Search Results - "Shoffstall, Andrew J."
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Efficacy of bone stimulators in large-animal models and humans may be limited by weak electric fields reaching fracture
Published in Scientific reports (16-12-2022)“…Noninvasive electronic bone growth stimulators (EBGSs) have been in clinical use for decades. However, systematic reviews show inconsistent and limited…”
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Imaging peripheral nerve micro-anatomy with MUSE, 2D and 3D approaches
Published in Scientific reports (17-06-2022)“…Understanding peripheral nerve micro-anatomy can assist in the development of safe and effective neuromodulation devices. However, current approaches for…”
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Deep-learning segmentation of fascicles from microCT of the human vagus nerve
Published in Frontiers in neuroscience (10-05-2023)“…MicroCT of the three-dimensional fascicular organization of the human vagus nerve provides essential data to inform basic anatomy as well as the development…”
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The High Direct Medical Costs of Prader-Willi Syndrome
Published in The Journal of pediatrics (01-08-2016)“…Objective To assess medical resource utilization associated with Prader-Willi syndrome (PWS) in the US, hypothesized to be greater relative to a matched…”
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In vivo Visualization of Pig Vagus Nerve "Vagotopy" Using Ultrasound
Published in Frontiers in neuroscience (25-11-2021)“…Placement of the clinical vagus nerve stimulating cuff is a standard surgical procedure based on anatomical landmarks, with limited patient specificity in…”
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Electronic Bone Growth Stimulators for Augmentation of Osteogenesis in In Vitro and In Vivo Models: A Narrative Review of Electrical Stimulation Mechanisms and Device Specifications
Published in Frontiers in bioengineering and biotechnology (14-02-2022)“…Since the piezoelectric quality of bone was discovered in 1957, scientists have applied exogenous electrical stimulation for the purpose of healing. Despite…”
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Understanding the Effects of Both CD14-Mediated Innate Immunity and Device/Tissue Mechanical Mismatch in the Neuroinflammatory Response to Intracortical Microelectrodes
Published in Frontiers in neuroscience (31-10-2018)“…Intracortical microelectrodes record neuronal activity of individual neurons within the brain, which can be used to bridge communication between the biological…”
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Electrical Stimulation of Acute Fractures: A Narrative Review of Stimulation Protocols and Device Specifications
Published in Frontiers in bioengineering and biotechnology (02-06-2022)“…Orthopedic fractures have a significant impact on patients in the form of economic loss and functional impairment. Beyond the standard methods of reduction and…”
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Correction: The role of spinal cord neuroanatomy in the variances of epidural spinal recordings
Published in Bioelectronic medicine (07-08-2024)Get full text
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Characterization of the Neuroinflammatory Response to Thiol-ene Shape Memory Polymer Coated Intracortical Microelectrodes
Published in Micromachines (Basel) (24-09-2018)“…Thiol-ene based shape memory polymers (SMPs) have been developed for use as intracortical microelectrode substrates. The unique chemistry provides precise…”
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Augmented Transcutaneous Stimulation Using an Injectable Electrode: A Computational Study
Published in Frontiers in bioengineering and biotechnology (20-12-2021)“…Minimally invasive neuromodulation technologies seek to marry the neural selectivity of implantable devices with the low-cost and non-invasive nature of…”
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Dexamethasone eluting polydopaminated polycaprolactone‐poly (lactic‐co‐glycolic) acid for treatment of tracheal stenosis
Published in Journal of biomedical materials research. Part A (01-05-2024)“…Tracheal stenosis is commonly caused by injury, resulting in inflammation and fibrosis. Inhibiting inflammation and promoting epithelization can reduce…”
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Cyclodextrin-based device coatings for affinity-based release of antibiotics
Published in Biomaterials (01-03-2010)“…Abstract Cyclodextrin-based hydrogels were synthesized to create robust networks with tunable mechanical properties capable of serving as device coatings. The…”
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A Mosquito Inspired Strategy to Implant Microprobes into the Brain
Published in Scientific reports (09-01-2018)“…Mosquitos are among the deadliest insects on the planet due to their ability to transmit diseases like malaria through their bite. In order to bite, a mosquito…”
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Biodistribution, pharmacokinetics, and blood compatibility of native and PEGylated tobacco mosaic virus nano-rods and -spheres in mice
Published in Virology (New York, N.Y.) (20-01-2014)“…Abstract Understanding the pharmacokinetics, blood compatibility, biodistribution and clearance properties of nanoparticles is of great importance to their…”
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Platelets and hemostatic proteins are co-localized with chronic neuroinflammation surrounding implanted intracortical microelectrodes
Published in Acta biomaterialia (01-08-2023)“…Intracortical microelectrodes induce vascular injury upon insertion into the cortex. As blood vessels rupture, blood proteins and blood-derived cells…”
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Microelectrode implantation in motor cortex causes fine motor deficit: Implications on potential considerations to Brain Computer Interfacing and Human Augmentation
Published in Scientific reports (10-11-2017)“…Intracortical microelectrodes have shown great success in enabling locked-in patients to interact with computers, robotic limbs, and their own electrically…”
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Neuron-like neural probes
Published in Nature materials (01-05-2019)“…Neural probes that mimic the subcellular structural features and mechanical properties of neurons assimilate across several structures of the brain to provide…”
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Advances in Injectable Polymeric Biomaterials and Their Contemporary Medical Practices
Published in ACS applied bio materials (29-10-2024)“…Injectable biomaterials have been engineered to operate within the human body, offering versatile solutions for minimally invasive therapies and meeting…”
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