Search Results - "Shoura, Massa J."
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Recompleting the Caenorhabditis elegans genome
Published in Genome research (01-06-2019)“…was the first multicellular eukaryotic genome sequenced to apparent completion. Although this assembly employed a standard strain (N2), it used sequence data…”
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Journal Article -
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Intricate and Cell Type-Specific Populations of Endogenous Circular DNA (eccDNA) in Caenorhabditis elegans and Homo sapiens
Published in G3 : genes - genomes - genetics (01-10-2017)“…Investigations aimed at defining the 3D configuration of eukaryotic chromosomes have consistently encountered an endogenous population of chromosome-derived…”
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An Extensive Meta-Metagenomic Search Identifies SARS-CoV-2-Homologous Sequences in Pangolin Lung Viromes
Published in mSphere (06-05-2020)“…In numerous instances, tracking the biological significance of a nucleic acid sequence can be augmented through the identification of environmental niches in…”
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The thermodynamics of DNA loop formation, from J to Z
Published in Biochemical Society transactions (01-04-2013)“…The formation of DNA loops is a ubiquitous theme in biological processes, including DNA replication, recombination and repair, and gene regulation. These loops…”
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Contribution of Fluorophore Dynamics and Solvation to Resonant Energy Transfer in Protein-DNA Complexes: A Molecular-Dynamics Study
Published in Biophysical journal (05-08-2014)“…In Förster resonance energy transfer (FRET) experiments, extracting accurate structural information about macromolecules depends on knowing the positions and…”
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Immune imprinting, breadth of variant recognition, and germinal center response in human SARS-CoV-2 infection and vaccination
Published in Cell (17-03-2022)“…During the SARS-CoV-2 pandemic, novel and traditional vaccine strategies have been deployed globally. We investigated whether antibodies stimulated by mRNA…”
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7
Deconvolution of nucleic-acid length distributions: a gel electrophoresis analysis tool and applications
Published in Nucleic acids research (19-09-2019)“…Next-generation DNA-sequencing (NGS) technologies, which are designed to streamline the acquisition of massive amounts of sequencing data, are nonetheless…”
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Loop-closure kinetics reveal a stable, right-handed DNA intermediate in Cre recombination
Published in Nucleic acids research (07-05-2020)“…In Cre site-specific recombination, the synaptic intermediate is a recombinase homotetramer containing a pair of loxP DNA target sites. The enzyme system's…”
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Measurements of DNA-loop formation via Cre-mediated recombination
Published in Nucleic acids research (01-08-2012)“…The Cre-recombination system has become an important tool for genetic manipulation of higher organisms and a model for site-specific DNA-recombination…”
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10
Quantitative Characterization of Gel Electrophoresis Images
Published in Biophysical journal (02-02-2018)Get full text
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11
Circulomics: The Structural Genomics of Endogenous and Exogenous Extrachromosomal Circular DNAs
Published in Biophysical journal (02-02-2018)Get full text
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Investigating Cre-Recombinase-Mediated DNA Looping using FRET
Published in Biophysical journal (28-01-2014)Get full text
Journal Article -
13
Deconvoluting complex correlates of COVID-19 severity with a multi-omic pandemic tracking strategy
Published in Nature communications (30-08-2022)“…The SARS-CoV-2 pandemic has differentially impacted populations across race and ethnicity. A multi-omic approach represents a powerful tool to examine risk…”
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Journal Article -
14
Structural probing of the longest-lived intermediate in the Cre-recombination pathway
Published 01-01-2014“…Advances in our quantitative understanding of thermodynamically driven protein-mediated DNA-looping depend on a detailed consideration of the mechanics of loop…”
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Dissertation -
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Investigations of Cre-recombinase-mediated DNA-loop formation using Förster resonance energy transfer (FRET)
Published 01-01-2013“…The interior of a cell is a crowded and fluctuating environment where DNA and other biomolecules are both highly constrained and subject to many mechanical…”
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Dissertation -
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Investigations of Cre-recombinase-mediated DNA-loop formation using Forster resonance energy transfer (FRET)
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Dissertation