Search Results - "Shubina, Maria"

Drivers of the Sex Disparity in Statin Therapy in Patients with Coronary Artery Disease: A Cohort Study by Zhang, Huabing, Plutzky, Jorge, Shubina, Maria, Turchin, Alexander

“…Women are less likely to be prescribed statins than men. Existing reports explain only a fraction of this difference. We conducted a study to identify factors…”
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RIPK3‐driven cell death during virus infections by Upton, Jason W., Shubina, Maria, Balachandran, Siddharth

“…The programmed self‐destruction of infected cells is a powerful antimicrobial strategy in metazoans. For decades, apoptosis represented the dominant mechanism…”
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Hypoglycemia and Clinical Outcomes in Patients With Diabetes Hospitalized in the General Ward by Turchin, Alexander, Matheny, Michael E, Shubina, Maria, Scanlon, James V, Greenwood, Bonnie, Pendergrass, Merri L

“…OBJECTIVE: Hypoglycemia is associated with adverse outcomes in mixed populations of patients in intensive care units. It is not known whether the same risks…”
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Proliferation, cancer, and aging—novel functions of the nucleolar methyltransferase fibrillarin? by Shubina, Maria Y., Musinova, Yana R., Sheval, Eugene V.

“…Fibrillarin is an essential nucleolar protein that catalyzes the 2′‐O‐methylation of ribosomal RNAs. Recently, experimental data have begun to accumulate that…”
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Molecular Coevolution of Nuclear and Nucleolar Localization Signals inside the Basic Domain of HIV-1 Tat by Kurnaeva, Margarita A, Zalevsky, Arthur O, Arifulin, Eugene A, Lisitsyna, Olga M, Tvorogova, Anna V, Shubina, Maria Y, Bourenkov, Gleb P, Tikhomirova, Maria A, Potashnikova, Daria M, Kachalova, Anastasia I, Musinova, Yana R, Golovin, Andrey V, Vassetzky, Yegor S, Sheval, Eugene V

“…During evolution, viruses had to adapt to an increasingly complex environment of eukaryotic cells. Viral proteins that need to enter the cell nucleus or…”
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Origin of the nuclear proteome on the basis of pre-existing nuclear localization signals in prokaryotic proteins by Lisitsyna, Olga M, Kurnaeva, Margarita A, Arifulin, Eugene A, Shubina, Maria Y, Musinova, Yana R, Mironov, Andrey A, Sheval, Eugene V

“…The origin of the selective nuclear protein import machinery, which consists of nuclear pore complexes and adaptor molecules interacting with the nuclear…”
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Switching of cardiac troponin I between nuclear and cytoplasmic localization during muscle differentiation by Kharitonov, Alexey V., Shubina, Maria Y., Nosov, Georgii A., Mamontova, Anastasia V., Arifulin, Eugene A., Lisitsyna, Olga M., Nalobin, Denis S., Musinova, Yana R., Sheval, Eugene V.

“…The nuclear accumulation of proteins may depend on the presence of short targeting sequences, which are known as nuclear localization signals (NLSs). Here, we…”
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EXIST: EXamining rIsk of excesS adiposiTy—Machine learning to predict obesity‐related complications by Turchin, Alexander, Morrison, Fritha J., Shubina, Maria, Lipkovich, Ilya, Shinde, Shraddha, Ahmad, Nadia N., Kan, Hong

“…Background Obesity is associated with an increased risk of multiple conditions, ranging from heart disease to cancer. However, there are few predictive models…”
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The GAR domain integrates functions that are necessary for the proper localization of fibrillarin (FBL) inside eukaryotic cells by Shubina, Maria Y, Arifulin, Eugene A, Sorokin, Dmitry V, Sosina, Mariya A, Tikhomirova, Maria A, Serebryakova, Marina V, Smirnova, Tatiana, Sokolov, Svyatoslav S, Musinova, Yana R, Sheval, Eugene V

“…Fibrillarin (FBL) is an essential nucleolar protein that participates in pre-rRNA methylation and processing. The methyltransferase domain of FBL is an example…”
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Biodegradable polymeric microspheres and nanospheres for drug delivery in the peritoneum by Kohane, Daniel S., Tse, Julie Y., Yeo, Yoon, Padera, Robert, Shubina, Maria, Langer, Robert

“…Drug delivery to the peritoneum is hampered by rapid clearance, and could be improved by application of controlled release technology. We investigated the…”
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Some exact solutions of Friedmann cosmological equation by Shubina, Maria

“…In this paper we present a number of examples of exact solutions for the Friedmann cosmological equation for metric F(R) gravity model. Emphasis was placed on…”
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Exact analytical vacuum solutions of Rn-gravity model depending on two variables by Shubina, Maria

“…In this paper we consider the metric power-law f(R)∼Rn-gravity model for the four-dimensional metric tensor depending on two coordinates. We obtain exact…”
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Exact analytical vacuum solutions of R n -gravity model depending on two variables by Shubina, Maria

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Risk factors for lack of statin therapy in patients with diabetes and coronary artery disease by Zhang, Huabing, MD, Plutzky, Jorge, MD, Shubina, Maria, ScD, Turchin, Alexander, MD, MS

“…Background Patients with both diabetes and coronary artery disease (CAD) have exceedingly high cardiovascular risk. Nevertheless, little is known about…”
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Discontinuation of statins in routine care settings by Zhang, Huabing, Plutzky, Jorge, Skentzos, Stephen, Morrison, Fritha, Mar, Perry, Shubina, Maria, Turchin, Alexander

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Reasons for discontinuing insulin and factors associated with insulin discontinuation in patients with type 2 diabetes mellitus: a real-world evidence study by Wu, Jianmin, Morrison, Fritha, Zhao, Zhenxiang, Haynes, Ginger, He, Xuanyao, Ali, Ayad K, Shubina, Maria, Malmasi, Shervin, Ge, Wendong, Peng, Xiaomei, Turchin, Alexander

“…Evidence suggests that insulin therapy of patients with type 2 diabetes mellitus (T2DM) is frequently discontinued. However, the reasons for discontinuing…”
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Relationship of Physician Volume With Process Measures and Outcomes in Diabetes by Turchin, Alexander, Shubina, Maria, Pendergrass, Merri L

“…OBJECTIVE:--The volume of patients cared for by an individual physician (physician volume) has been linked to improved outcomes for a number of conditions. It…”
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"Summary Page": a novel tool that reduces omitted data in research databases by Goldberg, Saveli I, Niemierko, Andrzej, Shubina, Maria, Turchin, Alexander

“…Data entry errors are common in clinical research databases. Omitted data are of particular concern because they are more common than erroneously inserted data…”
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Prevalence and factors affecting home blood pressure documentation in routine clinical care: a retrospective study by Kramer, Michael H, Breydo, Eugene, Shubina, Maria, Babcock, Kelly, Einbinder, Jonathan S, Turchin, Alexander

“…Home blood pressure (BP) is closely linked to patient outcomes. However, the prevalence of its documentation has not been examined. The objective of this study…”
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Continued Statin Prescriptions After Adverse Reactions and Patient Outcomes: A Cohort Study by Zhang, Huabing, Plutzky, Jorge, Shubina, Maria, Turchin, Alexander

“…Many patients discontinue statin treatment, often after having a possible adverse reaction. The risks and benefits of continued statin therapy after an adverse…”
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