Search Results - "Shon, Jong Cheol"
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Terfenadone is a strong inhibitor of CYP2J2 present in the human liver and intestinal microsomes
Published in Drug metabolism and pharmacokinetics (01-06-2018)“…Cytochrome P450 2J2 (CYP2J2) is involved in the metabolism of drugs, including albendazole, astemizole, ebastine, and endogenous substrates. In a previous…”
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2
Sphingolipids Modulate Secretion of Glycosylphosphatidylinositol-Anchored Plasmodesmata Proteins and Callose Deposition
Published in Plant physiology (Bethesda) (01-09-2020)“…Arabidopsis glucosyl sphingolipid-modulated plasmodesmal gating involves modulation of the glycosylphosphatidylinositol-anchored PdBG2 protein secretion…”
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3
Untargeted and targeted metabolomics analyses of blackberries – Understanding postharvest red drupelet disorder
Published in Food chemistry (01-12-2019)“…•Metabolomic analyses were employed to characterize red drupelet disorder.•Anthocyanins were significantly lower in red drupelets than in black…”
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4
Danazol Inhibits Cytochrome P450 2J2 Activity in a Substrate-independent Manner
Published in Drug metabolism and disposition (01-08-2015)“…Cytochrome P450 2J2 (CYP2J2) is an enzyme responsible for the metabolism of endogenous substrates including arachidonic acid, as well as therapeutic drugs such…”
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Plasma sphingomyelins increase in pre-diabetic Korean men with abdominal obesity
Published in PloS one (05-03-2019)“…Abdominal or visceral obesity is a well-known risk factor for metabolic diseases. However, whether abdominal obesity significantly affects plasma lipid profile…”
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6
Cooperative interactions between seed-borne bacterial and air-borne fungal pathogens on rice
Published in Nature communications (02-01-2018)“…Bacterial-fungal interactions are widely found in distinct environments and contribute to ecosystem processes. Previous studies of these interactions have…”
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7
Mass spectrometry-based metabolite profiling in the mouse liver following exposure to ultraviolet B radiation
Published in PloS one (02-10-2014)“…Although many studies have been performed on the effects of ultraviolet (UV) radiation on the skin, only a limited number of reports have investigated these…”
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8
Deletion of PHO13 improves aerobic l-arabinose fermentation in engineered Saccharomyces cerevisiae
Published in Journal of industrial microbiology & biotechnology (01-12-2019)“…Pentose sugars are increasingly being used in industrial applications of Saccharomyces cerevisiae. Although l -arabinose is a highlighted pentose that has been…”
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DC23, a Triazolothione Resorcinol Analogue, Is Extensively Metabolized to Glucuronide Conjugates in Human Liver Microsomes
Published in Mass spectrometry letters (30-03-2018)“…DC23, a triazolothione resorcinol analogue, is known to inhibit heat shock protein 90 and pyruvate dehydrogenase kinase which are up-regulated in cancer and…”
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10
Plasma Lipidomics Reveals Insights into Anti-Obesity Effect of Chrysanthemum morifolium Ramat Leaves and Its Constituent Luteolin in High-Fat Diet-Induced Dyslipidemic Mice
Published in Nutrients (29-09-2020)“…The Ramat (CM) is widely used as a traditional medicine and herbal tea by the Asian population for its health benefits related to obesity. However, compared to…”
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11
The green tea modulates large intestinal microbiome and exo/endogenous metabolome altered through chronic UVB-exposure
Published in PloS one (08-11-2017)“…The attenuating effects of green tea supplements (GTS) against the ultraviolet (UV) radiation induced skin damages are distinguished. However, the concomitant…”
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Chrysanthemum Leaf Ethanol Extract Prevents Obesity and Metabolic Disease in Diet-Induced Obese Mice via Lipid Mobilization in White Adipose Tissue
Published in Nutrients (15-06-2019)“…This study aimed to elucidate the molecular mechanism of Ramat. against obesity and diabetes, by comparing the transcriptional changes in epididymal white…”
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13
Crosstalk between TM4SF5 and GLUT8 regulates fructose metabolism in hepatic steatosis
Published in Molecular metabolism (Germany) (01-04-2022)“…Transmembrane 4 L six family member 5 (TM4SF5) is likely involved in non-alcoholic steatohepatitis, although its roles and cross-talks with glucose/fructose…”
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14
Urine and serum metabolite profiling of rats fed a high-fat diet and the anti-obesity effects of caffeine consumption
Published in Molecules (Basel, Switzerland) (13-02-2015)“…In this study, we investigated the clinical changes induced by a high fat diet (HFD) and caffeine consumption in a rat model. The mean body weight of the HFD…”
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15
In Vitro Metabolism Study of Seongsanamide A in Human Liver Microsomes Using Non-Targeted Metabolomics and Feature-Based Molecular Networking
Published in Pharmaceutics (07-07-2021)“…Seongsanamide A is a bicyclic peptide with an isodityrosine residue discovered in Bacillus safensis KCTC 12796BP which exhibits anti-allergic activity in vitro…”
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16
A lipidomic platform establishment for structural identification of skin ceramides with non-hydroxyacyl chains
Published in Analytical and bioanalytical chemistry (01-03-2014)“…The stratum corneum (SC) is the outermost layer of skin that functions as a barrier and protects against environmental influences and transepidermal water…”
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17
Lipidomic platform for structural identification of skin ceramides with [alpha]-hydroxyacyl chains
Published in Analytical and bioanalytical chemistry (01-03-2016)“…Skin ceramides are sphingolipids consisting of sphingoid bases, which are linked to fatty acids via an amide bond. Typical fatty acid acyl chains are composed…”
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18
Screening of non-steroidal anti-inflammatory drugs for inhibitory effects on the activities of six UDP-glucuronosyltransferases (UGT1A1, 1A3, 1A4, 1A6, 1A9 and 2B7) using LC-MS/MS
Published in Biopharmaceutics & drug disposition (01-05-2015)“…Non‐steroidal anti‐inflammatory drugs (NSAIDs) are used widely to relieve pain and to decrease inflammation. Several clinical studies have reported that NSAIDs…”
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DC23, a Triazolothione Resorcinol Analogue, Is Extensively Metabolized to Glucuronide Conjugates in Human Liver Microsomes
Published in Mass spectrometry letters (01-03-2018)“…DC23, a triazolothione resorcinol analogue, is known to inhibit heat shock protein 90 and pyruvate dehydrogenase kinase which are up-regulated in cancer and…”
Get full text
Journal Article -
20
Sphingolipids Modulate Secretion of Glycosylphosphatidylinositol-Anchored Plasmodesmata Proteins and Callose Deposition1
Published in Plant physiology (Bethesda) (07-07-2020)“…Arabidopsis glucosyl sphingolipid-modulated plasmodesmal gating involves modulation of the glycosylphosphatidylinositol-anchored PdBG2 protein secretion…”
Get full text
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