Search Results - "Shoemaker, James T."

Validation of a 3D perfused cell culture platform as a tool for humanised preclinical drug testing in breast cancer using established cell lines and patient-derived tissues by Liu, Peng, Roberts, Sophie, Shoemaker, James T, Vukasinovic, Jelena, Tomlinson, Darren C, Speirs, Valerie

“…3D cell culture models of cancer are currently being developed to recapitulate in vivo physiological conditions and to assess therapeutic responses. However,…”
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The effect of conditional inactivation of beta 1 integrins using twist 2 Cre, Osterix Cre and osteocalcin Cre lines on skeletal phenotype by Shekaran, Asha, Shoemaker, James T, Kavanaugh, Taylor E, Lin, Angela S, LaPlaca, Michelle C, Fan, Yuhong, Guldberg, Robert E, García, Andrés J

“…Abstract Skeletal development and growth are complex processes regulated by multiple microenvironmental cues, including integrin–ECM interactions. The β1…”
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A 3D Cell Culture Organ-on-a-Chip Platform With a Breathable Hemoglobin Analogue Augments and Extends Primary Human Hepatocyte Functions in vitro by Shoemaker, James T., Zhang, Wanrui, Atlas, Selin I., Bryan, Richard A., Inman, S. Walker, Vukasinovic, Jelena

“…Remarkable advances in three-dimensional (3D) cell cultures and organ-on-a-chip technologies have opened the door to recapitulate complex aspects of human…”
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SeedEZTM Interdigitated Electrodes and Multifunctional Layered Biosensor Composites (MLBCs): A Paradigm Shift in the Development of In Vitro BioMicrosystems by Didier, Charles Michael, Kundu, Avra, Shoemaker, James T., Vukasinovic, Jelena, Rajaraman, Swaminathan

“…We developed a new technology for the realization of composite biosensor systems, capable of measuring electrical and electrophysiological signals from…”
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From animal testing to in vitro systems: advancing standardization in microphysiological systems by Reyes, Darwin R, Esch, Mandy B, Ewart, Lorna, Nasiri, Rohollah, Herland, Anna, Sung, Kyung, Piergiovanni, Monica, Lucchesi, Carolina, Shoemaker, James T, Vukasinovic, Jelena, Nakae, Hiroki, Hickman, James, Pant, Kapil, Taylor, Anne, Heinz, Niki, Ashammakhi, Nureddin

“…Limitations with cell cultures and experimental animal-based studies have had the scientific and industrial communities searching for new approaches that can…”
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SeedEZ™ Interdigitated Electrodes and Multifunctional Layered Biosensor Composites (MLBCs): A Paradigm Shift in the Development of In Vitro BioMicrosystems by Didier, Charles M, Kundu, Avra, Shoemaker, James T, Vukasinovic, Jelena, Rajaraman, Swaminathan

“…We have developed a new technology for the realization of composite biosensor systems, capable of measuring electrical and electrophysiological signals from…”
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Protease-degradable PEG-maleimide coating with on-demand release of IL-1Ra to improve tissue response to neural electrodes by Gutowski, Stacie M, Shoemaker, James T, Templeman, Kellie L, Wei, Yang, Latour, Robert A, Bellamkonda, Ravi V, LaPlaca, Michelle C, García, Andrés J

“…Abstract Neural electrodes are an important part of brain-machine interface devices that can restore functionality to patients with sensory and movement…”
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The Lipoprotein Receptor LR11 Regulates Amyloid beta Production and Amyloid Precursor Protein Traffic in Endosomal Compartments by Offe, Katrin, Dodson, Sara E, Shoemaker, James T, Fritz, Jason J, Gearing, Marla, Levey, Allan I, Lah, James J

“…Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive cognitive decline and neuropathological changes, including the deposition…”
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Host response to microgel coatings on neural electrodes implanted in the brain by Gutowski, Stacie M., Templeman, Kellie L., South, Antoinette B., Gaulding, Jeffrey C., Shoemaker, James T., LaPlaca, Michelle C., Bellamkonda, Ravi V., Lyon, L. Andrew, García, Andrés J.

“…The performance of neural electrodes implanted in the brain is often limited by host response in the surrounding brain tissue, including astrocytic scar…”
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Stimulus-evoked high frequency oscillations are present in neuronal networks on microelectrode arrays by Hales, Chadwick M, Zeller-Townson, Riley, Newman, Jonathan P, Shoemaker, James T, Killian, Nathan J, Potter, Steve M

“…Pathological high frequency oscillations (250-600 Hz) are present in the brains of epileptic animals and humans. The etiology of these oscillations and how…”
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Abstract 4080: Cytochrome P450 enzyme activity is enhanced in hepatocytes grown using a perfused 3D cell culture drug screening system by Shoemaker, James T., Vukasinovic, Jelena

“…A critical requirement for assessing drug toxicity in vitro is cytochrome P450 (CYP) function that is physiologically representative. Due to low levels of CYP…”
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SeedEZ TM Interdigitated Electrodes and Multifunctional Layered Biosensor Composites (MLBCs): A Paradigm Shift in the Development of In Vitro BioMicrosystems by Didier, Charles Michael, Kundu, Avra, Shoemaker, James T., Vukasinovic, Jelena, Rajaraman, Swaminathan

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Abstract 54: Characterization of patient-derived organoids cultured on a gas-rich, liquid-liquid interface by Shoemaker, James T., Richardson, Katherine R., Arnst, Jamie, Marcus, Adam, Vukasinovic, Jelena

“…Modeling tissues in vitro has long consisted of two-dimensional (2D) monolayer cultures grown in a dish, flask, or multi-well plate. While these methods remain…”
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Stimulus induced high frequency oscillations are present in neuronal networks on microelectrode arrays by Chadwick M Hales, Chadwick M Hales, Riley eZeller-Townson, Jonathan P Newman, James T Shoemaker, Nathan J Killian, Steve M Potter

“…Pathological high frequency oscillations (250-600Hz) are present in the brains of epileptic animals and humans. The etiology of these oscillations and how they…”
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P4-143: Identification of the apoe receptor sorLA/LR11 as a novel component of hallmark Alzheimer’s disease-related lesions in down syndrome by Khoogar, Leila, Dodson, Sara E., Shoemaker, James T., Rees, Howard D., Mufson, Elliot, Levey, Allan I., Lah, James J.

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P3-303 Examining the role of the APOE receptor LR11 in the etiopathology of Alzheimer's disease by Dodson, Sara E., Offe, Katrin, Carter, Stephanie C., Shoemaker, James T., Fang, Guofu, Lah, James J., Levey, Allan I.

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Experiential Versus Didactic Training of Teacher Behaviors by Shoemaker, James T

“…The purpose of this study was to compare the effectiveness of two methods of instruction, experiential training and didactic training, in facilitating the…”
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A Competency-Based Model for Counselor Certification by Shoemaker, James T, Splitter, Jackie L

“…The state of Washington has recently begun several state-wide competency-based certification programs. These programs are being used to evaluate school…”
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