Search Results - "Shou, I"

Predicting the emission wavelength of organic molecules using a combinatorial QSAR and machine learning approach by Ye, Zong-Rong, Huang, I.-Shou, Chan, Yu-Te, Li, Zhong-Ji, Liao, Chen-Cheng, Tsai, Hao-Rong, Hsieh, Meng-Chi, Chang, Chun-Chih, Tsai, Ming-Kang

“…Organic fluorescent molecules play critical roles in fluorescence inspection, biological probes, and labeling indicators. More than ten thousand organic…”
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Downregulated miR329 and miR410 promote the proliferation and invasion of oral squamous cell carcinoma by targeting Wnt-7b by Shiah, Shine-Gwo, Hsiao, Jenn-Ren, Chang, Wei-Min, Chen, Ya-Wen, Jin, Ying-Tai, Wong, Tung-Yiu, Huang, Jehn-Shyun, Tsai, Sen-Tien, Hsu, Yuan-Ming, Chou, Sung-Tau, Yen, Yi-Chen, Jiang, Shih Sheng, Shieh, Yi-Shing, Chang, I-Shou, Hsiao, Michael, Chang, Jang-Yang

“…microRNA (miRNA) dysregulation contributes widely to human cancer but has not been fully assessed in oral cancers. In this study, we conducted a global…”
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Association between fetal exposure to phthalate endocrine disruptor and genome-wide DNA methylation at birth by Chen, Chung-Hsing, Jiang, Shih Sheng, Chang, I-Shou, Wen, Hui-Ju, Sun, Chien-Wen, Wang, Shu-Li

“…Phthalic acid esters are ubiquitous and antiandrogenic, and may cause systemic effects in humans, particularly with in utero exposure. Epigenetic modification,…”
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Cdc7-Dbf4-mediated phosphorylation of HSP90-S164 stabilizes HSP90-HCLK2-MRN complex to enhance ATR/ATM signaling that overcomes replication stress in cancer by Cheng, An Ning, Fan, Chi-Chen, Lo, Yu-Kang, Kuo, Cheng-Liang, Wang, Hui-Chun, Lien, I.-Hsin, Lin, Shu-Yu, Chen, Chung-Hsing, Jiang, Shih Sheng, Chang, I.-Shou, Juan, Hsueh-Fen, Lyu, Ping-Chiang, Lee, Alan Yueh-Luen

“…Cdc7-Dbf4 kinase plays a key role in the initiation of DNA replication and contributes to the replication stress in cancer. The activity of human Cdc7-Dbf4…”
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Epigenetic Switch between SOX2 and SOX9 Regulates Cancer Cell Plasticity by Lin, Sheng-Chieh, Chou, Yu-Ting, Jiang, Shih Sheng, Chang, Junn-Liang, Chung, Chih-Hung, Kao, Yu-Rung, Chang, I-Shou, Wu, Cheng-Wen

“…Cell differentiation within stem cell lineages can check proliferative potential, but nodal pathways that can limit tumor growth are obscure. Here, we report…”
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Interplay between Polarizability and Hydrogen Bond Network of Water: Reparametrizing the Flexible Single-Point-Charge Water Model by the Nonlinear Adaptive Force Matching Approach by Huang, I-Shou, Tsai, Ming-Kang

“…An adaptive force matching (AFM) scheme using the nonlinear optimization to reparametrize the three-site, flexible, and polarizable single-point-charge (SPC)…”
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Mitochondrial Lon sequesters and stabilizes p53 in the matrix to restrain apoptosis under oxidative stress via its chaperone activity by Sung, Ya-Ju, Kao, Ting-Yu, Kuo, Cheng-Liang, Fan, Chi-Chen, Cheng, An Ning, Fang, Wei-Cheng, Chou, Han-Yu, Lo, Yu-Kang, Chen, Chung-Hsing, Jiang, Shih Sheng, Chang, I-Shou, Hsu, Chun-Hua, Lee, Jin-Ching, Lee, Alan Yueh-Luen

“…Mitochondrial Lon is a multi-function matrix protease with chaperone activity. However, little literature has been undertaken into detailed investigations on…”
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Dose-response technique combined with stable isotope tracing for drug metabolite profiling by using high-resolution mass spectrometry by Lin, I-Shou, Chuang, Chia-Ying Anderin, Shih, Chia-Lung

“…Mass spectrometry metabolomics-based data-processing approaches have been developed for drug metabolite profiling. However, existing approaches cannot be used…”
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The Association Between Dementia and Long-Term Use of Benzodiazepine in the Elderly: Nested Case–Control Study Using Claims Data by Wu, Chi-Shin, M.D., M.Sc, Wang, Sheng-Chang, M.D., M.Sc, Chang, I-Shou, Ph.D, Lin, Keh-Ming, M.D., M.P.H

“…Objectives: The aim of this study was to examine the association between long-term benzodiazepines (BZDs) use and the risk of dementia. Design:…”
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Multi-omics analysis identifies CpGs near G6PC2 mediating the effects of genetic variants on fasting glucose by Chung, Ren-Hua, Chiu, Yen-Feng, Wang, Wen-Chang, Hwu, Chii-Min, Hung, Yi-Jen, Lee, I-Te, Chuang, Lee-Ming, Quertermous, Thomas, Rotter, Jerome I., Chen, Yii-Der I., Chang, I-Shou, Hsiung, Chao A.

“…Aims/hypothesis An elevated fasting glucose level in non-diabetic individuals is a key predictor of type 2 diabetes. Genome-wide association studies (GWAS)…”
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Prevalence of comorbidities and their impact on survival among older adults with the five most common cancers in Taiwan: a population study by Chien, Li-Hsin, Tseng, Tzu-Jui, Chen, Tzu-Yu, Chen, Chung-Hsing, Chen, Chia-Yu, Jiang, Hsin-Fang, Tsai, Fang-Yu, Ku, Hsiu-Ying, Jiang, Shih Sheng, Hsiung, Chao A., Liu, Tsang-Wu, Chang, I-Shou

“…Because of the cancer incidence increase and population aging in Taiwan, we aimed to assess the cancer prevalence, to summarize the comorbidities of older…”
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Solvation Dynamics of CO₂(g) by Monoethanolamine at the Gas-Liquid Interface: A Molecular Mechanics Approach by Huang, I-Shou, Li, Jia-Jen, Tsai, Ming-Kang

“…A classical force field approach was used to characterize the solvation dynamics of high-density CO₂(g) by monoethanolamine (MEA) at the air-liquid interface…”
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Harnessing hepatitis B core-related antigen measurement to optimize posttreatment monitoring by Tsai, Ying-Nan, Wu, Jia-Ling, Hsu, Yao-Chun

“…[...]modeling a time-varying explanatory variable is distinctly different from analyzing changes between repeated measurements over time, as time-varying…”
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Epidemiologic Features of Kawasaki Disease in Taiwan, 2003-2006 by Huang, Wen-Chan, Huang, Li-Min, Chang, I-Shou, Chang, Luan-Yin, Chiang, Bor-Luen, Chen, Pei-Jer, Wu, Mei-Hwan, Lue, Hung-Chi, Lee, Chun-Yun, and Kawasaki Disease Research Group

“…Kawasaki disease is the leading cause of acquired heart disease in children worldwide. This study characterizes the epidemiology of Kawasaki disease in Taiwan…”
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Wild-type p53 upregulates an early onset breast cancer-associated gene GAS7 to suppress metastasis via GAS7–CYFIP1-mediated signaling pathway by Chang, Jer-Wei, Kuo, Wen-Hung, Lin, Chiao-Mei, Chen, Wen-Ling, Chan, Shih-Hsuan, Chiu, Meng-Fan, Chang, I-Shou, Jiang, Shih-Sheng, Tsai, Fang-Yu, Chen, Chung-Hsing, Huang, Pei-Hsin, Chang, King-Jen, Lin, Kai-Ti, Lin, Sheng-Chieh, Wang, Ming-Yang, Uen, Yih-Huei, Tu, Chi-Wen, Hou, Ming-Feng, Tsai, Shih-Feng, Shen, Chen-Yang, Tung, Shiao-Lin, Wang, Lu-Hai

“…The early onset breast cancer patients (age ≤ 40) often display higher incidence of axillary lymph node metastasis, and poorer five-year survival than the…”
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Prevalence and genetic characterization of hepatitis E virus in domestic Bactrian camels in northern China: Identification of a novel HEV8 subtype by LU, Gang, YIN, Xin, LIU, Yan-qin, XIE, Jin-xin, LI, Shou-jun

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Cardiometabolic disorder reduces survival prospects more than suboptimal body mass index irrespective of age or gender: a longitudinal study of 377,929 adults in Taiwan by Hsu, Chih-Cheng, Wahlqvist, Mark L, Wu, I-Chien, Chang, Yu-Hung, Chang, I-Shou, Tsai, Yi-Fen, Liu, Ting-Ting, Tsao, Chwen Keng, Hsiung, Chao A

“…The effect of cardio-metabolic profile on the relationship of body mass index (BMI) with mortality is unclear. The aim of this study was to explore association…”
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Upregulation of CISD2 augments ROS homeostasis and contributes to tumorigenesis and poor prognosis of lung adenocarcinoma by Li, Shih-Miao, Chen, Chung-Hsing, Chen, Ya-Wen, Yen, Yi-Chen, Fang, Wen-Tsen, Tsai, Fang-Yu, Chang, Junn-Liang, Shen, Ying-Ying, Huang, Shiu-Feng, Chuu, Chih-Pin, Chang, I-Shou, Hsiung, Chao A., Jiang, Shih Sheng

“…CISD2 is a redox-sensitive gene critical for normal development and mitochondrial integrity. CISD2 was known to have aberrant expression in several types of…”
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Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia by Lan, Qing, Hsiung, Chao A, Matsuo, Keitaro, Seow, Adeline, Wang, Zhaoming, Hosgood, H Dean, Chen, Kexin, Wang, Jiu-Cun, Chatterjee, Nilanjan, Hu, Wei, Wong, Maria Pik, Zheng, Wei, Caporaso, Neil, Park, Jae Yong, Kim, Yeul Hong, Kim, Young Tae, Burdett, Laurie, Yuenger, Jeffrey, Chang, I-Shou, Mitsudomi, Tetsuya, Chang, Gee-Chen, Bassig, Bryan A, Wei, Fusheng, Wu, Chen, An, She-Juan, Qian, Biyun, Lee, Victor Ho Fun, Lu, Daru, Liu, Jianjun, Jeon, Hyo-Sung, Sung, Jae Sook, Kim, Jin Hee, Tsai, Ying-Huang, Jung, Yoo Jin, Guo, Huan, Hu, Zhibin, Hutchinson, Amy, Klein, Robert, Chung, Charles C, Oh, In-Jae, Chen, Kuan-Yu, He, Xingzhou, Wu, Wei, Huang, Ming-Shyan, Zheng, Hong, Wang, Junwen, Zhao, Xueying, Li, Yuqing, Choi, Jin Eun, Park, Kyong Hwa, Shu, Xiao-Ou, Chen, Yuh-Min, Liu, Li, Kang, Chang Hyun, Hu, Lingmin, Chen, Chung-Hsing, Pao, William, Kim, Young-Chul, Yang, Tsung-Ying, Xu, Jun, Guan, Peng, Tan, Wen, Wang, Chih-Liang, Li, Haixin, Sihoe, Alan Dart Loon, Zhao, Zhenhong, Chen, Ying, Choi, Yi Young, Hung, Jen-Yu, Kim, Jun Suk, Cai, Qiuyin, Park, In Kyu, Xu, Ping, Dong, Jing, Kim, Christopher, He, Qincheng, Perng, Reury-Perng, Kohno, Takashi, Vermeulen, Roel, Wu, Junjie, Lim, Wei-Yen, Chen, Kun-Chieh, Chow, Wong-Ho, Ji, Bu-Tian, Chan, John K C, Li, Yao-Jen, Yokota, Jun, Li, Jihua, Chen, Hongyan, Xiang, Yong-Bing, Yu, Chong-Jen, Kunitoh, Hideo, Wu, Guoping, Lo, Yen-Li, Shiraishi, Kouya, Lin, Hsien-Chih, Wu, Yi-Long, Yang, Pan-Chyr, Zhou, Baosen, Shin, Min-Ho

“…Qing Lan and colleagues report the results of a genome-wide association study of lung cancer in never-smoking women from Asia. They identify three new…”
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Winner's Curse Correction and Variable Thresholding Improve Performance of Polygenic Risk Modeling Based on Genome-Wide Association Study Summary-Level Data by Shi, Jianxin, Park, Ju-Hyun, Duan, Jubao, Berndt, Sonja T, Moy, Winton, Yu, Kai, Song, Lei, Wheeler, William, Hua, Xing, Silverman, Debra, Garcia-Closas, Montserrat, Hsiung, Chao Agnes, Figueroa, Jonine D, Cortessis, Victoria K, Malats, Núria, Karagas, Margaret R, Vineis, Paolo, Chang, I-Shou, Lin, Dongxin, Zhou, Baosen, Seow, Adeline, Matsuo, Keitaro, Hong, Yun-Chul, Caporaso, Neil E, Wolpin, Brian, Jacobs, Eric, Petersen, Gloria M, Klein, Alison P, Li, Donghui, Risch, Harvey, Sanders, Alan R, Hsu, Li, Schoen, Robert E, Brenner, Hermann, Stolzenberg-Solomon, Rachael, Gejman, Pablo, Lan, Qing, Rothman, Nathaniel, Amundadottir, Laufey T, Landi, Maria Teresa, Levinson, Douglas F, Chanock, Stephen J, Chatterjee, Nilanjan

“…Recent heritability analyses have indicated that genome-wide association studies (GWAS) have the potential to improve genetic risk prediction for complex…”
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