Search Results - "Shobha, H."

Niacin inhibits fat accumulation, oxidative stress, and inflammatory cytokine IL-8 in cultured hepatocytes: Impact on non-alcoholic fatty liver disease by Ganji, Shobha H, Kashyap, Moti L, Kamanna, Vaijinath S

“…Abstract Objective Non-alcoholic fatty liver disease (NAFLD) is a common disorder characterized by excessive hepatic fat accumulation, production of reactive…”
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Integrating Public and Population Health Into Medical Education Curricula: Opportunities and Challenges for Reform by Mehta, Shobha H, Shah, Nirav R

“…In a review of U.S. medical education curricular guidance, from premedical studies through to continuing medical education, Maeshiro and colleagues found…”
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Niacin inhibits vascular oxidative stress, redox-sensitive genes, and monocyte adhesion to human aortic endothelial cells by Ganji, Shobha H, Qin, Shucun, Zhang, Linhua, Kamanna, Vaijinath S, Kashyap, Moti L

“…Abstract In pharmacological doses, nicotinic acid (niacin) reduces myocardial infarction, stroke and atherosclerosis. The beneficial effects of niacin on…”
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Therapeutic role of niacin in the prevention and regression of hepatic steatosis in rat model of nonalcoholic fatty liver disease by Ganji, Shobha H, Kukes, Gary D, Lambrecht, Nils, Kashyap, Moti L, Kamanna, Vaijinath S

“…Nonalcoholic fatty liver disease (NAFLD), a leading cause of liver damage, comprises a spectrum of liver abnormalities including the early fat deposition in…”
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Recent advances in niacin and lipid metabolism by Kamanna, Vaijinath S., Ganji, Shobha H., Kashyap, Moti L.

“…This review focuses on the current understanding of the physiological mechanisms of action of niacin on lipid metabolism and atherosclerosis. Emerging findings…”
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Shoulder dystocia: Risk factors, predictability, and preventability by Mehta, Shobha H., MD, Sokol, Robert J., MD

“…Abstract Shoulder dystocia remains an unpredictable obstetric emergency, striking fear in the hearts of obstetricians both novice and experienced. While…”
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The Association between Maternal Obesity and Neurodevelopmental Outcomes of Offspring by Mehta, Shobha H., MD, Kerver, Jean M., PhD, MSc, RD, Sokol, Robert J., MD, Keating, Daniel P., PhD, Paneth, Nigel, MD, MPH

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Niacin increases HDL biogenesis by enhancing DR4-dependent transcription of ABCA1 and lipidation of apolipoprotein A-I in HepG2 cells by Zhang, Lin-Hua, Kamanna, Vaijinath S., Ganji, Shobha H., Xiong, Xi-Ming, Kashyap, Moti L.

“…The lipidation of apoA-I in liver greatly influences HDL biogenesis and plasma HDL levels by stabilizing the secreted apoA-I. Niacin is the most effective…”
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Being too large for gestational age precedes childhood obesity in African Americans by Mehta, Shobha H., MD, Kruger, Michael, MS, Sokol, Robert J., MD

“…Objective The purpose of this study was to investigate the association between large-for-gestational-age (LGA) infants and the development of childhood obesity…”
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Niacin decreases leukocyte myeloperoxidase: Mechanistic role of redox agents and Src/p38MAP kinase by Ganji, Shobha H, Kamanna, Vaijinath S, Kashyap, Moti L

“…Abstract Objectives Leukocyte myeloperoxidase (MPO) is a major player in the pathogenesis of various chronic diseases including atherosclerosis. This study…”
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The levels of leptin, adiponectin, and resistin in normal weight, overweight, and obese pregnant women with and without preeclampsia by Hendler, Israel, Blackwell, Sean C., Mehta, Shobha H., Whitty, Janice E., Russell, Evelyne, Sorokin, Yoram, Cotton, David B.

“…The purpose of this study was to compare adipokines' levels between women with and without preeclampsia based on maternal body mass index (BMI). This was a…”
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Iron sucrose promotes endothelial injury and dysfunction and monocyte adhesion/infiltration by Kamanna, Vaijinath S, Ganji, Shobha H, Shelkovnikov, Stanislav, Norris, Keith, Vaziri, Nosratola D

“…Intravenous (IV) iron preparations are widely used in the management of anemia in ESRD populations. Recent changes in reimbursement policy have dramatically…”
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Nutrition and Pregnancy by MEHTA, SHOBHA H

“…The importance of nutrition during pregnancy with regard to pregnancy outcome has long been acknowledged. This importance has only been further emphasized by…”
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Large for gestational age and long-term cognitive function by Paulson, James F., PhD, Mehta, Shobha H., MD, Sokol, Robert J., MD, Chauhan, Suneet P., MD

“…Objective As we have previously published, small-for-gestational-age (<3% birthweight [BW]) newborns exhibit catch-up cognitive functioning by age 2 years. Our…”
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Niacin and cholesterol: role in cardiovascular disease (review) by Ganji, Shobha H., Kamanna, Vaijinath S., Kashyap, Moti L.

“…Niacin has been widely used as a pharmacologic agent to regulate abnormalities in plasma lipid and lipoprotein metabolism and in the treatment of…”
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Institute of Medicine Guidelines for Appropiate Pregnancy Weight Gain for Obese Women May Be Too High by Mehta, Shobha H, Kruger, Michael, Sokol, Robert J

“…To investigate how the 2009 Institute of Medicine (IOM) guidelines for pregnancy weight gain for obese women relate to the longer-term outcome of childhood…”
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Niacin noncompetitively inhibits DGAT2 but not DGAT1 activity in HepG2 cells by Ganji, S.H, Tavintharan, S, Zhu, D, Xing, Y, Kamanna, V.S, Kashyap, M.L

“…Niacin is a widely used lipid-regulating agent in dyslipidemic patients. Previously, we have shown that niacin inhibits triacylglycerol synthesis. In this…”
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Pioglitazone increases apolipoprotein A-I production by directly enhancing PPRE-dependent transcription in HepG2 cells by Zhang, Lin-Hua, Kamanna, Vaijinath S., Ganji, Shobha H., Xiong, Xi-Ming, Kashyap, Moti L.

“…Pioglitazone, a hypoglycemic agent, has been shown to increase plasma HDL cholesterol, but the mechanism is incompletely understood. We further investigated…”
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Peripheral venous access in the obese patient by Prakash, Smita, Arora, Gaurav, Rani, Hg Shobha

“…The operation table was tilted [approximate]20 head-down (to make neck veins prominent), and the right external jugular vein was cannulated. Predictive factors…”
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Is maternal diabetes a risk factor for childhood obesity? by Mehta, Shobha H., Kruger, Michael, Sokol, Robert J.

“…Objective: Our objective is to determine if there is a relationship between diabetes during pregnancy and childhood obesity, in our inner-city,…”
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