Search Results - "Shoji, Takao"

Synthesis of Azanucleosides by Anodic Oxidation in a Lithium Perchlorate–Nitroalkane Medium and Diversification at the 4′‐Nitrogen Position by Shoji, Takao, Kim, Shokaku, Chiba, Kazuhiro

“…Azanucleosides, in which the 4′‐oxygen atom has been replaced with a nitrogen atom, have drawn much attention owing to their anticancer and antivirus activity,…”
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Synthesis of Ribo‐Azanucleosides by Anodic Oxidation: Reactivity Control of Intermediate for Efficient Access to Pharmacophores by Okamoto, Kazuhiro, Shoji, Takao, Tsutsui, Mizuki, Shida, Naoki, Chiba, Kazuhiro

“…Azanucleosides, the sugar‐modified nucleoside analogues, have various biological activities, while their efficient synthetic strategy is still under…”
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Synthetic Method for Oligonucleotide Block by Using Alkyl-Chain-Soluble Support by Matsuno, Yuki, Shoji, Takao, Kim, Shokaku, Chiba, Kazuhiro

“…A straightforward method for the synthesis of oligonucleotide blocks using a Cbz-type alkyl-chain-soluble support (Z-ACSS) attached to the 3′-OH group of…”
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Development of an exon skipping therapy for X-linked Alport syndrome with truncating variants in COL4A5 by Yamamura, Tomohiko, Horinouchi, Tomoko, Adachi, Tomomi, Terakawa, Maki, Takaoka, Yutaka, Omachi, Kohei, Takasato, Minoru, Takaishi, Kiyosumi, Shoji, Takao, Onishi, Yoshiyuki, Kanazawa, Yoshito, Koizumi, Makoto, Tomono, Yasuko, Sugano, Aki, Shono, Akemi, Minamikawa, Shogo, Nagano, China, Sakakibara, Nana, Ishiko, Shinya, Aoto, Yuya, Kamura, Misato, Harita, Yutaka, Miura, Kenichiro, Kanda, Shoichiro, Morisada, Naoya, Rossanti, Rini, Ye, Ming Juan, Nozu, Yoshimi, Matsuo, Masafumi, Kai, Hirofumi, Iijima, Kazumoto, Nozu, Kandai

“…Currently, there are no treatments for Alport syndrome, which is the second most commonly inherited kidney disease. Here we report the development of an…”
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Development of anodic modification reaction of N-acryloyl-proline derivatives using lithium perchlorate-nitromethane system by Shoji, Takao, Haraya, Suzuna, Kim, Shokaku, Chiba, Kazuhiro

“…[Display omitted] A facile electrochemical method for modification of the 5-position in N-acryloyl-proline methyl ester (N-Acr-Pro-OMe), followed by…”
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Electrochemical synthesis of azanucleoside derivatives using a lithium perchlorate-nitromethane system by Kim, Shokaku, Shoji, Takao, Kitano, Yoshikazu, Chiba, Kazuhiro

“…We have developed a highly efficient synthetic method for azanucleosides using a lithium perchlorate-nitromethane reaction medium, allowing direct and…”
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Anodic Substitution Reaction of Proline Derivatives Using the 2,4,6-Trimethoxyphenyl Leaving Group by Shoji, Takao, Kim, Shokaku, Yamamoto, Keisuke, Kawai, Tomomitsu, Okada, Yohei, Chiba, Kazuhiro

“…An efficient method for modifying a proline moiety through anodic carbon–carbon bond cleavage is developed. Use of the 2,4,6-trimethoxyphenyl (TMP) moiety as a…”
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Artificial bioconjugates with naturally occurring linkages: the use of phosphodiester by Shoji, Takao, Fukutomi, Hiroki, Okada, Yohei, Chiba, Kazuhiro

“…Artificial orthogonal bond formations such as the alkyne-azide cycloaddition have enabled selective bioconjugations under mild conditions, yet naturally…”
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Synthesis of Conjugated Oligonucleotide in Solution Phase Using Alkyl-chain-soluble Support by Shoji, Takao, Kim, Shokaku, Chiba, Kazuhiro

“…Conjugated oligonucleotides attract interest from various areas such as medicine and nanotechnology. Common synthetic methods, however, rely on heterogeneous…”
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Encapsulating peritoneal sclerosis in Japan: A prospective, controlled, multicenter study by Kawanishi, Hideki, Kawaguchi, Yoshindo, Fukui, Hiroyoshi, Hara, Shigeko, Imada, Akio, Kubo, Hitoshi, Kin, Masao, Nakamoto, Masahiko, Ohira, Seiji, Shoji, Takao

“…Background: Encapsulating peritoneal sclerosis (EPS) is recognized as a rare but serious complication of peritoneal dialysis (PD). The aim of this study was to…”
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Synthesis of Azanucleosides by Anodic Oxidation in a Lithium Perchlorate–Nitroalkane Medium and Diversification at the 4′‐Nitrogen Position by Shoji, Takao, Kim, Shokaku, Chiba, Kazuhiro

“…Azanucleosides, in which the 4′‐oxygen atom has been replaced with a nitrogen atom, have drawn much attention owing to their anticancer and antivirus activity,…”
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Evaluating the Knockdown Activity of MALAT1 ENA Gapmers In Vitro by Iwashita, Shinzo, Shoji, Takao, Koizumi, Makoto

“…Antisense oligonucleotides (ASOs) are widely used for the identification of gene functions and regulation of genes involved in different diseases for…”
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Encapsulating peritoneal sclerosis in Japan: A prospective, controlled, multicenter study by KAWANISHI, Hideki, KAWAGUCHI, Yoshindo, FUKUI, Hiroyoshi, HARA, Shigeko, IMADA, Akio, KUBO, Hitoshi, KIN, Masao, NAKAMOTO, Masahiko, OHIRA, Seiji, SHOJI, Takao

“…Encapsulating peritoneal sclerosis (EPS) is recognized as a rare but serious complication of peritoneal dialysis (PD). The aim of this study was to determine…”
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P3-086 Exploration of possible solvents or administration route to assess water-insoluble drugs in halothane-anesthetized guinea-pig model by Yasue Sakaguchi, Akira Takahara, Sachiko Honsho, Shoji Takao, Atsushi Sugiyama

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Encapsulating peritoneal sclerosis in Japan: prospective multicenter controlled study by Kawanishi, H

“…Encapsulating peritoneal sclerosis (EPS) is recognized as a serious complication of peritoneal dialysis. The aim of this study was to determine the incidence,…”
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Underlying Genetic Causes of Adult Patients With ESKD Undergoing Hemodialysis Therapy: SA-PO549 by Fujimaru, Takuya, Mori, Takayasu, Chiga, Motoko, Mandai, Shintaro, Ando, Fumiaki, Mori, Yutaro, Susa, Koichiro, Nakano, Yuta, Shoji, Takao, Fukudome, Yuichiro, Inaba, Naoto, Kitamura, Kenichiro, Nakanishi, Taichi, Kimura, Toshihiro, Tamura, Teiichi, Ozawa, Kiyoshi, Uchida, Shinichi, Sohara, Eisei

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Genetic Diagnosis of Adult Hemodialysis Patients With Unknown Etiology by Fujimaru, Takuya, Mori, Takayasu, Chiga, Motoko, Mandai, Shintaro, Kikuchi, Hiroaki, Ando, Fumiaki, Mori, Yutaro, Susa, Koichiro, Nakano, Yuta, Shoji, Takao, Fukudome, Yuichiro, Inaba, Naoto, Kitamura, Kenichiro, Nakanishi, Taichi, Uchida, Keiko, Kimura, Toshihiro, Tamura, Teiichi, Ozawa, Kiyoshi, Uchida, Shinichi, Sohara, Eisei

“…Kidney disease of unknown etiology accounts for 1 in 10 adult end-stage renal disease (ESRD) cases worldwide. The aim of this study is to clarify the genetic…”
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Health-related quality of life of predialysis patients with chronic renal failure by Fukuhara, Shunichi, Yamazaki, Shin, Marumo, Fumiaki, Akiba, Takashi, Akizawa, Tadao, Fujimi, Satoru, Haruki, Shigekazu, Kawaguchi, Yoshindo, Nihei, Hiroshi, Shoji, Takao, Maeda, Teiryou

“…Health-related quality of life (HQOL) of predialysis patients with chronic renal failure (CRF) has received less attention than that of dialysis patients. We…”
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Ten years' survey of dialysis-associated tuberculosis by Sasaki, S, Akiba, T, Suenaga, M, Tomura, S, Yoshiyama, N, Nakagawa, S, Shoji, T, Sasaoka, T, Takeuchi, J

“…Tuberculosis associated with dialysis was studied at the Renal Unit of the Tokyo Medical and Dental University and Yokosuka Mutual Aid Hospital Kidney Center,…”
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Darbepoetin Alfa (KRN321) Administered Intravenously Once Monthly Maintains Hemoglobin Levels in Peritoneal Dialysis Patients by Hiramatsu, Makoto, Kubota, Minoru, Iwasaki, Manabu, Akizawa, Tadao, Koshikawa, Shozo

“…:  Darbepoetin alfa (KRN321) is a novel molecule that stimulates erythropoiesis by the same mechanism as endogenous erythropoietin. Due to its longer half‐life…”
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