Search Results - "Shu, Shan"

Exploring the role of soundscape in restorative experience: A pilot study from children's perspective by Shu, Shan

“…Indoor and outdoor noise is renowned for its ability to negatively affect children's health and performance. However, the possible restorative benefits of…”
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Recent examples of α-ketoglutarate-dependent mononuclear non-haem iron enzymes in natural product biosyntheses by Gao, Shu-Shan, Naowarojna, Nathchar, Cheng, Ronghai, Liu, Xueting, Liu, Pinghua

“…Covering: up to 2018 α-Ketoglutarate (αKG, also known as 2-oxoglutarate)-dependent mononuclear non-haem iron (αKG-NHFe) enzymes catalyze a wide range of…”
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Substrate relay in an Hsp70‐cochaperone cascade safeguards tail‐anchored membrane protein targeting by Cho, Hyunju, Shan, Shu‐ou

“…Membrane proteins are aggregation‐prone in aqueous environments, and their biogenesis poses acute challenges to cellular protein homeostasis. How the chaperone…”
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Guiding tail-anchored membrane proteins to the endoplasmic reticulum in a chaperone cascade by Shan, Shu-ou

“…Newly synthesized integral membrane proteins must traverse the aqueous cytosolic environment before arrival at their membrane destination and are prone to…”
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Tuning an Imine Reductase for the Asymmetric Synthesis of Azacycloalkylamines by Concise Structure‐Guided Engineering by Zhang, Jun, Liao, Daohong, Chen, Rongchang, Zhu, Fangfang, Ma, Yaqing, Gao, Lei, Qu, Ge, Cui, Chengsen, Sun, Zhoutong, Lei, Xiaoguang, Gao, Shu‐Shan

“…Although imine reductases (IREDs) are emerging as attractive reductive aminases (RedAms), their substrate scope is still narrow, and rational engineering is…”
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Role of Hsp70 in Post-Translational Protein Targeting: Tail-Anchored Membrane Proteins and Beyond by Shan, Shu-Ou

“…The Hsp70 family of molecular chaperones acts as a central 'hub' in the cell that interacts with numerous newly synthesized proteins to assist in their…”
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Mechanisms of Tail-Anchored Membrane Protein Targeting and Insertion by Chio, Un Seng, Cho, Hyunju, Shan, Shu-ou

“…Proper localization of membrane proteins is essential for the function of biological membranes and for the establishment of organelle identity within a cell…”
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ATPase and GTPase Tangos Drive Intracellular Protein Transport by Shan, Shu-ou

“…The GTPase superfamily of proteins provides molecular switches to regulate numerous cellular processes. The ‘GTPase switch’ paradigm, in which external…”
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Signal recognition particle: an essential protein-targeting machine by Akopian, David, Shen, Kuang, Zhang, Xin, Shan, Shu-ou

“…The signal recognition particle (SRP) and its receptor compose a universally conserved and essential cellular machinery that couples the synthesis of nascent…”
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A ribosome-associated chaperone enables substrate triage in a cotranslational protein targeting complex by Hsieh, Hao-Hsuan, Lee, Jae Ho, Chandrasekar, Sowmya, Shan, Shu-ou

“…Protein biogenesis is essential in all cells and initiates when a nascent polypeptide emerges from the ribosome exit tunnel, where multiple ribosome-associated…”
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Targeting NQO1/GPX4-mediated ferroptosis by plumbagin suppresses in vitro and in vivo glioma growth by Zhan, Sheng, Lu, Li, Pan, Shu-shan, Wei, Xiao-qian, Miao, Rong-rong, Liu, Xiao-hui, Xue, Ming, Lin, Xiu-kun, Xu, Huan-li

“…Background Ferroptosis has attracted increasing interest in cancer therapy. Emerging evidences suggest that naturally occurring naphthoquinones exhibit potent…”
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Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting by Jomaa, Ahmad, Gamerdinger, Martin, Hsieh, Hao-Hsuan, Wallisch, Annalena, Chandrasekaran, Viswanathan, Ulusoy, Zeynel, Scaiola, Alain, Hegde, Ramanujan S, Shan, Shu-Ou, Ban, Nenad, Deuerling, Elke

“…The nascent polypeptide-associated complex (NAC) interacts with newly synthesized proteins at the ribosomal tunnel exit and competes with the signal…”
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Structure-guided semi-rational design of an imine reductase for enantio-complementary synthesis of pyrrolidinamine by Zhang, Jun, Ma, Yaqing, Zhu, Fangfang, Bao, Jinping, Wu, Qiaqing, Gao, Shu-Shan, Cui, Chengsen

“…In this study, engineered imine reductases (IREDs) of IRED M5, originally from Actinoalloteichus hymeniacidonis , were obtained through structure-guided…”
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Influence of Rashba spin–orbit interaction on the effective mass of bound polaron in an anisotropic quantum dot by Shan, Shu-Ping

“…The effective mass of bound polaron in an anisotropic quantum dot is calculated by using improved linear combination operator method. Under the influence of…”
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Ribosome profiling reveals multiple roles of SecA in cotranslational protein export by Zhu, Zikun, Wang, Shuai, Shan, Shu-ou

“…SecA, an ATPase known to posttranslationally translocate secretory proteins across the bacterial plasma membrane, also binds ribosomes, but the role of SecA’s…”
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An ankyrin repeat chaperone targets toxic oligomers during amyloidogenesis by Gupta, Arpit, Lu, Chuqi, Wang, Feng, Chou, Tsui‐Fen, Shan, Shu‐ou

“…Numerous age‐linked diseases are rooted in protein misfolding; this has motivated the development of small molecules and therapeutic antibodies that target the…”
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Fidelity of Cotranslational Protein Targeting to the Endoplasmic Reticulum by Hsieh, Hao-Hsuan, Shan, Shu-Ou

“…Fidelity of protein targeting is essential for the proper biogenesis and functioning of organelles. Unlike replication, transcription and translation…”
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Fidelity of Cotranslational Protein Targeting by the Signal Recognition Particle by Zhang, Xin, Shan, Shu-ou

“…Accurate folding, assembly, localization, and maturation of newly synthesized proteins are essential to all cells and require high fidelity in the protein…”
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Short-term electricity load time series prediction by machine learning model via feature selection and parameter optimization using hybrid cooperation search algorithm by Niu, Wen-jing, Feng, Zhong-kai, Li, Shu-shan, Wu, Hui-jun, Wang, Jia-yang

“…Abstract Reliable load time series forecasting plays an important role in guaranteeing the safe and stable operation of modern power system. Due to the…”
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Co-translational protein targeting to the bacterial membrane by Saraogi, Ishu, Shan, Shu-ou

“…Co-translational protein targeting by the Signal Recognition Particle (SRP) is an essential cellular pathway that couples the synthesis of nascent proteins to…”
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