Search Results - "Shrestha, Tej B."
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Copper resistance is essential for virulence of Mycobacterium tuberculosis
Published in Proceedings of the National Academy of Sciences - PNAS (25-01-2011)“…Copper (Cu) is essential for many biological processes, but is toxic when present in excessive amounts. In this study, we provide evidence that Cu plays a…”
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2
System for delivering microwave ablation to subcutaneous tumors in small-animals under high-field MRI thermometry guidance
Published in International journal of hyperthermia (31-12-2022)“…Bio-effects following thermal treatments are a function of the achieved temperature profile in tissue, which can be estimated across tumor volumes with…”
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An integrated platform for small-animal hyperthermia investigations under ultra-high-field MRI guidance
Published in International journal of hyperthermia (01-06-2018)“…Integrating small-animal experimental hyperthermia instrumentation with magnetic resonance imaging (MRI) affords real-time monitoring of spatial temperature…”
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4
Copper-Boosting Compounds: a Novel Concept for Antimycobacterial Drug Discovery
Published in Antimicrobial Agents and Chemotherapy (01-02-2013)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Cell Based Drug Delivery: Micrococcus luteus Loaded Neutrophils as Chlorhexidine Delivery Vehicles in a Mouse Model of Liver Abscesses in Cattle
Published in PloS one (26-05-2015)“…The recent WHO report on antibiotic resistances shows a dramatic increase of microbial resistance against antibiotics. With only a few new antibiotics in the…”
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6
Luminol-based bioluminescence imaging of mouse mammary tumors
Published in Journal of photochemistry and photobiology. B, Biology (05-10-2013)“…[Display omitted] •Luminol can be used to track neutrophil invasion of tumors.•For the first time, we have shown Luminol can be used to image solid carcinomas…”
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7
Peptide nanosponges designed for rapid uptake by leukocytes and neural stem cells
Published in RSC advances (01-01-2018)“…The structure of novel binary nanosponges consisting of (cholesterol-(K/D) DEVDGC) -trimaleimide units possessing a trigonal maleimide linker, to which either…”
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8
A Nanobiosensor for the Detection of Arginase Activity
Published in Nanomedicine (01-02-2017)“…Abstract A nanobiosensor for arginase detection was designed and synthesized. It features a central dopamine-coated iron/iron oxide nanoparticle to which…”
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9
Designing a Cleavable Cell Surface Protein for Cytotherapy and Drug Delivery Applications
Published in Applied sciences (01-03-2021)“…Many cytotherapy applications focus on delivering a therapeutic molecule or nanoparticle to a disease site. One challenging step in this delivery is releasing…”
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Extracellular vesicles production and proteomic cargo varies with incubation time and temperature
Published in Experimental cell research (15-01-2023)“…Extracellular vesicles (EVs) are heterogenous populations of proteolipid bi-layered vesicles secreted by cells as an important biological process. EVs cargo…”
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11
Magnetic-Fe/Fe3O4-nanoparticle-bound SN38 as carboxylesterase-cleavable prodrug for the delivery to tumors within monocytes/macrophages
Published in Beilstein journal of nanotechnology (13-06-2012)“…The targeted delivery of therapeutics to the tumor site is highly desirable in cancer treatment, because it is capable of minimizing collateral damage. Herein,…”
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12
Carbon dioxide hydrogenation to aromatic hydrocarbons by using an iron/iron oxide nanocatalyst
Published in Beilstein journal of nanotechnology (02-06-2014)“…The quest for renewable and cleaner energy sources to meet the rapid population and economic growth is more urgent than ever before. Being the most abundant…”
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13
Synergy of Iron Chelators and Therapeutic Peptide Sequences Delivered via a Magnetic Nanocarrier
Published in Journal of functional biomaterials (26-06-2017)“…Here, we report the synthesis, characterization, and efficacy study of Fe/Fe₃O₄-nanoparticles that were co-labeled with a tumor-homing and membrane-disrupting…”
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14
Increased volumes of lobule VI in a valproic acid model of autism are associated with worse set-shifting performance in male Long-Evan rats
Published in Brain research (15-08-2021)“…[Display omitted] •VPA male rats had larger lobule VI volume compared to control males.•Valproic acid (VPA) female rats had smaller volumes across lobules of…”
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15
Protease-Sensitive, Polymer-Caged Liposomes: A Method for Making Highly Targeted Liposomes Using Triggered Release
Published in ACS nano (22-03-2011)“…Liposomes have become useful and well-known drug delivery vehicles because of their ability to entrap drugs without chemically modifying them and to deliver…”
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In Vitro and In Vivo Metabolism of the Radiolytic Compound 2-Dodecylcyclobutanone
Published in Journal of food science (01-05-2010)“…Our knowledge about the metabolism of alkylcyclobutanones (2-ACBs) is limited, and the lack of literature on the metabolism of 2-ACBs causes consumers to doubt…”
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Using Naturally Occurring Bioluminescent Enzymes to Track Specific Cell Populations
Published in Methods in molecular biology (Clifton, N.J.) (2020)“…Luminol-based bioluminescence imaging allows noninvasive tracking of oxidatively active cells such as neutrophils. Luminol is given intravenously or…”
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18
Enhanced charge separation in TiO2/nanocarbon hybrid photocatalysts through coupling with short carbon nanotubes
Published in RSC advances (31-03-2021)“…The interfacial contact between TiO2 and graphitic carbon in a hybrid composite plays a critical role in electron transfer behavior, and in turn, its…”
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Thermosensitive Liposomes for Gemcitabine Delivery to Pancreatic Ductal Adenocarcinoma
Published in Cancers (01-09-2024)“…Treatment of pancreatic ductal adenocarcinoma with gemcitabine is limited by an increased desmoplasia, poor vascularization, and short plasma half-life…”
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Nanoscopic surfactant behavior of the porin MspA in aqueous media
Published in Beilstein journal of nanotechnology (25-04-2013)“…The mycobacterial porin MspA is one of the most stable channel proteins known to date. MspA forms vesicles at low concentrations in aqueous buffers. Evidence…”
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