, Yu, Lisha, Xu, Mengdi, Yang, Junjun, Shen, Qing, Liu, Bo, Shi, Lei, Wu, Shuang, Dong, Bin, Wang, Hansong, Yuan, Jiajun, Shen, Shuhong, Zhao, Liebin

“…Leukemia is the most common malignancy affecting children. The morphologic analysis of bone marrow smears is an important initial step for diagnosis. Recent…”
Get full text

Safety and Effectiveness of Rasburicase in the Control of Hyperuricemia in Pediatric Patients with Non-Hodgkin’s Lymphoma and Acute Leukemia: An Open-Label, Single-Arm, Multi-center, Interventional Study by Wang, Tianyou, Zhu, Xiaofan, Chen, Yumei, Shen, Shuhong, Tang, Yongmin, Zhang, Jingying, He, Yingyi, Zhang, Hui, Gao, Ju, Fang, Jianpei, Liu, Rong, Wu, Xiaoyan, Sun, Jinchuan, Zhang, Minlu

“…Introduction Despite rasburicase's proven efficiency in Caucasians, Japanese, and Koreans, studies evaluating the safety and effectiveness of rasburicase in…”
Get full text

Correction: Targeting ARHGEF12 promotes neuroblastoma differentiation, MYCN degradation, and reduces tumorigenicity by Yang, Yi, Wang, Siqi, Cai, Jiaoyang, Liang, Jianwei, Zhang, Yingwen, Xie, Yangyang, Luo, Fei, Tang, Jingyan, Gao, Yijin, Shen, Shuhong, Feng, Haizhong, Li, Yanxin

Get full text

Targeting ARHGEF12 promotes neuroblastoma differentiation, MYCN degradation, and reduces tumorigenicity by Yang, Yi, Wang, Siqi, Cai, Jiaoyang, Liang, Jianwei, Zhang, Yingwen, Xie, Yangyang, Luo, Fei, Tang, Jingyan, Gao, Yijin, Shen, Shuhong, Feng, Haizhong, Li, Yanxin

“…Purpose Neuroblastoma arises from developmental block of embryonic neural crest cells and is one of the most common and deadly pediatric tumors. However, the…”
Get full text

Destabilization of AETFC through C/EBPα-mediated repression of LYL1 contributes to t(8;21) leukemic cell differentiation by Zhang, Meng-Meng, Liu, Na, Zhang, Yuan-Liang, Rong, Bowen, Wang, Xiao-Lin, Xu, Chun-Hui, Xie, Yin-Yin, Shen, Shuhong, Zhu, Jiang, Nimer, Stephen D., Chen, Zhu, Chen, Sai-Juan, Roeder, Robert G., Lan, Fei, Wang, Lan, Huang, Qiu-Hua, Sun, Xiao-Jian

Get full text