Search Results - "Showell, Jordan"
-
1
Characteristics of anti-CD19 CAR T cell infusion products associated with efficacy and toxicity in patients with large B cell lymphomas
Published in Nature medicine (01-12-2020)“…Autologous chimeric antigen receptor (CAR) T cell therapies targeting CD19 have high efficacy in large B cell lymphomas (LBCLs), but long-term remissions are…”
Get full text
Journal Article -
2
SPEG (Striated Muscle Preferentially Expressed Protein Kinase) Is Essential for Cardiac Function by Regulating Junctional Membrane Complex Activity
Published in Circulation research (06-01-2017)“…RATIONALE:Junctional membrane complexes (JMCs) in myocytes are critical microdomains, in which excitation–contraction coupling occurs. Structural and…”
Get full text
Journal Article -
3
Subtype-specific and co-occurring genetic alterations in B-cell non-Hodgkin lymphoma
Published in Haematologica (Roma) (01-03-2022)“…B-cell non-Hodgkin lymphoma (B-NHL) encompasses multiple clinically and phenotypically distinct subtypes of malignancy with unique molecular etiologies. Common…”
Get full text
Journal Article -
4
Novel Junctophilin-2 Mutation A405S Is Associated With Basal Septal Hypertrophy and Diastolic Dysfunction
Published in JACC. Basic to translational science (01-02-2017)“…Visual Abstract…”
Get full text
Journal Article -
5
DTX1 Controls Germinal Center B-Cell Development and Lymphomagenesis
Published in Blood (15-11-2022)Get full text
Journal Article -
6
Junctophilin-2 gene therapy rescues heart failure by normalizing RyR2-mediated Ca2+ release
Published in International journal of cardiology (15-12-2016)“…Junctophilin-2 (JPH2) is the primary structural protein for the coupling of transverse (T)-tubule associated cardiac L-type Ca channels and type-2 ryanodine…”
Get full text
Journal Article -
7
Abstract A36: Building of a large B-cell lymphoma (LBCL) patient-derived xenograft (PDX) repository
Published in Blood cancer discovery (06-09-2022)“…Abstract Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous B-cell malignancy that consists of no fewer than 5 genetic subtypes. Cell lines have been a…”
Get full text
Journal Article -
8
-
9
Abstract 35: Pseudo-knockin Mice Expressing JPH2-A399S Develop Cardiac Hypertrophy by Magnetic Resonance Imaging
Published in Circulation research (17-07-2015)“…Abstract only Background: Dysfunctional intracellular Ca2+ handling has been implicated in adverse cardiac remodeling leading to hypertrophy and failure…”
Get full text
Journal Article -
10
Junctophilin-2 gene therapy rescues heart failure by normalizing RyR2-mediated Ca 2 + release
Published in International journal of cardiology (15-12-2016)“…Abstract Background Junctophilin-2 (JPH2) is the primary structural protein for coupling of transverse (T)-tubule associated cardiac L-type Ca channels and…”
Get full text
Journal Article