Search Results - "Shockley, Samantha E"

Enantioselective Synthesis of Vicinal All‐Carbon Quaternary Centers via Iridium‐Catalyzed Allylic Alkylation by Hethcox, J. Caleb, Shockley, Samantha E., Stoltz, Brian M.

“…The development of the first enantioselective transition‐metal‐catalyzed allylic alkylation providing access to acyclic products bearing vicinal all‐carbon…”
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Enantioselective Iridium-Catalyzed Allylic Alkylation Reactions of Masked Acyl Cyanide Equivalents by Hethcox, J. Caleb, Shockley, Samantha E, Stoltz, Brian M

“…The first enantioselective iridium-catalyzed allylic alkylation reaction of a masked acyl cyanide (MAC) reagent has been developed. The transformation allows…”
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A Catalytic, Enantioselective Formal Synthesis of (+)-Dichroanone and (+)-Taiwaniaquinone H by Shockley, Samantha E., Holder, Jeffrey C., Stoltz, Brian M.

“…A catalytic, enantioselective formal synthesis of (+)-dichroanone and (+)-taiwaniaquinone H is reported. The all-carbon quaternary stereocenter was constructed…”
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Iridium-Catalyzed Diastereo‑, Enantio‑, and Regioselective Allylic Alkylation with Prochiral Enolates by Hethcox, J. Caleb, Shockley, Samantha E, Stoltz, Brian M

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Enantioselective Synthesis of Acyclic α‐Quaternary Carboxylic Acid Derivatives through Iridium‐Catalyzed Allylic Alkylation by Shockley, Samantha E., Hethcox, J. Caleb, Stoltz, Brian M.

“…The first highly enantioselective iridium‐catalyzed allylic alkylation that provides access to products bearing an allylic all‐carbon quaternary stereogenic…”
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Enantioselective Synthesis of Vicinal All‐Carbon Quaternary Centers via Iridium‐Catalyzed Allylic Alkylation by Hethcox, J. Caleb, Shockley, Samantha E., Stoltz, Brian M.

“…The development of the first enantioselective transition‐metal‐catalyzed allylic alkylation providing access to acyclic products bearing vicinal all‐carbon…”
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Iridium-Catalyzed Stereoselective Allylic Alkylation Reactions with Crotyl Chloride by Hethcox, J. Caleb, Shockley, Samantha E., Stoltz, Brian M.

“…The development of the first enantio‐, diastereo‐, and regioselective iridium‐catalyzed allylic alkylation reaction of prochiral enolates to form an all‐carbon…”
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Palladium-Catalyzed Asymmetric Conjugate Addition of Arylboronic Acids to α,β-Unsaturated Cyclic Electrophiles by Shockley, Samantha E, Holder, Jeffrey C, Stoltz, Brian M

“…This account describes our laboratory’s efforts in the development of a palladium-catalyzed asymmetric conjugate addition of arylboronic acids to cyclic…”
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Building a Culture of Medicinal Chemistry Knowledge Sharing by Beshore, Douglas C, Haidle, Andrew M, Arasappan, Ashok, Lim, Yeon-Hee, Raheem, Izzat, Roecker, Anthony J, Shockley, Samantha E, Simov, Vladimir

“…Increasing the efficiency of the drug discovery process is a challenge faced by drug hunters everywhere. One strategy medicinal chemists employ to meet this…”
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Asymmetric synthesis of all-carbon quaternary spirocycles via a catalytic enantioselective allylic alkylation strategy by Shockley, Samantha E., Hethcox, J. Caleb, Stoltz, Brian M.

“…[Display omitted] •Rapid access to enantioenriched spirocycles possessing a 1,4-dicarbonyl moiety spanning an all-carbon quaternary stereogenic spirocenter was…”
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Iridium-Catalyzed Stereoselective Allylic Alkylation Reactions with Crotyl Chloride by Hethcox, J. Caleb, Shockley, Samantha E., Stoltz, Brian M.

“…The development of the first enantio‐, diastereo‐, and regioselective iridium‐catalyzed allylic alkylation reaction of prochiral enolates to form an all‐carbon…”
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Enantioselective Synthesis of Acyclic α-Quaternary Carboxylic Acid Derivatives via Iridium-Catalyzed Allylic Alkylation by Shockley, Samantha E., Hethcox, J. Caleb, Stoltz, Brian M.

“…The first highly enantioselective iridium-catalyzed allylic alkylation providing access to products bearing an allylic all-carbon quaternary stereogenic center…”
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Enantioselective Synthesis of Acyclic [alpha]-Quaternary Carboxylic Acid Derivatives through Iridium-Catalyzed Allylic Alkylation by Shockley, Samantha E, Hethcox, J Caleb, Stoltz, Brian M

“…The first highly enantioselective iridium-catalyzed allylic alkylation that provides access to products bearing an allylic all-carbon quaternary stereogenic…”
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Enantioselective Synthesis of Acyclic [alpha]-Quaternary Carboxylic Acid Derivatives through Iridium-Catalyzed Allylic Alkylation by Shockley, Samantha E, Hethcox, J Caleb, Stoltz, Brian M

“…The first highly enantioselective iridium-catalyzed allylic alkylation that provides access to products bearing an allylic all-carbon quaternary stereogenic…”
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Enantioselective Synthesis of Acyclic α‐Quaternary Carboxylic Acid Derivatives through Iridium‐Catalyzed Allylic Alkylation by Shockley, Samantha E., Hethcox, J. Caleb, Stoltz, Brian M.

“…The first highly enantioselective iridium‐catalyzed allylic alkylation that provides access to products bearing an allylic all‐carbon quaternary stereogenic…”
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