Search Results - "Shu, Qian"

Facile pretreatment of lignocellulosic biomass using deep eutectic solvents by Zhang, Cheng-Wu, Xia, Shu-Qian, Ma, Pei-Sheng

“…[Display omitted] •Three kinds of DESs used in the pretreatment of corncob.•Improved delignification and enzymatic hydrolysis efficiency.•Removal of lignin and…”
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Dynamic m(6)A mRNA methylation directs translational control of heat shock response by Zhou, Jun, Wan, Ji, Gao, Xiangwei, Zhang, Xingqian, Jaffrey, Samie R, Qian, Shu-Bing

“…The most abundant mRNA post-transcriptional modification is N(6)-methyladenosine (m(6)A), which has broad roles in RNA biology. In mammalian cells, the…”
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Translational reprogramming in cellular stress response by Liu, Botao, Qian, Shu-Bing

“…Cell survival in changing environments requires appropriate regulation of gene expression, including translational control. Multiple stress signaling pathways…”
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mTORC1 couples cyst(e)ine availability with GPX4 protein synthesis and ferroptosis regulation by Zhang, Yilei, Swanda, Robert V., Nie, Litong, Liu, Xiaoguang, Wang, Chao, Lee, Hyemin, Lei, Guang, Mao, Chao, Koppula, Pranavi, Cheng, Weijie, Zhang, Jie, Xiao, Zhenna, Zhuang, Li, Fang, Bingliang, Chen, Junjie, Qian, Shu-Bing, Gan, Boyi

“…Glutathione peroxidase 4 (GPX4) utilizes glutathione (GSH) to detoxify lipid peroxidation and plays an essential role in inhibiting ferroptosis. As a…”
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Therapeutic mRNA Engineering from Head to Tail by Jia, Longfei, Qian, Shu-Bing

“…Conspectus Synthetic messenger RNA (mRNA), once delivered into cells, can be readily translated into proteins by ribosomes, which do not distinguish exogenous…”
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Decoding mRNA translatability and stability from the 5′ UTR by Jia, Longfei, Mao, Yuanhui, Ji, Quanquan, Dersh, Devin, Yewdell, Jonathan W., Qian, Shu-Bing

“…Precise control of protein synthesis by engineering sequence elements in 5′ untranslated regions (5′ UTRs) remains a fundamental challenge. To accelerate our…”
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Cotranslational Response to Proteotoxic Stress by Elongation Pausing of Ribosomes by Liu, Botao, Han, Yan, Qian, Shu-Bing

“…Translational control permits cells to respond swiftly to a changing environment. Rapid attenuation of global protein synthesis under stress conditions has…”
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Hijacking host ribosomes via tRNA mimicry by Uematsu, Saori, Qian, Shu-Bing

“…The bacterial pathogen Legionella pneumophila uses effectors — toxins — to facilitate pathogenesis within host cells. A recent study identifies dual mechanisms…”
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Making sense of mRNA translational “noise” by Mao, Yuanhui, Qian, Shu-Bing

“…The importance of translation fidelity has been apparent since the discovery of genetic code. It is commonly believed that translation deviating from the main…”
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Global mapping of translation initiation sites in mammalian cells at single-nucleotide resolution by Lee, Sooncheol, Liu, Botao, Lee, Soohyun, Huang, Sheng-Xiong, Shen, Ben, Qian, Shu-Bing

“…Understanding translational control in gene expression relies on precise and comprehensive determination of translation initiation sites (TIS) across the…”
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Long non-coding RNA TUG1 is up-regulated in hepatocellular carcinoma and promotes cell growth and apoptosis by epigenetically silencing of KLF2 by Huang, Ming-De, Chen, Wen-Ming, Qi, Fu-Zhen, Sun, Ming, Xu, Tong-Peng, Ma, Pei, Shu, Yong-Qian

“…Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death worldwide, and the biology of this cancer remains poorly understood. Recent…”
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A Rhenium Isonitrile Complex Induces Unfolded Protein Response‐Mediated Apoptosis in Cancer Cells by King, A. Paden, Marker, Sierra C., Swanda, Robert V., Woods, Joshua J., Qian, Shu‐Bing, Wilson, Justin J.

“…Complexes of the element Re have recently been shown to possess promising anticancer activity through mechanisms of action that are distinct from the…”
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Exploring Ovarian Cancer Cell Resistance to Rhenium Anticancer Complexes by Marker, Sierra C., King, A. Paden, Swanda, Robert V., Vaughn, Brett, Boros, Eszter, Qian, Shu‐Bing, Wilson, Justin J.

“…Rhenium tricarbonyl complexes have been recently investigated as novel anticancer agents. However, little is understood about their mechanisms of action, as…”
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TISdb: a database for alternative translation initiation in mammalian cells by Wan, Ji, Qian, Shu-Bing

“…Proper selection of the translation initiation site (TIS) on mRNAs is crucial for the production of desired protein products. Recent studies using ribosome…”
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Quantitative profiling of initiating ribosomes in vivo by Gao, Xiangwei, Wan, Ji, Liu, Botao, Ma, Ming, Shen, Ben, Qian, Shu-Bing

“…QTI-seq (quantitative translation initiation sequencing) maps the position of the start codon and thus allows the determination of initiation efficiency in…”
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Ganoderic acid hinders renal fibrosis via suppressing the TGF-β/Smad and MAPK signaling pathways by Geng, Xiao-qiang, Ma, Ang, He, Jin-zhao, Wang, Liang, Jia, Ying-li, Shao, Guang-ying, Li, Min, Zhou, Hong, Lin, Shu-qian, Ran, Jian-hua, Yang, Bao-xue

“…Renal fibrosis is considered as the pathway of almost all kinds of chronic kidney diseases (CKD) to the end stage of renal diseases (ESRD). Ganoderic acid (GA)…”
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Decoding Human Cytomegalovirus by Stern-Ginossar, Noam, Weisburd, Ben, Michalski, Annette, Le, Vu Thuy Khanh, Hein, Marco Y., Huang, Sheng-Xiong, Ma, Ming, Shen, Ben, Qian, Shu-Bing, Hengel, Hartmut, Mann, Matthias, Ingolia, Nicholas T., Weissman, Jonathan S.

“…The human cytomegalovirus (HCMV) genome was sequenced 20 years ago. However, like those of other complex viruses, our understanding of its protein coding…”
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Dynamic eIF3a O-GlcNAcylation controls translation reinitiation during nutrient stress by Shu, Xin Erica, Mao, Yuanhui, Jia, Longfei, Qian, Shu-Bing

“…In eukaryotic cells, many messenger RNAs (mRNAs) possess upstream open reading frames (uORFs) in addition to the main coding region. After uORF translation,…”
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A Versatile eIF3d in Translational Control of Stress Adaptation by Jia, Longfei, Qian, Shu-Bing

“…Lamper et al. (2020) reported that eIF3d-mediated cap-dependent translation is subject to regulation by phosphorylation during chronic glucose deprivation,…”
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Do betel quid and areca nut chewing deteriorate prognosis of oral cancer? A systematic review, meta‐analysis, and research agenda by Yang, Jun, Wang, Zi‐Yu, Huang, Long, Yu, Tao‐Lin, Wan, Shu‐Qian, Song, Juan, Zhang, Bing‐Liang, Hu, Ming

“…Objective To explore the correlations between the habit of betel quid and areca nut (BQ‐AN) chewing and the prognosis of oral cancer (OC). Methods We performed…”
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