Search Results - "Shrestha, Prerana"

Cell-type-specific drug-inducible protein synthesis inhibition demonstrates that memory consolidation requires rapid neuronal translation by Shrestha, Prerana, Ayata, Pinar, Herrero-Vidal, Pedro, Longo, Francesco, Gastone, Alexandra, LeDoux, Joseph E., Heintz, Nathaniel, Klann, Eric

“…New protein synthesis is known to be required for the consolidation of memories, yet existing methods of blocking translation lack spatiotemporal precision and…”
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Layer 2/3 pyramidal cells in the medial prefrontal cortex moderate stress induced depressive behaviors by Shrestha, Prerana, Mousa, Awni, Heintz, Nathaniel

“…Major depressive disorder (MDD) is a prevalent illness that can be precipitated by acute or chronic stress. Studies of patients with Wolfram syndrome and…”
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Application of a Translational Profiling Approach for the Comparative Analysis of CNS Cell Types by Doyle, Joseph P., Dougherty, Joseph D., Heiman, Myriam, Schmidt, Eric F., Stevens, Tanya R., Ma, Guojun, Bupp, Sujata, Shrestha, Prerana, Shah, Rajiv D., Doughty, Martin L., Gong, Shiaoching, Greengard, Paul, Heintz, Nathaniel

“…Comparative analysis can provide important insights into complex biological systems. As demonstrated in the accompanying paper, translating ribosome affinity…”
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The modulation of emotional and social behaviors by oxytocin signaling in limbic network by Triana-Del Rio, Rodrigo, Ranade, Sayali, Guardado, Jahel, LeDoux, Joseph, Klann, Eric, Shrestha, Prerana

“…Neuropeptides can exert volume modulation in neuronal networks, which account for a well-calibrated and fine-tuned regulation that depends on the sensory and…”
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Spatiotemporally resolved protein synthesis as a molecular framework for memory consolidation by Shrestha, Prerana, Klann, Eric

“…De novo protein synthesis is required for long-term memory consolidation. Dynamic regulation of protein synthesis occurs via a complex interplay of translation…”
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Alzheimer's disease: Lost memories found by Shrestha, Prerana, Klann, Eric

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Lost memories found by Shrestha, Prerana, Klann, Eric

“…Enhancing synaptic connections between neurons in the brain's hippocampus that are normally activated during memory formation rescues memory deficits in a…”
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Amygdala inhibitory neurons as loci for translation in emotional memories by Shrestha, Prerana, Shan, Zhe, Mamcarz, Maggie, Ruiz, Karen San Agustin, Zerihoun, Adam T., Juan, Chien-Yu, Herrero-Vidal, Pedro M., Pelletier, Jerry, Heintz, Nathaniel, Klann, Eric

“…To survive in a dynamic environment, animals need to identify and appropriately respond to stimuli that signal danger 1 . Survival also depends on suppressing…”
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Mutational Analysis of Vibrio fischeri c-di-GMP-Modulating Genes Reveals Complex Regulation of Motility by Shrestha, Prerana, Razvi, Ali, Fung, Brittany L, Eichinger, Steven J, Visick, Karen L

“…The symbiont Vibrio fischeri uses motility to colonize its host. In numerous bacterial species, motility is negatively controlled by cyclic-di-GMP (c-di-GMP),…”
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An AAV-CRISPR/Cas9 strategy for gene editing across divergent rodent species: Targeting neural oxytocin receptors as a proof of concept by Boender, Arjen J, Boon, Marina, Albers, H Elliott, Eck, Samantha R, Fricker, Brandon A, Kelly, Aubrey M, LeDoux, Joseph E, Motta, Simone C, Shrestha, Prerana, Taylor, Jack H, Trainor, Brian C, Triana-Del Rio, Rodrigo, Young, Larry J

“…A major issue in neuroscience is the poor translatability of research results from preclinical studies in animals to clinical outcomes. Comparative…”
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Application of a Translational Profiling Approach for the Comparative Analysis of CNS Cell Types by Doyle, Joseph P., Dougherty, Joseph D., Heiman, Myriam, Schmidt, Eric F., Stevens, Tanya R., Ma, Guojun, Bupp, Sujata, Shrestha, Prerana, Shah, Rajiv D., Doughty, Martin L., Gong, Shiaoching, Greengard, Paul, Heintz, Nathaniel

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Application of BACarray for comparative analysis of CNS cell types by Doyle, Joseph P., Dougherty, Joseph D., Heiman, Myriam, Schmidt, Eric F., Stevens, Tanya R., Ma, Guojun, Bupp, Sujata, Shrestha, Prerana, Shah, Rajiv D., Doughty, Martin L., Gong, Shiaoching, Greengard, Paul, Heintz, Nathaniel

“…Comparative analysis of BACarray data can provide important insights into complex biological systems. As demonstrated in the accompanying paper, BACarray…”
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