Search Results - "Shockley, Erin M."

Competition and allostery govern substrate selectivity of cyclooxygenase-2 by Mitchener, Michelle M., Hermanson, Daniel J., Shockley, Erin M., Brown, H. Alex, Lindsley, Craig W., Reese, Jeff, Rouzer, Carol A., Lopez, Carlos F., Marnett, Lawrence J.

“…Cyclooxygenase-2 (COX-2) oxygenates arachidonic acid (AA) and its ester analog, 2-arachidonoylglycerol (2-AG), to prostaglandins (PGs) and prostaglandin…”
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PyDREAM: high-dimensional parameter inference for biological models in python by Shockley, Erin M, Vrugt, Jasper A, Lopez, Carlos F

“…Abstract Summary Biological models contain many parameters whose values are difficult to measure directly via experimentation and therefore require calibration…”
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Signal integration and information transfer in an allosterically regulated network by Shockley, Erin M., Rouzer, Carol A., Marnett, Lawrence J., Deeds, Eric J., Lopez, Carlos F.

“…A biological reaction network may serve multiple purposes, processing more than one input and impacting downstream processes via more than one output. These…”
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Abstract 3763: How stochastic single-cell fate decisions drive population dynamics in oncogene-addicted cancer by Shockley, Erin M., Harris, Leonard A., Lopez, Carlos F.

“…Cancer cells within a tumor environment exhibit a complex and adaptive nature whereby genetically and epigenetically distinct subpopulations compete for…”
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