Search Results - "Shmendel, E. V."

Influence of Liposome Composition on Plasmid DNA Delivery to Eukaryotic Cells by Mikheev, A. A., Shmendel, E. V., Nazarov, G. V., Maslov, M. A.

“…Gene therapy is a promising method for the treatment of various diseases by introducing therapeutic nucleic acids, for the delivery of which cationic liposomes…”
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Non-Phosphorus Lipids As New Antitumor Drug Prototypes by Varlamova, E. A., Isagulieva, A. K., Morozova, N. G., Shmendel, E. V., Maslov, M. A., Shtil, A. A.

“…The main classes of antitumor drugs (antimetabolites, anthracyclines, taxanes, and alkylating agents) act via DNA damage, inhibit DNA synthesis, and/or…”
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Targeted Delivery of Nucleic Acids by Folate-Containing Liposomes into KB-3-1 and HEK 293 Cells by Shmendel, E. V., Kabilova, T. O., Morozova, N. G., Zenkova, M. A., Maslov, M. A.

“…Targeted cationic liposomes containing folate lipoconjugates with spacer groups of various lengths and natures were prepared; their physicochemical…”
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Optimization of the Technology for the Preparation of Cationic Liposomes for the Delivery of Nucleic Acids by Luneva, A. S., Puchkov, P. A., Shmendel, E. V., Zenkova, M. A., Kuzevanova, A. Yu, Alimov, A. A., Karpukhin, A. V., Maslov, M. A.

“…Cationic liposomes based on the cationic lipid 1,26-bis(cholest-5-en-3β-yloxycarbonylamino)- 7,11,16-2-tetraazahexacosane tetrahydrochloride (2X3) and the…”
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Сationic liposomes as delivery systems for nucleic acids by Mikheev, A. A., Shmendel, E. V., Zhestovskaya, E. S., Nazarov, G. V., Maslov, M. A.

“…Objectives . Gene therapy is based on the introduction of genetic material into cells, tissues, or organs for the treatment of hereditary or acquired diseases…”
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Systemic delivery of complexes of melanoma RNA with mannosylated liposomes activates highly efficient murine melanoma-specific cytotoxic T cells in vivo by Markov, O. V., Mironova, N. L., Shmendel, E. V., Maslov, M. A., Zenkova, M. A.

“…The efficiency of the antitumor immune response triggered by dendritic cell (DC)-based vaccines depends predominantly on the efficiency of delivering tumor…”
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Synthesis of neoglycolipids for the development of non-viral gene delivery systems by Shmendel’, E. V., Maslov, M. A., Morozova, N. G., Serebrennikova, G. A.

“…Synthesis of lipid conjugates with galactose as a targeting ligand intended for the development of non-viral systems for the targeted delivery of nucleic acids…”
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Synthesis of mannose-containing neoglycolipids as a component of targeted delivery system for transfer of nucleic acids into antigen-presenting cells by Shmendel’, E. V., Timakova, A. A., Maslov, M. A., Morozova, N. G., Chupin, V. V.

“…Two approaches to the preparation of mannose-containing neoglycolipid, designed for development of nonviral targeted delivery system for transfer of nucleic…”
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Uncharged Gemini-Amphiphiles as Components of Cationic Liposomes for Delivery of Nucleic Acids by Shmendel, E. V., Bakhareva, S. A., Makarova, D. M., Chernikov, I. V., Morozova, N. G., Chernolovskaya, E. L., Zenkova, M. A., Maslov, M. A.

“…New uncharged gemini-amphiphiles have been synthesized. A series of cationic liposomes based on the polycationic amphiphile…”
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Synthesis of new carbohydrate-containing cationic alkyl glycerolipids with antitumor activity by Shmendel, E. V., Perevoshchikova, K. A., Shishova, D. K., Kubasova, T. S., Tyutyunnik, L. L., Maslov, M. A., Morozova, N. G., Shtil, A. A.

“…New non-phosphorous carbohydrate-containing cationic alkyl glycerolipids bearing a ter- minal glycosyl moiety were synthesized. An approach used for the…”
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Synthesis of folate lipoconjugates with hydrophobic spacers by E. V. Shmendel, S. V. Eremin, N. G. Morozova, M. A. Maslov

“…Folate lipoconjugates were synthesized by induction of spacers to 1,2-di-O-tetradecyl-rac-glycerol for future condensation with folic acid. The intermediates…”
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Time course of fluorescent-labelled oligonucleotide accumulation in cells with the use of folate receptor-targeted cationic liposomes by Shmendel, E. V., Markov, O. V., Zenkova, M. A., Maslov, M. A.

“…INTRODUCTION . The use of cationic liposomes is a promising approach to the delivery of therapeutic nucleic acids to target cells because liposomes can protect…”
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