Search Results - "Shrestha, Pradeep"

The Innate Immune System in Cardiovascular Diseases and Its Role in Doxorubicin-Induced Cardiotoxicity by Bhagat, Anchit, Shrestha, Pradeep, Kleinerman, Eugenie S

“…Innate immune cells are the early responders to infection and tissue damage. They play a critical role in the initiation and resolution of inflammation in…”
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In Search of the Perfect Photocage: Structure–Reactivity Relationships in meso-Methyl BODIPY Photoremovable Protecting Groups by Slanina, Tomáš, Shrestha, Pradeep, Palao, Eduardo, Kand, Dnyaneshwar, Peterson, Julie A, Dutton, Andrew S, Rubinstein, Naama, Weinstain, Roy, Winter, Arthur H, Klán, Petr

“…A detailed investigation of the photophysical parameters and photochemical reactivity of meso-methyl BODIPY photoremovable protecting groups was accomplished…”
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Solute accumulation differs in the vacuoles and apoplast of ripening grape berries by Keller, Markus, Shrestha, Pradeep M

“…Phloem unloading is thought to switch from a symplastic route to an apoplastic route at the beginning of ripening in grape berries and some other fleshy…”
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Efficient Far-Red/Near-IR Absorbing BODIPY Photocages by Blocking Unproductive Conical Intersections by Shrestha, Pradeep, Dissanayake, Komadhie C, Gehrmann, Elizabeth J, Wijesooriya, Chamari S, Mukhopadhyay, Atreyee, Smith, Emily A, Winter, Arthur H

“…Photocages are light-sensitive chemical protecting groups that give investigators control over activation of biomolecules using targeted light irradiation. A…”
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Sugar demand of ripening grape berries leads to recycling of surplus phloem water via the xylem by KELLER, MARKUS, ZHANG, YUN, SHRESTHA, PRADEEP M, BIONDI, MARCO, BONDADA, BHASKAR R

“…We tested the common assumption that fleshy fruits become dependent on phloem water supply because xylem inflow declines at the onset of ripening. Using two…”
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Structure–Activity Relationships of Antibody-Drug Conjugates: A Systematic Review of Chemistry on the Trastuzumab Scaffold by Matikonda, Siddharth S., McLaughlin, Ryan, Shrestha, Pradeep, Lipshultz, Carol, Schnermann, Martin J.

“…Antibody-drug conjugates (ADCs) are a rapidly growing class of cancer therapeutics that seek to overcome the low therapeutic index of conventional cytotoxic…”
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Molecular Epidemiology of Helicobacter pylori Infection in Nepal: Specific Ancestor Root by Miftahussurur, Muhammad, Sharma, Rabi Prakash, Shrestha, Pradeep Krishna, Suzuki, Rumiko, Uchida, Tomohisa, Yamaoka, Yoshio

“…Prevalence of Helicobacter pylori infection in Nepal, a low-risk country for gastric cancer, is debatable. To our knowledge, no studies have examined H. pylori…”
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Study of Oxygen Saturation by Pulse Oximetry and Arterial Blood Gas in ICU Patients: A Descriptive Cross-sectional Study by Rauniyar, Nabin, Pujari, Shyam, Shrestha, Pradeep

“…Introduction: Pulse oximetery is expected to be an indirect estimation of arterial oxygen saturation. However, there often are gaps between SpO2 and SaO2. This…”
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Doxorubicin-induced cardiotoxicity is mediated by neutrophils through release of neutrophil elastase by Bhagat, Anchit, Shrestha, Pradeep, Jeyabal, Prince, Peng, Zhanglong, Watowich, Stephanie S., Kleinerman, Eugenie S.

“…The mechanisms by which Doxorubicin (Dox) causes acute and late cardiotoxicity are not completely understood. One understudied area is the innate immune…”
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Consensus recommendations on sulfonylurea and sulfonylurea combinations in the management of Type 2 diabetes mellitus - International Task Force by Kalra, Sanjay, Bahendeka, Silver, Sahay, Rakesh, Ghosh, Sujoy, Md, Fariduddin, Orabi, Abbas, Ramaiya, Kaushik, Al Shammari, Sameer, Shrestha, Dina, Shaikh, Khalid, Abhayaratna, Sachitha, Shrestha, Pradeep, Mahalingam, Aravinthan, Askheta, Mazen, A. Rahim, Aly, Eliana, Fatimah, Shrestha, Hari, Chaudhary, Sandeep, Ngugi, Nancy, Mbanya, Jean, Aye, Than, Latt, Tint, Akanov, Zhanay, Syed, Abbas, Tandon, Nikhil, Unnikrishnan, A, Madhu, S, Jawa, Ali, Chowdhury, Subhankar, Bajaj, Sarita, Das, Ashok

“…For decades, sulfonylureas (SUs) have been important drugs in the antidiabetic therapeutic armamentarium. They have been used as monotherapy as well as…”
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Helicobacter pylori bab characterization in clinical isolates from Bhutan, Myanmar, Nepal and Bangladesh by Ansari, Shamshul, Kabamba, Evariste Tshibangu, Shrestha, Pradeep Krishna, Aftab, Hafeza, Myint, Thein, Tshering, Lotay, Sharma, Rabi Prakash, Ni, Nwe, Aye, Than Than, Subsomwong, Phawinee, Uchida, Tomohisa, Ratanachu-Ek, Thawee, Vilaichone, Ratha-Korn, Mahachai, Varocha, Matsumoto, Takashi, Akada, Junko, Yamaoka, Yoshio

“…Helicobacter pylori BabA is an important outer membrane protein that involves in the attachment to the gastric mucosa and enhances the virulence property of…”
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Catastrophic household expenditure on health in Nepal: a cross-sectional survey by Saito, Eiko, Gilmour, Stuart, Rahman, Md Mizanur, Gautam, Ghan Shyam, Shrestha, Pradeep Krishna, Shibuya, Kenji

“…To determine the incidence of - and illnesses commonly associated with - catastrophic household expenditure on health in Nepal. We did a cross-sectional…”
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Local immunomodulation Fas ligand-engineered biomaterials achieves allogeneic islet graft acceptance by Headen, Devon M, Woodward, Kyle B, Coronel, María M, Shrestha, Pradeep, Weaver, Jessica D, Zhao, Hong, Tan, Min, Hunckler, Michael D, Bowen, William S, Johnson, Christopher T, Shea, Lonnie, Yolcu, Esma S, García, Andrés J, Shirwan, Haval

“…Islet transplantation is a promising therapy for type 1 diabetes. However, chronic immunosuppression to control rejection of allogeneic islets induces…”
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Azathioprine‐induced pancytopenia: A case report by Sigdel, Keshav Raj, Thapa, Astha, Dahal, Agnimshwor, Panthi, Ramchandra, Adhikari, Krishan, Shrestha, Pradeep, Lama, Mipsang, Poudyal, Buddhi, Basnyat, Buddha

“…Azathioprine (AZA) is commonly used as immunosuppressive therapy for autoimmune diseases, including systemic lupus erythematosus (SLE). Myelosuppression is a…”
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Emerging Helicobacter pylori levofloxacin resistance and novel genetic mutation in Nepal by Miftahussurur, Muhammad, Shrestha, Pradeep Krishna, Subsomwong, Phawinee, Sharma, Rabi Prakash, Yamaoka, Yoshio

“…The prevalence of Helicobacter pylori antibiotic susceptibility in the Nepalese strains is untracked. We determined the antibiotic susceptibility for H. pylori…”
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Diagnostic Yield of Bronchoscopic Alveolar Lavage Gene Xpert MTB/Rif in Smear Negative Clinico-Radiologically Suspected Case of Pulmonary Tuberculosis by Bista, Bidesh, Karmacharya, Niraj, Hari Ghimire, Ram, Shrestha, Pradeep, Poudel, Deepak, Kurumbang, Janer, Mahato, Manoj, Raj Mishra, Deebya

“…Background: Early diagnosis of pulmonary tuberculosis is difficult but dreaded complications like cavitations, abscess, disseminations and fibrosis of lung…”
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Su1925 Molecular Epidemiology of Helicobacter pylori Infection in Nepal; The Mountainous Peoples Could Be a High-Risk Population by Miftahussurur, Muhammad, Sharma, Rabi P, Shrestha, Pradeep K, Suzuki, Rumiko, Shiota, Seiji, Uchida, Tomohisa, Yamaoka, Yoshio

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Inequality and inequity in healthcare utilization in urban Nepal: a cross-sectional observational study by Saito, Eiko, Gilmour, Stuart, Yoneoka, Daisuke, Gautam, Ghan Shyam, Rahman, Md Mizanur, Shrestha, Pradeep Krishna, Shibuya, Kenji

“…Inequality in access to quality healthcare is a major health policy challenge in many low-and middle-income countries. This study aimed to identify the major…”
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Use of nucleoside analogs in patients with chronic hepatitis B in Nepal: A prospective cohort study in a single hospital by Masaki, Naohiko, Shrestha, Pradeep Krishna, Nishimura, So, Ito, Kiyoaki, Sugiyama, Masaya, Mizokami, Masashi

“…Aim There still remain many concerns about the present status of antiviral therapy for chronic hepatitis B in developing countries in Asia, where the…”
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MANIFESTATION OF OPTIMAL ROUTE ALIGNMENT SELECTION OF RURAL ROAD USING GIS AND LEAST COST PATH (LCP) MODEL WITH ENGINEERING AND ENVIRONMENTAL SUITABILITY PERSPECTIVE: A CASE STUDY IN NEPAL by Sunari Magar, Rakesh, Shrestha, Pradeep Kumar, Kayastha, Prabin

“…For the economic growth and sustainable development of any country, the road networks play a pivotal role. Hence, the selection of best route alignment for the…”
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