Search Results - "Shokry, Doha"

Reciprocal epigenetic remodeling controls testicular cancer hypersensitivity to hypomethylating agents and chemotherapy by Singh, Ratnakar, Fazal, Zeeshan, Bikorimana, Emmanuel, Boyd, Raya I., Yerby, Cliff, Tomlin, Megan, Baldwin, Hannah, Shokry, Doha, Corbet, Andrea K., Shahid, Khadeeja, Hattab, Aleyah, Freemantle, Sarah J., Spinella, Michael J.

“…Testicular germ cell tumors (TGCTs) are aggressive but sensitive to cisplatin‐based chemotherapy. Alternative therapies are needed for tumors refractory to…”
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Refractory testicular germ cell tumors are highly sensitive to the targeting of polycomb pathway demethylases KDM6A and KDM6B by Shokry, Doha, Khan, Mehwish W, Powell, Christine, Johnson, Samantha, Rennels, Brayden C, Boyd, Raya I, Sun, Zhengyang, Fazal, Zeeshan, Freemantle, Sarah J, Parker, Maryanna H, Vieson, Miranda D, Samuelson, Jonathan P, Spinella, Michael J, Singh, Ratnakar

“…Testicular germ cell tumors (TGCTs) can be treated with cisplatin-based therapy. However, a clinically significant number of cisplatin-resistant patients die…”
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G0S2 promotes antiestrogenic and pro-migratory responses in ER+ and ER- breast cancer cells by Corbet, Andrea K., Bikorimana, Emmanuel, Boyd, Raya I., Shokry, Doha, Kries, Kelly, Gupta, Ayush, Paton, Anneliese, Sun, Zhengyang, Fazal, Zeeshan, Freemantle, Sarah J., Nelson, Erik R., Spinella, Michael J., Singh, Ratnakar

“…•G0S2 has a complex role in breast cancer, dependent on ER status and partially mediated by suppression of estrogen signaling pathways.•Overexpression of G0S2…”
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Perfluorooctanesulfonic Acid Alters Pro-Cancer Phenotypes and Metabolic and Transcriptional Signatures in Testicular Germ Cell Tumors by Boyd, Raya I, Shokry, Doha, Fazal, Zeeshan, Rennels, Brayden C, Freemantle, Sarah J, La Frano, Michael R, Prins, Gail S, Madak Erdogan, Zeynep, Irudayaraj, Joseph, Singh, Ratnakar, Spinella, Michael J

“…The potential effects of poly- and perfluoroalkyl substances (PFAS) are a recently emergent human and environmental health concern. There is a consistent link…”
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Abstract 2096: Genome wide remodeling of DNA methylation and CpG hypermethylation is tightly linked to acquired resistance in testicular cancer by Fazal, Zeeshan, Singh, Ratnakar, Tomlin, Megan, Shokry, Doha, Hattab, Aleyah, Spinella, Sarah, Spinella, Michael

“…Abstract Acquired resistance to chemotherapy is perhaps the major barrier to cure of advanced cancers. Testicular germ cell tumors (TGCTs) are the most common…”
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Abstract 2127: Polycomb signaling reciprocally regulates sensitivity of testicular germ cell tumors cells to cisplatin and DNA hypomethylating agents by Singh, Ratnakar, Bikorimana, Emmanuel, Fazal, Zeeshan, Yerby, Cliff, Baldwin, Hannah, Hattab, Aleyah Destiny, Tomlin, Megan, Corbet, Andrea K., Boyd, Raya Iman, Shahid, Khadeeja, Shokry, Doha Naguib Ahmed Mohamed, Spinella, Sarah Joy, Spinella, Michael J.

“…Abstract Testicular germ cell tumors (TGCTs) are the most frequent solid cancers of males between the ages of 16 to 39 and have the highest mortality in this…”
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Abstract 7208: Targeting histone demethylase KDM6B to overcome cisplatin resistance in testicular germ cell tumors by Singh, Ratnakar, Shokry, Doha, Boyd, Raya I., Rennels, Brayden C., Powell, Christine, Kahn, Mehwish, Freemantle, Sarah J., Spinella, Michael J.

“…Abstract Testicular germ cell tumors (TGCTs) represent the most common carcinoma of young men and are believed to arise from the transformation of primordial…”
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Abstract 4561: Mechanism of histone H3K27me3 demethylase therapy for restoring cisplatin sensitivity in refractory testicular cancer by Shokry, Doha Naguib Ahmed Mohamed, Singh, Ratnakar, Khan, Mehwish, Fazal, Zeeshan, Boyd, Raya, Powell, Christine, Freemantle, Sarah J., Spinella, Michael J.

“…Abstract Testicular germ cell tumors (TGCTs) can be cured at a high rate with standard cisplatin-based chemotherapy, but 15% of metastatic patients are…”
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Post-Hatching Development of the Chicken Ovary (Alexandria breed) by Shokry, Doha, Amin, Mohamed, Karkoura, Ashraf, Alsafy, Mohamed, ElGendy, Samir

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