Search Results - "Shreve, Jacob"
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Impact of heart failure on reoperation in adult congenital heart disease: An innovative machine learning model
Published in The Journal of thoracic and cardiovascular surgery (01-06-2024)“…The study objectives were to evaluate the association between preoperative heart failure and reoperative cardiac surgical outcomes in adult congenital heart…”
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Machine learning integrates genomic signatures for subclassification beyond primary and secondary acute myeloid leukemia
Published in Blood (11-11-2021)“…Although genomic alterations drive the pathogenesis of acute myeloid leukemia (AML), traditional classifications are largely based on morphology, and…”
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Identification of a plastidial phenylalanine exporter that influences flux distribution through the phenylalanine biosynthetic network
Published in Nature communications (10-09-2015)“…In addition to proteins, L -phenylalanine is a versatile precursor for thousands of plant metabolites. Production of phenylalanine-derived compounds is a…”
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Tranexamic Acid for Trauma Resuscitation in the United States of America
Published in Seminars in thrombosis and hemostasis (01-03-2017)“…The utilization of tranexamic acid (TXA) for the management of bleeding trauma patients has been a subject of much debate on both sides of the Atlantic and in…”
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The Evolving Landscape of Myelodysplastic Syndrome Prognostication
Published in Clinical hematology international (2020)“…Myelodysplastic syndromes (MDSs) are potentially devastating monoclonal deviations of hematopoiesis that lead to bone marrow dysplasia and variable cytopenias…”
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Rapid genome assembly and comparison decode intrastrain variation in human alphaherpesviruses
Published in mBio (31-03-2015)“…Herpes simplex virus (HSV) is a widespread pathogen that causes epithelial lesions with recurrent disease that manifests over a lifetime. The lifelong aspect…”
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Metatranscriptomic profiles of Eastern subterranean termites, Reticulitermes flavipes (Kollar) fed on second generation feedstocks
Published in BMC genomics (22-04-2015)“…Second generation lignocellulosic feedstocks are being considered as an alternative to first generation biofuels that are derived from grain starches and…”
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Artificial Intelligence in Oncology: Current Capabilities, Future Opportunities, and Ethical Considerations
Published in American Society of Clinical Oncology educational book (01-04-2022)“…The promise of highly personalized oncology care using artificial intelligence (AI) technologies has been forecasted since the emergence of the field…”
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Modulation of nonessential amino acid biosynthetic pathways in virulent Hessian fly larvae (Mayetiola destructor), feeding on susceptible host wheat (Triticum aestivum)
Published in Journal of insect physiology (01-02-2018)“…[Display omitted] •Annotated 16 genes for nonessential amino acids (NAA) biosynthesis in Hessian fly.•Feeding larvae display 3 transcript profiles for NAA…”
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Genetic Determinants for Enzymatic Digestion of Lignocellulosic Biomass Are Independent of Those for Lignin Abundance in a Maize Recombinant Inbred Population
Published in Plant physiology (Bethesda) (01-08-2014)“…Biotechnological approaches to reduce or modify lignin in biomass crops are predicated on the assumption that it is the principal determinant of the…”
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Viral forensic genomics reveals the relatedness of classic herpes simplex virus strains KOS, KOS63, and KOS79
Published in Virology (New York, N.Y.) (01-05-2016)“…Abstract Herpes simplex virus 1 (HSV−1) is a widespread global pathogen, of which the strain KOS is one of the most extensively studied. Previous sequence…”
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Expression profiles of cell-wall related genes vary broadly between two common maize inbreds during stem development
Published in BMC genomics (29-10-2019)“…The cellular machinery for cell wall synthesis and metabolism is encoded by members of large multi-gene families. Maize is both a genetic model for grass…”
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1265 Single-institution retrospective review of patient’s diagnosed with immune checkpoint inhibitor therapy-related pneumonitis
Published in Journal for immunotherapy of cancer (01-11-2023)“…BackgroundImmune checkpoint inhibitor therapy-related (ICI) pneumonitis poses a significant challenge in patients with cancer. There is paucity of data on…”
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1266 Utilizing predictive modeling to risk stratify patients to low versus high grade immune checkpoint inhibitor therapy-related pneumonitis
Published in Journal for immunotherapy of cancer (01-11-2023)“…BackgroundImmune checkpoint inhibitor therapy-related (ICI) pneumonitis is a potential serious complication for patients with cancer. We have previously shown…”
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A Massive Expansion of Effector Genes Underlies Gall-Formation in the Wheat Pest Mayetiola destructor
Published in Current biology (02-03-2015)“…Gall-forming arthropods are highly specialized herbivores that, in combination with their hosts, produce extended phenotypes with unique morphologies [1]. Many…”
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P921: ARTIFICIAL INTELLIGENCE BASED FDG PET/CT RADIOMICS FOR RISK STRATIFICATION IN NEWLY DIAGNOSED MULTIPLE MYELOMA
Published in HemaSphere (08-08-2023)Get full text
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P812: PREDICTING HIGH‐RISK DISEASE BIOLOGY USING ARTIFICIAL INTELLIGENCE BASED FDG PET/CT RADIOMICS IN NEWLY DIAGNOSED MULTIPLE MYELOMA
Published in HemaSphere (08-08-2023)Get full text
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A machine learning model of response to hypomethylating agents in myelodysplastic syndromes
Published in iScience (21-10-2022)“…Hypomethylating agents (HMA) prolong survival and improve cytopenias in individuals with higher-risk myelodysplastic syndrome (MDS). Only 30-40% of patients,…”
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Genome Sequence of the Virulent Model Herpes Simplex Virus 1 Strain McKrae Demonstrates the Presence of at Least Two Widely Used Variant Strains
Published in Microbiology resource announcements (25-03-2021)“…Herpes simplex virus 1 (HSV-1) strain McKrae was isolated in 1965 and has been utilized by many laboratories. Three HSV-1 strain McKrae stocks have been…”
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