Search Results - "Shkolnikov, Nicholas"

CRISPR/Cas9 Genome Editing of the Human Topoisomerase IIα Intron‐19 5′ Splice Site Circumvents Etoposide Resistance in Human Leukemia K562 Cells by Hernandez, Victor, Carvajal‐Moreno, Jessika, Papa, Jonathan, Shkolnikov, Nicholas, Li, Junan, Ozer, Hatice, Yalowich, Jack, Elton, Terry

“…An essential function of DNA topoisomerase IIα (170 kDa, TOP2α/170) is to resolve DNA topologic entanglements during chromosome dysjunction by introducing…”
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CRISPR/Cas9 Genome Editing of the Human Topoisomerase II α Intron 19 5' Splice Site Circumvents Etoposide Resistance in Human Leukemia K562 Cells by Hernandez, Victor A, Carvajal-Moreno, Jessika, Papa, Jonathan L, Shkolnikov, Nicholas, Li, Junan, Ozer, Hatice Gulcin, Yalowich, Jack C, Elton, Terry S

“…An essential function of DNA topoisomerase II (TOP2 ; 170 kDa, TOP2 /170) is to resolve DNA topologic entanglements during chromosome disjunction by…”
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hsa-miR-9-3p and hsa-miR-9-5p as Post-Transcriptional Modulators of DNA Topoisomerase II α in Human Leukemia K562 Cells with Acquired Resistance to Etoposide by Kania, Evan E, Carvajal-Moreno, Jessika, Hernandez, Victor A, English, Anthony, Papa, Jonathan L, Shkolnikov, Nicholas, Ozer, Hatice Gulcin, Yilmaz, Ayse Selen, Yalowich, Jack C, Elton, Terry S

“…DNA topoisomerase II protein (TOP2 ) 170 kDa (TOP2 /170) is an important target for anticancer agents whose efficacy is often attenuated by chemoresistance…”
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Dioxane-Linked Amide Derivatives as Novel Bacterial Topoisomerase Inhibitors against Gram-Positive Staphylococcus aureus by Lu, Yanran, Papa, Jonathan L, Nolan, Sheri, English, Anthony, Seffernick, Justin T, Shkolnikov, Nicholas, Powell, Josh, Lindert, Steffen, Wozniak, Daniel J, Yalowich, Jack, Mitton-Fry, Mark J

“…In recent years, novel bacterial topoisomerase inhibitors (NBTIs) have been developed as future antibacterials for treating multidrug-resistant bacterial…”
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