Search Results - "Shrestha, Ajaya R."

Guanidine bridged nucleic acid (GuNA): an effect of a cationic bridged nucleic acid on DNA binding affinity by Shrestha, Ajaya R, Kotobuki, Yutaro, Hari, Yoshiyuki, Obika, Satoshi

“…A novel 2',4'-BNA/LNA analog bridged by guanidine, termed as guanidine bridged nucleic acid (GuNA), was synthesized and incorporated into oligonucleotides…”
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Synthesis and properties of thymidines with six-membered amide bridge by Hari, Yoshiyuki, Osawa, Takashi, Kotobuki, Yutaro, Yahara, Aiko, Shrestha, Ajaya R., Obika, Satoshi

“…Artificial thymidine monomers possessing amide or N-methylamide bridges were designed, synthesized, and introduced into oligonucleotides. UV-melting…”
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Development of gapmer antisense oligonucleotide with deoxyribonucleic guanidine (DNG) modifications by Kojima, Naoshi, Shrestha, Ajaya R., Akisawa, Takuya, Piao, Haishun, Kizawa, Hideki, Ohmiya, Yoshihiro, Kurita, Ryoji

“…The properties of gapmer antisense oligonucleotide (ASO) flanked by deoxyribonucleic guanidine (DNG) were investigated for the potential application in…”
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Synthesis and Properties of a Bridged Nucleic Acid with a Perhydro-1,2-oxazin-3-one Ring by Shrestha, Ajaya R, Hari, Yoshiyuki, Yahara, Aiko, Osawa, Takashi, Obika, Satoshi

“…A novel derivative of 2′,4′-bridged nucleic acid, named hydroxamate-bridged nucleic acid (HxNA), containing a six-membered perhydro-1,2-oxazin-3-one ring, was…”
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Synthesis, biological active molecular design, and molecular docking study of novel deazaflavin–cholestane hybrid compounds by Shrestha, Ajaya R., Shindo, Takashi, Ashida, Noriyuki, Nagamatsu, Tomohisa

“…Novel deazaflavin–cholestane hybrid compounds, 3′,8′-disubstituted-5′-deazacholest-2,4-dieno[2,3- g]pteridine-2′,4′(3′ H,8′ H)-diones, have been synthesized by…”
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Antitumor studies. Part 5: Synthesis, antitumor activity, and molecular docking study of 5-(monosubstituted amino)-2-deoxo-2-phenyl-5-deazaflavins by Shrestha, Ajaya R., Ali, Hamed I., Ashida, Noriyuki, Nagamatsu, Tomohisa

“…Various novel 5-(monosubstituted amino)-2-deoxo-2-phenyl-5-deazaflavins derivatives have been synthesized by direct coupling of 5-deazaflavins and N-alkyl or…”
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