Search Results - "Shome, Bibek R."
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Amide side chain amphiphilic polymers disrupt surface established bacterial bio-films and protect mice from chronic Acinetobacter baumannii infection
Published in Biomaterials (01-01-2016)“…Abstract Bacterial biofilms represent the root-cause of chronic or persistent infections in humans. Gram-negative bacterial infections due to nosocomial and…”
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An Understanding of the Global Status of Major Bacterial Pathogens of Milk Concerning Bovine Mastitis: A Systematic Review and Meta-Analysis (Scientometrics)
Published in Pathogens (Basel) (30-04-2021)“…In this study, the major mastitis pathogen prevalence in the cattle and buffalo of the world was estimated by a meta-analysis. (S) species, (St) species, and…”
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3
Membrane-active macromolecules kill antibiotic-tolerant bacteria and potentiate antibiotics towards Gram-negative bacteria
Published in PloS one (24-08-2017)“…Chronic bacterial biofilms place a massive burden on healthcare due to the presence of antibiotic-tolerant dormant bacteria. Some of the conventional…”
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Aryl-Alkyl-Lysines: Agents That Kill Planktonic Cells, Persister Cells, Biofilms of MRSA and Protect Mice from Skin-Infection
Published in PloS one (15-12-2015)“…Development of synthetic strategies to combat Staphylococcal infections, especially those caused by methicillin resistant Staphyloccus aureus (MRSA), needs…”
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Membrane-active macromolecules resensitize NDM-1 gram-negative clinical isolates to tetracycline antibiotics
Published in PloS one (19-03-2015)“…Gram-negative 'superbugs' such as New Delhi metallo-beta-lactamase-1 (blaNDM-1) producing pathogens have become world's major public health threats…”
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Understanding Antibiotic Usage on Small-Scale Dairy Farms in the Indian States of Assam and Haryana Using a Mixed-Methods Approach—Outcomes and Challenges
Published in Antibiotics (Basel) (18-09-2021)“…The use and misuse of antibiotics in both humans and animals contributes to the global emergence of antimicrobial resistant (AMR) bacteria, a threat to public…”
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Factors Influencing Antibiotic Prescribing Behavior and Understanding of Antimicrobial Resistance Among Veterinarians in Assam, India
Published in Frontiers in veterinary science (26-04-2022)“…This study investigates factors influencing veterinarians' antibiotic prescribing behaviors and their understanding of antimicrobial resistance (AMR). The…”
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Molecular Characterization of Methicillin-Resistant Staphylococci from the Dairy Value Chain in Two Indian States
Published in Pathogens (Basel) (01-02-2023)“…Bovine milk and milk products may contain pathogens, antimicrobial resistant bacteria, and antibiotic residues that could harm consumers. We analyzed 282…”
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Antibiotic use, knowledge, and practices of milk vendors in India's informal dairy value chain
Published in Frontiers in sustainable food systems (30-11-2022)“…Background: Milk vendors play an important role in India's dairy value chain; however, their food safety practices are poorly understood. From the standpoint…”
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Biocompatible Injectable Hydrogel with Potent Wound Healing and Antibacterial Properties
Published in Molecular pharmaceutics (03-04-2017)“…Two component injectable hydrogels that cross-link in situ have been used as noninvasive wound-filling devices, i.e., sealants. These materials carry a variety…”
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Molecular detection and typing of methicillin-resistant Staphylococcus aureus and methicillin-resistant coagulase-negative staphylococci isolated from cattle, animal handlers, and their environment from Karnataka, Southern Province of India
Published in Veterinary World (01-11-2019)“…Methicillin-resistant staphylococci are among the emerging pathogens which have become a threat to both human and animal health. The present investigation…”
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Serological and molecular analysis for brucellosis in selected swine herds from Southern India
Published in Journal of infection and public health (01-03-2019)“…Swine brucellosis is a zoonotic disease caused by Brucella suis. The study describes the occurrence of brucellosis in two organized piggeries in Southern…”
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13
Histone H3K14 and H4K8 hyperacetylation is associated with Escherichia coli-induced mastitis in mice
Published in Epigenetics (01-05-2012)“…Mastitis is a multietiological complex disease, defined as inflammation of parenchyma of mammary glands. Bacterial infection is the predominant cause of…”
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Membrane Disruption and Enhanced Inhibition of Cell-Wall Biosynthesis: A Synergistic Approach to Tackle Vancomycin-Resistant Bacteria
Published in Angewandte Chemie International Edition (09-11-2015)“…Resistance to glycopeptide antibiotics, the drugs of choice for life‐threatening bacterial infections, is on the rise. In order to counter the threat of…”
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Occurrence and characterization of genetic determinants of β-lactam-resistance in Escherichia coli clinical isolates
Published in Infection, genetics and evolution (01-06-2022)“…β-lactamase mediated resistance in Escherichia coli is a significant problem that requires immediate attention. Herein, we aim to characterize and understand…”
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Chitosan Derivatives Active against Multidrug-Resistant Bacteria and Pathogenic Fungi: In Vivo Evaluation as Topical Antimicrobials
Published in Molecular pharmaceutics (03-10-2016)“…The continuous rise of antimicrobial resistance and the dearth of new antibiotics in the clinical pipeline raise an urgent call for the development of potent…”
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Understanding policy dilemmas around antibiotic use in food animals & offering potential solutions
Published in Indian journal of medical research (New Delhi, India : 1994) (01-02-2019)“…The looming concern of antimicrobial resistance (AMR) has prompted the government of many countries of the world to act upon and come up with the guidelines,…”
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Side Chain Degradable Cationic–Amphiphilic Polymers with Tunable Hydrophobicity Show in Vivo Activity
Published in Biomacromolecules (12-09-2016)“…Cationic–amphiphilic antibacterial polymers with optimal amphiphilicity generally target the bacterial membranes instead of mammalian membranes. To date, this…”
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Resistance profiles and genotyping of extended-spectrum beta-lactamase (ESBL) -producing and non-ESBL-producing E. coli and Klebsiella from retail market fishes
Published in Infection, genetics and evolution (01-08-2023)“…Studies on antimicrobial resistance (AMR) profiles and epidemiological affirmation for AMR transmission are limited in fisheries and aquaculture settings…”
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Genomic insights of beta-lactamase producing Klebsiella quasipneumoniae subsp. similipneumoniae belonging to sequence type 1699 from retail market fish, India
Published in Archives of microbiology (01-08-2022)“…Klebsiella quasipneumoniae is a recently described species and often misidentified as Klebsiella pneumoniae . Here, we report the genomic characterization of…”
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