Search Results - "Shram, S I"

Changes in the Transcription Profile of the Hippocampus in Response to Administration of the Tuftsin Analog Selank by Kolomin, T. A., Agapova, T. Yu, Agniullin, Ya. V., Shram, S. I., Shadrina, M. I., Slominskii, P. A., Limborskaya, S. A., Myasoedov, N. F.

“…We describe here our studies of the effects of single doses and courses of the synthetic tuftsin analog Selank (a peptide with the sequence…”
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Protein poly(ADP-ribosyl)ation system: Changes in development and aging as well as due to restriction of cell proliferation by Shilovsky, G. A., Shram, S. I., Morgunova, G. V., Khokhlov, A. N.

“…It is well known that the number of dividing cells in an organism decreases with age. The average rate of cell division in tissues and organs of a mature…”
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Biological Diversity and Remodeling of Cardiolipin in Oxidative Stress and Age-Related Pathologies by Shilovsky, G. A., Putyatina, T. S., Ashapkin, V. V., Yamskova, O. V., Lyubetsky, V. A., Sorokina, E. V., Shram, S. I., Markov, A. V., Vyssokikh, M. Y.

“…Age-related dysfunctions are accompanied by impairments in the mitochondrial morphology, activity of signaling pathway, and protein interactions. Cardiolipin…”
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7-Methylguanine Inhibits Colon Cancer Growth in Vivo by Kirsanov, K I, Fetisov, T I, Antoshina, E E, Gor'kova, T G, Trukhanova, L S, Shram, S I, Nagaev, I Yu, Zolotarev, Yu A, Qoura, L Abo, Pokrovsky, V S, Yakubovskaya, M G, Švedas, V K, Nilov, D K

“…7-Methylguanine (7-MG) is a natural inhibitor of poly(ADP-ribose) polymerase 1 and tRNA-guanine transglycosylase, the enzymatic activity of which is central…”
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Estimation of time-dependent microRNA expression patterns in brain tissue, leukocytes, and blood plasma of rats under photochemically induced focal cerebral ischemia by Gusar, V. A., Timofeeva, A. V., Zhanin, I. S., Shram, S. I., Pinelis, V. G.

“…miRNA expression over different time periods (24 and 48 h) using the quantitative RT-PCR and deep sequencing has been evaluated in a model of photochemically…”
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Formation of Spatial Memory in Rats with Ischemic Lesions to the Prefrontal Cortex; Effects of a Synthetic Analog of ACTH(4-7) by Silachev, D. N., Shram, S. I., Shakova, F. M., Romanova, G. A., Myasoedov, N. F.

“…Photochemically induced thrombosis of blood vessels in the prefrontal cortex in rats was shown to lead to ischemic infarcts in the lesion zone. Bilateral…”
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The protein poly(ADP-ribosyl)ation system: Its role in genome stability and lifespan determination by Shilovsky, G. A., Khokhlov, A. N., Shram, S. I.

“…The processes that lead to violation of genome integrity are known to increase with age. This phenomenon is caused both by increased production of reactive…”
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Pharmacokinetics of HLDF-6-AA Peptide in the Organism of Experimental Animals by Zolotarev, Yu. A., Dadayan, A. K., Kozik, V. S., Shram, S. I., Azev, V. N., Bogachouk, A. P., Lipkin, V. M., Myasoedov, N. F.

“…Pharmacokinetics of the promising antitumor peptide HLDF-6-AA (Ac-ThrGlyGluAsnHisArg-NH 2 ) was studied using its uniformly tritiated derivative. Experiments…”
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Proteolytic Hydrolysis of the Antitumor Peptide HLDF-6-AA in Blood Plasma by Zolotarev, Yu. A., Dadayan, A. K., Kozik, V. S., Shram, S. I., Nagaev, I. Yu, Azev, V. N., Bogachouk, A. P., Lipkin, V. M., Myasoedov, N. F.

“…HLDF-6 hexapeptide, which corresponds to the 41 TGENHR 46 fragment of human leukemia differentiation factor (HLDF), shows a wide range of neuroprotective,…”
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Doxorubicin causes transient activation of protein poly(ADP-ribosyl)ation in H9c2 cardiomyocytes by Efremova, A. S., Shram, S. I., Myasoedov, N. F.

“…Possible involvement of the system of protein poly(ADP-ribosyl)ation in the mechanisms of cardiotoxicity of doxorubicin, one of the most frequently used…”
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Poly(ADP-ribose)-polymerase-1 and aging: experimental study of possible relationship on stationary cell cultures by Shram, S I, Shilovskii, G A, Khokhlov, A N

“…Experiments on "stationary aging" cultures of B11dii-FAF28 Chinese hamster cells showed that contact inhibition of cell growth and further culturing of cells…”
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Neuroprotective and antiamnesic effects of Semax during experimental ischemic infarction of the cerebral cortex by Romanova, G A, Silachev, D N, Shakova, F M, Kvashennikova, Yu N, Viktorov, I V, Shram, S I, Myasoedov, N F

“…Semax had a pronounced neuroprotective and antiamnesic effect during focal photoinduced ischemia of the prefrontal cortex. Intranasal administration of Semax…”
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The penetration of 5-oxo-Pro-Arg-Pro into the brain and the major metabolic pathways of this peptide in the rat brain and blood at the intranasal and intravenous administration by Shevchenko, K. V., Nagaev, I. Yu, Shevchenko, V. P., Andreeva, L. A., Shram, S. I., Myasoedov, N. F.

“…It was shown that the neuroactive peptide 5-oxo-Pro-Arg-Pro (5-oxo-PRP) is detected in the brain in the time interval of 5–120 min after it was intravenously…”
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The role of angiostatins in diabetic complications by Tykhomyrov, A. A., Shram, S. I., Grinenko, T. V.

“…Angiogenesis, a process of formation of new blood vessels form pre-existing vessels, is regulated by a large number of peptide factors. Imbalance of pro- and…”
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Expression changes caused by the peptide semax in the intracellular signal pathway genes in rat hippocamp by Agapova, T Yu, Agniullin, Ya V, Silachev, D N, Shadrina, M I, Slominsky, P A, Shram, S I, Limborskaya, S A, Myasoedov, N F

“…(ProQuest: Abstract omitted; see image)[PUBLICATION ABSTRACT]…”
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The Qualitative Analysis of the Amide Derivative of HLDF-6 Peptide and Its Metabolites with the Use of Tritium- and Deuterium-Labeled Derivatives by Zolotarev, A, Dadayan, A K, Kost, N V, Voevodina, M E, Sokolov, O Y, Kozik, V S, Shram, S I, Azev, V N, Bocharov, E V, Bogachouk, A P, Lipkin, V M, Myasoedov, N F

“…The goal of the study was to elaborate the pharmacokinetics methods of the amide derivative of peptide HLDF-6 (TGENHR-NH2) and its range of nootropic and…”
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The selective toxic effect of dialdehyde derivatives of pyrimidine nucleosides on human ovarian cancer cells by Efremova, A. S., Shram, S. I., Drenichev, M. S., Posypanova, G. A., Myasoedov, N. F., Mikhailov, S. N.

“…The effect of synthetic nucleoside derivatives on the growth and survival of cultured human ovarian cancer cells (line SKOV-3) and normal human lung…”
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Effect of Semax peptide on survival of cultured rat pheochromocytoma cells during oxidative stress by Safarova, E R, Shram, S I, Zolotarev, Yu A, Myasoedov, N F

“…We studied the effects of Semax (antiinsulin peptide with neuroprotective effect) on the survival of cultured rat pheochromocytoma cell after oxidative stress…”
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Synthesis of a new fluorescent analogue of proglyprol and study of the mechanisms of its transport into the cultured rat pheochromocytoma cells by Akimov, M. G., Gretskaya, N. M., Sinitsyna, I. A., Efremova, A. S., Andreeva, L. A., Shram, S. I., Bezuglov, V. V., Myasoedov, N. F.

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Transcriptome alteration in hippocampus under the treatment of tuftsin analog Selank by Kolomin, T A, Agapova, T Iu, Agniullin, Ia V, Shram, S I, Shadrina, M I, Slominskiĭ, P A, Limborskaia, S A, Miasoedov, I F

“…The effect of single and course administration of Selank (Thr-Lys-Pro-Arg-Pro-Gly-Pro) in the dose 200 microg/kg on the rat hippocampus transcriptional profile…”
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