Search Results - "Shivajirao, S S"
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Anticancer and antimetastatic potential of enterolactone: Clinical, preclinical and mechanistic perspectives
Published in European journal of pharmacology (05-06-2019)“…Currently cancer is the second leading cause of death globally and worldwide incidence and mortality rates of all cancers of males and females are rising…”
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Enterolactone modulates the ERK/NF-κB/Snail signaling pathway in triple-negative breast cancer cell line MDA-MB-231 to revert the TGF-β-induced epithelial-mesenchymal transition
Published in Cancer biology & medicine (01-05-2018)“…Triple-negative breast cancer (TNBC) is highly metastatic, and there is an urgent unmet need to develop novel therapeutic strategies leading to the new drug…”
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FAT1 on YAP1-TEAD1 interaction augments oncogenic potential of GBM cells
Published in Annals of oncology (01-10-2018)Get full text
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Pharmacophore generation and atom-based 3D-QSAR of novel 2-(4-methylsulfonylphenyl)pyrimidines as COX-2 inhibitors
Published in Molecular diversity (01-08-2010)“…Cyclooxygenase-2 (COX-2) inhibitors are widely used for the treatment of pain and inflammatory disorders such as rheumatoid arthritis and osteoarthritis. A…”
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Pluronic gels for nasal delivery of Vitamin B12. Part I: Preformulation study
Published in International journal of pharmaceutics (11-02-2004)“…Thermoreversible nasal gels of Vitamin B(12) using pluronic PF 127 were aimed to improve absorption and patient compliance. In the present research work,…”
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Effect of Drying Methods on Swelling, Erosion and Drug Release from Chitosan–Naproxen Sodium Complexes
Published in AAPS PharmSciTech (01-03-2008)“…The purpose of this research was to explore theapplication of ionic interactions between naproxen sodium (NS) and chitosan (CH) in complexes (NSC) prepared by…”
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Reduced Ulcerogenic Potential and Antiarthritic Effect of Chitosan–Naproxen Sodium Complexes
Published in AAPS PharmSciTech (01-09-2012)“…The purpose of this research was to address the utility of naproxen sodium–chitosan spray-dried complexes for antiulcer and antiarthritic activities. The cold…”
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Effect of oppositely charged polymer and dissolution medium on swelling, erosion, and drug release from chitosan matrices
Published in AAPS PharmSciTech (01-06-2007)“…The purpose of this research was to investigate the potential use of anionick-carrageenan and nonionic hydroxypropyl-methylcellulose (HPMC, K4) to improve the…”
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Human protein tyrosine phosphatase 1B inhibitors: QSAR by genetic function approximation
Published in Journal of enzyme inhibition and medicinal chemistry (01-06-2007)“…Protein tyrosine phosphatase 1B (PTP 1B), a negative regulator of insulin receptor signaling system, has emerged as a highly validated, attractive target for…”
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Crystallo-co-agglomeration: a novel technique to obtain ibuprofen-paracetamol agglomerates
Published in AAPS PharmSciTech (01-01-2004)“…The purpose of this research was to obtain directly compressible agglomerates of ibuprofen-paracetamol containing a desired ratio of drugs using a…”
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Effect of Oppositely Charged Polymer and Dissolution Media on Rheology of Spray-Dried Ionic Complexes
Published in AAPS PharmSciTech (01-03-2010)“…The purpose of this research was to address the utility of rheological study in understanding the influence of oppositely charged polymers on release of…”
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Development and Validation of a TLC-Densitometric Method for the Simultaneous Quantitation of Strychnine and Brucine from Strychnos spp. and its Formulations
Published in Journal of chromatographic science (01-11-2007)“…A simple, sensitive, and specific thin-layer chromatography densitometric method has been developed for the simultaneous quantitation of strychnine and…”
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Chromatographic determination of itopride hydrochloride in the presence of its degradation products
Published in Journal of separation science (01-08-2005)“…Two sensitive and reproducible methods are described for the quantitative determination of itopride hydrochloride (IH) in the presence of its degradation…”
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3D-QSAR of histone deacetylase inhibitors as anticancer agents by genetic function approximation
Published in Indian journal of biochemistry & biophysics (01-12-2006)“…Histone deacetylases (HDACs) play a critical role in gene transcription and are implicated in cancer therapy and other diseases. Inhibitors of HDACs induce…”
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Recent advances in inhalable liposomes for treatment of pulmonary diseases: Concept to clinical stance
Published in Journal of drug delivery science and technology (01-04-2020)“…Liposomes and liposomes-based drug delivery systems are promising carriers in the rapidly evolving field of nanomedicine. Liposomes are receiving growing…”
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Influence of modified induction port, modified DUSA assembly and device air-inlet geometry on the aerosolization pattern of a dry powder inhaler
Published in Journal of drug delivery science and technology (01-02-2020)“…The objective of the present investigation was to study the effect of inhaler air-inlet size, induction port (IP) geometry and modified dose unit sampling…”
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Exploring the impact of extrinsic lactose fines, a USP modified sampling device and modified centrifuge tube on the delivered dose uniformity and drug detachment performance of a fluticasone propionate dry powder inhaler
Published in Journal of drug delivery science and technology (01-06-2020)“…The present study aimed to probe influences exerted by extrinsic lactose fines on drug detachment and delivered dose uniformity (DDU) of fluticasone propionate…”
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Effect of USP induction ports and modified glass sampling apparatus on aerosolization performance of lactose carrier-based fluticasone propionate dry powder inhaler
Published in Journal of drug delivery science and technology (01-08-2020)“…In the present study, a lactose based dry powder inhaler (DPI) was formulated to probe the effect of three different US Pharmacopeia (USP) induction port (IP)…”
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393PFAT1 on YAP1-TEAD1 interaction augments oncogenic potential of GBM cells
Published in Annals of oncology (01-10-2018)Get full text
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