Search Results - "Shoemaker, Ashley H."

Hypothalamic Obesity: Prologue and Promise by Abuzzahab, M Jennifer, Roth, Christian L, Shoemaker, Ashley H

“…Hypothalamic obesity (HO) frequently occurs following damage to the medial hypothalamic region, encompassing the arcuate nucleus, the paraventricular nucleus,…”
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Nonclassic features of pseudohypoparathyroidism type 1A by Shoemaker, Ashley H, Jüppner, Harald

“…To provide readers with a review of contemporary literature describing the evolving understanding of the pseudohypoparathyroidism type 1A (PHP1A) phenotype…”
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Prevalence of genetic causes of obesity in clinical practice by Tamaroff, Jaclyn, Williamson, Dylan, Slaughter, James C, Xu, Meng, Srivastava, Gitanjali, Shoemaker, Ashley H

“…While obesity is common in the United States, monogenic obesity is rare, accounting for approximately 5% of individuals with obesity. New targeted therapies…”
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A multidisciplinary approach to the clinical management of Prader–Willi syndrome by Duis, Jessica, van Wattum, Pieter J., Scheimann, Ann, Salehi, Parisa, Brokamp, Elly, Fairbrother, Laura, Childers, Anna, Shelton, Althea Robinson, Bingham, Nathan C., Shoemaker, Ashley H., Miller, Jennifer L.

“…Background Prader–Willi syndrome (PWS) is a complex neuroendocrine disorder affecting approximately 1/15,000–1/30,000 people. Unmet medical needs of…”
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Obstructive Sleep Apnea and Otolaryngologic Manifestations in Children with Pseudohypoparathyroidism by Curley, Kathleen L, Kahanda, Sachini, Perez, Katia M, Malow, Beth A, Shoemaker, Ashley H

“…Pseudohypoparathyroidism (PHP) is a rare, genetic disorder. Patients with PHP may have increased prevalence of obstructive sleep apnea (OSA) but this has not…”
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Approach to the Patient With Hypothalamic Obesity by Shoemaker, Ashley H, Tamaroff, Jaclyn

“…Abstract Hypothalamic obesity (HO) is defined as abnormal weight gain due to physical destruction of the hypothalamus. Suprasellar tumors, most commonly…”
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Turning back the clock by Shoemaker, Ashley H

“…Increased DNA breaks in aging skeletal muscle activate the DNA-PK pathway, whereas blocking this pathway improves mitochondrial density, physical fitness, body…”
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A phase 3 randomized clinical trial using a once‐weekly glucagon‐like peptide‐1 receptor agonist in adolescents and young adults with hypothalamic obesity by Roth, Christian L., Perez, Francisco A., Whitlock, Kathryn B., Elfers, Clinton, Yanovski, Jack A., Shoemaker, Ashley H., Abuzzahab, M. Jennifer

“…Aim To evaluate the efficacy, safety and tolerability of a glucagon‐like peptide‐1 receptor agonist (GLP‐1 RA) in patients with hypothalamic obesity (HO)…”
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A 52‐week pilot study of the effects of exenatide on body weight in patients with hypothalamic obesity by Lomenick, Jefferson P., Buchowski, Maciej S., Shoemaker, Ashley H.

“…Objective Hypothalamic obesity (HO) is a common complication of hypothalamic tumors, and effective therapies are lacking. The objective of this pilot study was…”
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Risk Factors for Progression to Type 2 Diabetes in a Pediatric Prediabetes Clinic Population by Belsky, Natasha, Tamaroff, Jaclyn, Shoemaker, Ashley H

“…Abstract Background Pediatric type 2 diabetes (T2D) is increasing in prevalence, yet it is unclear what definition of pediatric prediabetes predicts…”
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The Coronavirus Disease 2019 Pandemic is Associated with a Substantial Rise in Frequency and Severity of Presentation of Youth-Onset Type 2 Diabetes by Magge, Sheela N., Wolf, Risa M., Pyle, Laura, Brown, Elizabeth A., Benavides, Valeria C., Bianco, Monica E., Chao, Lily C., Cymbaluk, Anna, Balikcioglu, Pinar Gumus, Halpin, Kelsee, Hsia, Daniel S., Huerta-Saenz, Lina, Kim, Jane J., Kumar, Seema, Levitt Katz, Lorraine E., Marks, Brynn E., Neyman, Anna, O'Sullivan, Katie L., Pillai, Sabitha Sasidharan, Shah, Amy S., Shoemaker, Ashley H., Siddiqui, Juwairriyyah A.W., Srinivasan, Shylaja, Thomas, Inas H., Tryggestad, Jeanie B., Yousif, Maha F., Kelsey, Megan M.

“…To evaluate the frequency and severity of new cases of youth-onset type 2 diabetes in the US during the first year of the pandemic compared with the mean of…”
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Setmelanotide for the treatment of acquired hypothalamic obesity: a phase 2, open-label, multicentre trial by Roth, Christian L, Scimia, Cecilia, Shoemaker, Ashley H, Gottschalk, Michael, Miller, Jennifer, Yuan, Guojun, Malhotra, Sonali, Abuzzahab, M Jennifer

“…Hypothalamic obesity resulting from hypothalamic damage might affect melanocortin signalling. We investigated the melanocortin-4 receptor agonist setmelanotide…”
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Trends in pediatric obesity management, a survey from the Pediatric Endocrine Society Obesity Committee by Shoemaker, Ashley H, Chung, Stephanie T, Fleischman, Amy

“…Background In the United States, 18.5% of children are obese. Dietary and lifestyle modifications are key, but often ineffective. There are limited approved…”
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Prolonged lapses between pediatric and adult care are associated with rise in HbA1c and inpatient days among patients with type 1 diabetes by Tilden, Daniel R., French, Benjamin, Shoemaker, Ashley H., Corathers, Sarah, Jaser, Sarah S.

“…•Delays in pediatric-to-adult care transfer were associated with worsening glycemic control among young adults with T1D..•Delays in pediatric-to-adult care…”
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Racial and Ethnic Disparities in Comorbidities in Youth With Type 2 Diabetes in the Pediatric Diabetes Consortium (PDC) by Bacha, Fida, Cheng, Peiyao, Gal, Robin L, Beaulieu, Lindsey C, Kollman, Craig, Adolph, Anne, Shoemaker, Ashley H, Wolf, Risa, Klingensmith, Georgeanna J, Tamborlane, William V

“…Type 2 diabetes in the U.S. is more prevalent in youth of minority racial-ethnic background, but disparities in health outcomes have not been examined in this…”
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Energy balance in hypothalamic obesity in response to treatment with a once-weekly GLP-1 receptor agonist by Shoemaker, Ashley H., Silver, Heidi J., Buchowski, Maciej, Slaughter, James C., Yanovski, Jack A., Elfers, Clinton, Roth, Christian L., Abuzzahab, M. Jennifer

“…Background/Objectives Hypothalamic obesity (HO) frequently occurs following suprasellar tumors from a combination of decreased energy expenditure and increased…”
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MRI measures of hypothalamic injury are associated with glucagon‐like peptide‐1 receptor agonist treatment response in people with hypothalamic obesity by Perez, Francisco A., Elfers, Clinton, Yanovski, Jack A., Shoemaker, Ashley H., Abuzzahab, M. Jennifer, Roth, Christian L.

“…Aim To evaluate whether neuroimaging‐delineated regions of hypothalamic injury are associated with a differential treatment response to a glucagon‐like…”
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Glucose homeostasis and energy balance in children with pseudohypoparathyroidism by Perez, Katia M, Curley, Kathleen L, Slaughter, James C, Shoemaker, Ashley H

“…Pseudohypoparathyroidism (PHP) is a rare genetic disorder characterized by early-onset obesity and multihormone resistance. To treat abnormal weight gain and…”
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Diazoxide Choline Extended-Release Tablet in People With Prader-Willi Syndrome: A Double-Blind, Placebo-Controlled Trial by Miller, Jennifer L, Gevers, Evelien, Bridges, Nicola, Yanovski, Jack A, Salehi, Parisa, Obrynba, Kathryn S, Felner, Eric I, Bird, Lynne M, Shoemaker, Ashley H, Angulo, Moris, Butler, Merlin G, Stevenson, David, Abuzzahab, Jennifer, Barrett, Timothy, Lah, Melissa, Littlejohn, Elizabeth, Mathew, Verghese, Cowen, Neil M, Bhatnagar, Anish

“…Abstract Context Prader-Willi syndrome (PWS) is a rare neurobehavioral-metabolic disease caused by the lack of paternally expressed genes in the chromosome…”
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The Efficacy, Safety, and Pharmacology of a Ghrelin O-Acyltransferase Inhibitor for the Treatment of Prader-Willi Syndrome by Miller, Jennifer L, Lacroix, André, Bird, Lynne M, Shoemaker, Ashley H, Haqq, Andrea, Deal, Cheri L, Clark, Kristie A, Ames, Michael H, Suico, Jeffrey G, de la Peña, Amparo, Fortier, Caroline

“…Acylated ghrelin (AG) stimulates appetite and is elevated compared to its unacylated (UAG) counterpart in Prader-Willi syndrome (PWS). GLWL-01 is a selective,…”
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