Search Results - "Showalter, R."

Identification of small molecules using accurate mass MS/MS search by Kind, Tobias, Tsugawa, Hiroshi, Cajka, Tomas, Ma, Yan, Lai, Zijuan, Mehta, Sajjan S., Wohlgemuth, Gert, Barupal, Dinesh Kumar, Showalter, Megan R., Arita, Masanori, Fiehn, Oliver

“…Tandem mass spectral library search (MS/MS) is the fastest way to correctly annotate MS/MS spectra from screening small molecules in fields such as…”
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A metabolome atlas of the aging mouse brain by Ding, Jun, Ji, Jian, Rabow, Zachary, Shen, Tong, Folz, Jacob, Brydges, Christopher R., Fan, Sili, Lu, Xinchen, Mehta, Sajjan, Showalter, Megan R., Zhang, Ying, Araiza, Renee, Bower, Lynette R., Lloyd, K. C. Kent, Fiehn, Oliver

“…The mammalian brain relies on neurochemistry to fulfill its functions. Yet, the complexity of the brain metabolome and its changes during diseases or aging…”
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Epimetabolites: discovering metabolism beyond building and burning by Showalter, Megan R, Cajka, Tomas, Fiehn, Oliver

“…[Display omitted] •Epimetabolites are modified classic metabolites with new roles.•Example roles include regulation of tumorigenesis, inflammation and…”
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Structure Annotation of All Mass Spectra in Untargeted Metabolomics by Blaženović, Ivana, Kind, Tobias, Sa, Michael R, Ji, Jian, Vaniya, Arpana, Wancewicz, Benjamin, Roberts, Bryan S, Torbašinović, Hrvoje, Lee, Tack, Mehta, Sajjan S, Showalter, Megan R, Song, Hosook, Kwok, Jessica, Jahn, Dieter, Kim, Jayoung, Fiehn, Oliver

“…Urine metabolites are used in many clinical and biomedical studies but usually only for a few classic compounds. Metabolomics detects vastly more metabolic…”
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The solar nebula origin of (486958) Arrokoth, a primordial contact binary in the Kuiper Belt by McKinnon, W B, Richardson, D C, Marohnic, J C, Keane, J T, Grundy, W M, Hamilton, D P, Nesvorný, D, Umurhan, O M, Lauer, T R, Singer, K N, Stern, S A, Weaver, H A, Spencer, J R, Buie, M W, Moore, J M, Kavelaars, J J, Lisse, C M, Mao, X, Parker, A H, Porter, S B, Showalter, M R, Olkin, C B, Cruikshank, D P, Elliott, H A, Gladstone, G R, Parker, J Wm, Verbiscer, A J, Young, L A

“…The New Horizons spacecraft's encounter with the cold classical Kuiper Belt object (486958) Arrokoth (provisional designation 2014 MU ) revealed a…”
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The Emerging and Diverse Roles of Bis(monoacylglycero) Phosphate Lipids in Cellular Physiology and Disease by Showalter, Megan R, Berg, Anastasia L, Nagourney, Alexander, Heil, Hailey, Carraway, 3rd, Kermit L, Fiehn, Oliver

“…Although understudied relative to many phospholipids, accumulating evidence suggests that bis(monoacylglycero)phosphate (BMP) is an important class of…”
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Inborn Errors of Metabolism in the Era of Untargeted Metabolomics and Lipidomics by Ismail, Israa T, Showalter, Megan R, Fiehn, Oliver

“…Inborn errors of metabolism (IEMs) are a group of inherited diseases with variable incidences. IEMs are caused by disrupting enzyme activities in specific…”
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New Horizons Observations of the Cosmic Optical Background by Lauer, Tod R., Postman, Marc, Weaver, Harold A., Spencer, John R., Stern, S. Alan, Buie, Marc W., Durda, Daniel D., Lisse, Carey M., Poppe, A. R., Binzel, Richard P., Britt, Daniel T., Buratti, Bonnie J., Cheng, Andrew F., Grundy, W. M., Horányi, Mihaly, Kavelaars, J. J., Linscott, Ivan R., McKinnon, William B., Moore, Jeffrey M., Núñez, J. I., Olkin, Catherine B., Parker, Joel W., Porter, Simon B., Reuter, Dennis C., Robbins, Stuart J., Schenk, Paul, Showalter, Mark R., Singer, Kelsi N., Verbiscer, Anne J., Young, Leslie A.

“…Abstract We used existing data from the New Horizons Long-range Reconnaissance Imager (LORRI) to measure the optical-band (0.4 ≲  λ  ≲ 0.9 μ m) sky brightness…”
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Hubble Detects the Start of a New Saturn Ring Spoke Season by Simon, Amy A., Nicholson, Philip D., Tiscareno, Matthew S., Showalter, Mark R., McDonald, Troy

“…Saturn’s ring spokes typically appear over an 8-year duration centered on equinox. Hubble Space Telescope observations in 2021 indicate the beginning of a new…”
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TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes by Miklas, Jason W., Clark, Elisa, Levy, Shiri, Detraux, Damien, Leonard, Andrea, Beussman, Kevin, Showalter, Megan R., Smith, Alec T., Hofsteen, Peter, Yang, Xiulan, Macadangdang, Jesse, Manninen, Tuula, Raftery, Daniel, Madan, Anup, Suomalainen, Anu, Kim, Deok-Ho, Murry, Charles E., Fiehn, Oliver, Sniadecki, Nathan J., Wang, Yuliang, Ruohola-Baker, Hannele

“…Mitochondrial trifunctional protein deficiency, due to mutations in hydratase subunit A (HADHA), results in sudden infant death syndrome with no cure. To…”
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Metabolomic characteristics of cholesterol-induced non-obese nonalcoholic fatty liver disease in mice by Tu, Lan N., Showalter, Megan R., Cajka, Tomas, Fan, Sili, Pillai, Viju V., Fiehn, Oliver, Selvaraj, Vimal

“…Nonalcoholic fatty liver disease (NAFLD) in non-obese patients remains a clinical condition with unclear etiology and pathogenesis. Using a metabolomics…”
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Constraining the symmetry energy with heavy-ion collisions and Bayesian analyses by Morfouace, P., Tsang, C.Y., Zhang, Y., Lynch, W.G., Tsang, M.B., Coupland, D.D.S., Youngs, M., Chajecki, Z., Famiano, M.A., Ghosh, T.K., Jhang, G., Lee, Jenny, Liu, H., Sanetullaev, A., Showalter, R., Winkelbauer, J.

“…Efficiency corrected single ratios of neutron and proton spectra in central Sn112+112Sn and Sn124+124Sn collisions at 120 MeV/u are combined with double ratios…”
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Obesogenic diets alter metabolism in mice by Showalter, Megan R, Nonnecke, Eric B, Linderholm, A L, Cajka, Tomas, Sa, Michael R, Lönnerdal, Bo, Kenyon, Nicholas J, Fiehn, Oliver

“…Obesity and accompanying metabolic disease is negatively correlated with lung health yet the exact mechanisms by which obesity affects the lung are not well…”
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The orbits and masses of satellites of Pluto by Brozović, Marina, Showalter, Mark R., Jacobson, Robert A., Buie, Marc W.

“…•We report on pre-discovery of Kerberos from 2006 HST images.•We report on new 2010–2012 HST astrometry for Nix, Hydra, Kerberos, and Styx.•The astrometry of…”
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The seventh inner moon of Neptune by Showalter, M. R., de Pater, I., Lissauer, J. J., French, R. S.

“…During its 1989 flyby, the Voyager 2 spacecraft imaged six small moons of Neptune, all with orbits well interior to that of the large, retrograde moon Triton 1…”
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The narrow fracture approximation by channeled flow by Morales, Fernando, Showalter, R.E.

“…The singular problem of non-stationary Darcy flow in a region containing a narrow channel of width O ( ϵ ) and high permeability O ( 1 ϵ ) is shown to be well…”
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Diffusion in Poro-Elastic Media by Showalter, R.E.

“…Existence, uniqueness, and regularity theory is developed for a general initial-boundary-value problem for a system of partial differential equations which…”
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Close-range remote sensing of Saturn's rings during Cassini's ring-grazing orbits and Grand Finale by Tiscareno, Matthew S, Nicholson, Philip D, Cuzzi, Jeffrey N, Spilker, Linda J, Murray, Carl D, Hedman, Matthew M, Colwell, Joshua E, Burns, Joseph A, Brooks, Shawn M, Clark, Roger N, Cooper, Nicholas J, Deau, Estelle, Ferrari, Cecile, Filacchione, Gianrico, Jerousek, Richard G, Le Mouélic, Stéphane, Morishima, Ryuji, Pilorz, Stu, Rodriguez, Sébastien, Showalter, Mark R, Badman, Sarah V, Baker, Emily J, Buratti, Bonnie J, Baines, Kevin H, Sotin, Christophe

“…Saturn's rings are an accessible exemplar of an astrophysical disk, tracing the Saturn system's dynamical processes and history. We present close-range…”
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Observation of Long-Range Three-Body Coulomb Effects in the Decay of Ne 16 by Brown, K. W., Charity, R. J., Sobotka, L. G., Chajecki, Z., Grigorenko, L. V., Egorova, I. A., Parfenova, Yu. L., Zhukov, M. V., Bedoor, S., Buhro, W. W., Elson, J. M., Lynch, W. G., Manfredi, J., McNeel, D. G., Reviol, W., Shane, R., Showalter, R. H., Tsang, M. B., Winkelbauer, J. R., Wuosmaa, A. H.

“…The interaction of an E/A = 57.6-MeV Ne-17 beam with a Be target is used to populate levels in Ne-16 following neutron knockout reactions. The decay of 16Ne…”
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Improving Outcomes for Women With Metastatic HER2-Positive and HER2-Low Breast Cancer by L. Graff, MD, FACP, FASCO, Stephanie, McGinn, MSN, APRN, ACNP-BC, Christine, R. Showalter, MSN, APRN, FNP-BC, AOCNP, Jeanine

“…At JADPRO Live 2023, presenters discussed recent updates to clinical practice in metastatic HER2-positive metastatic breast cancer. During the session, they…”
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