Search Results - "Shiuh-Wen Luoh"

Prognostic and therapeutic role of tumor-infiltrating lymphocyte subtypes in breast cancer by Nelson, Molly A., Ngamcherdtrakul, Worapol, Luoh, Shiuh-Wen, Yantasee, Wassana

“…Increased levels of total tumor-infiltrating lymphocytes (TILs) are generally associated with good prognosis in several breast cancer subtypes. Subtypes of…”
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In Situ Tumor Vaccination with Nanoparticle Co‐Delivering CpG and STAT3 siRNA to Effectively Induce Whole‐Body Antitumor Immune Response by Ngamcherdtrakul, Worapol, Reda, Moataz, Nelson, Molly A., Wang, Ruijie, Zaidan, Husam Y., Bejan, Daniel S., Hoang, Ngoc Ha, Lane, Ryan S., Luoh, Shiuh‐Wen, Leachman, Sancy A., Mills, Gordon B., Gray, Joe W., Lund, Amanda W., Yantasee, Wassana

“…The success of immunotherapy with immune checkpoint inhibitors (ICIs) in a subset of individuals has been very exciting. However, in many cancers, responses to…”
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Mutation of SIVA, a candidate metastasis gene identified from clonally related bilateral breast cancers, promotes breast cancer cell spread in vitro and in vivo by Vermehren-Schmaedick, Anke, Peto, Myron, Wagoner, Wendy, Chiotti, Kami E, Ramsey, Elizabeth, Wang, Xiaoyan, Rakshe, Shauna, Minnier, Jessica, Sears, Rosalie, Spellman, Paul, Luoh, Shiuh-Wen

“…Metastasis is the most dreaded outcome after a breast cancer diagnosis, and little is known regarding what triggers or promotes breast cancer to spread…”
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GRB7 dependent proliferation of basal‐like, HER‐2 positive human breast cancer cell lines is mediated in part by HER‐1 signaling by Luoh, Shiuh‐Wen, Wagoner, Wendy, Wang, Xiaoyan, Hu, Zhi, Lai, Xinhe, Chin, Koei, Sears, Rosalie, Ramsey, Elizabeth

“…GRB7 gene encodes a multi‐domain signal transduction molecule and is part of the core of the HER‐2 amplicon. GRB7 is commonly co‐amplified and overexpressed…”
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Grb7 Ablation in Mice Improved Glycemic Control, Enhanced Insulin Signaling, and Increased Abdominal fat Mass in Females by Vermehren-Schmaedick, Anke, Joshi, Sonali, Wagoner, Wendy, Norgard, Mason A, Packwood, William, Diba, Parham, Mendez, Heike, Fedorov, Lev M, Rakshe, Shauna, Park, Byung, Marks, Daniel L, Grossberg, Aaron, Luoh, Shiuh-Wen

“…Abstract Objectives Growth factor receptor bound protein 7 (GRB7) is a multidomain signaling adaptor. Members of the Grb7/10/14 family, specifically Gbrb10/14,…”
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A Phenome-Wide Association Study of genes associated with COVID-19 severity reveals shared genetics with complex diseases in the Million Veteran Program by Verma, Anurag, Tsao, Noah L, Thomann, Lauren O, Ho, Yuk-Lam, Iyengar, Sudha K, Luoh, Shiuh-Wen, Carr, Rotonya, Crawford, Dana C, Efird, Jimmy T, Huffman, Jennifer E, Hung, Adriana, Ivey, Kerry L, Levin, Michael G, Lynch, Julie, Natarajan, Pradeep, Pyarajan, Saiju, Bick, Alexander G, Costa, Lauren, Genovese, Giulio, Hauger, Richard, Madduri, Ravi, Pathak, Gita A, Polimanti, Renato, Voight, Benjamin, Vujkovic, Marijana, Zekavat, Seyedeh Maryam, Zhao, Hongyu, Ritchie, Marylyn D, Chang, Kyong-Mi, Cho, Kelly, Casas, Juan P, Tsao, Philip S, Gaziano, J Michael, O'Donnell, Christopher, Damrauer, Scott M, Liao, Katherine P

“…The study aims to determine the shared genetic architecture between COVID-19 severity with existing medical conditions using electronic health record (EHR)…”
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Pharmacogenetic variants and risk of remdesivir‐associated liver enzyme elevations in Million Veteran Program participants hospitalized with COVID‐19 by Tuteja, Sony, Yu, Zhihong, Wilson, Otis, Chen, Hua‐Chang, Wendt, Frank, Chung, Cecilia P., Shah, Shailja C., Hunt, Christine M., Suzuki, Ayako, Chanfreau, Catherine, Gorman, Bryan R., Joseph, Jacob, Luoh, Shiuh‐Wen, Napolioni, Valerio, Robinson‐Cohen, Cassianne, Tao, Ran, Zhou, Jin, Chang, Kyong‐Mi, Hung, Adriana M.

“…Remdesivir is the first US Food and Drug Administration (FDA)‐approved drug for the treatment of coronavirus disease 2019 (COVID‐19). We conducted a…”
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Identifying Factors Associated With Falls in Postmenopausal Breast Cancer Survivors: A Multi-Disciplinary Approach by Winters-Stone, Kerri M., PhD, Torgrimson, Britta, PhD, Horak, Fay, PhD, PT, Eisner, Alvin, PhD, Nail, Lillian, PhD, RN, Leo, Michael C., PhD, Chui, Steve, MD, Luoh, Shiuh-Wen, MD

“…Abstract Winters-Stone KM, Torgrimson B, Horak F, Eisner A, Nail L, Leo MC, Chui S, Luoh S-W. Identifying factors associated with falls in postmenopausal…”
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GRB-7 facilitates HER-2/Neu-mediated signal transduction and tumor formation by Bai, Tao, Luoh, Shiuh-Wen

“…Growth factor receptor-bound protein-7 (GRB-7), an adaptor molecule, can interact with multiple signal transduction molecules. GRB-7 is amplified concurrently…”
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Comparison of Mortality Among Participants of Women’s Health Initiative Trials With Screening-Detected Breast Cancers vs Interval Breast Cancers by Irvin, Veronica L., Zhang, Zhenzhen, Simon, Michael S., Chlebowski, Rowan T., Luoh, Shiuh-Wen, Shadyab, Aladdin H., Krok-Schoen, Jessica L., Tabung, Fred K., Qi, Lihong, Stefanick, Marcia L., Schedin, Pepper, Jindal, Sonali

“…Importance Interval breast cancers (IBCs) are cancers that emerge after a mammogram with negative results but before the patient’s next scheduled screening…”
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Quantitative progesterone receptor expression and efficacy of anti-estrogen therapy in breast cancer by Luoh, Shiuh-Wen, Ramsey, Betsy, Park, Byung, Keenan, Edward

“…The central role of estrogen receptor (ER) presence in predicting which breast cancer patients are likely to benefit from anti-estrogen therapies is…”
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Comparison of tai chi vs. strength training for fall prevention among female cancer survivors: study protocol for the GET FIT trial by Winters-Stone, Kerri M, Li, Fuzhong, Horak, Fay, Luoh, Shiuh-Wen, Bennett, Jill A, Nail, Lillian, Dieckmann, Nathan

“…Women with cancer are significantly more likely to fall than women without cancer placing them at higher risk of fall-related fractures, other injuries and…”
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A translational genomics approach identifies IL10RB as the top candidate gene target for COVID-19 susceptibility by Voloudakis, Georgios, Vicari, James M., Venkatesh, Sanan, Hoffman, Gabriel E., Dobrindt, Kristina, Zhang, Wen, Beckmann, Noam D., Higgins, Christina A., Argyriou, Stathis, Jiang, Shan, Hoagland, Daisy, Gao, Lina, Corvelo, André, Cho, Kelly, Lee, Kyung Min, Bian, Jiantao, Lee, Jennifer S., Iyengar, Sudha K., Luoh, Shiuh-Wen, Akbarian, Schahram, Striker, Robert, Assimes, Themistocles L., Schadt, Eric E., Lynch, Julie A., Merad, Miriam, tenOever, Benjamin R., Charney, Alexander W., Brennand, Kristen J., Fullard, John F., Roussos, Panos

“…Recent efforts have identified genetic loci that are associated with coronavirus disease 2019 (COVID-19) infection rates and disease outcome severity…”
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When Tissue Is No Longer the Issue: Tissue-Agnostic Cancer Therapy Comes of Age by Luoh, Shiuh-Wen, Flaherty, Keith T

“…Matching unique features of cancer types with effective therapies is a cornerstone of precision medicine. Clinical success has been seen in inhibiting specific…”
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Cyclic Multiplexed-Immunofluorescence (cmIF), a Highly Multiplexed Method for Single-Cell Analysis by Eng, Jennifer, Thibault, Guillaume, Luoh, Shiuh-Wen, Gray, Joe W, Chang, Young Hwan, Chin, Koei

“…Immunotherapy harnesses the power of the adaptive immune system and has revolutionized the field of oncotherapy, as novel therapeutic strategies have been…”
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GET FIT: A Randomized Clinical Trial of Tai Ji Quan Versus Strength Training for Fall Prevention After Chemotherapy in Older, Postmenopausal Women Cancer Survivors by Winters-Stone, Kerri M, Horak, Fay, Dieckmann, Nathan F, Luoh, Shiuh-Wen, Eckstrom, Elizabeth, Stoyles, Sydnee A, Roeland, Eric J, Li, Fuzhong

“…To compare the efficacy of tai ji quan versus strength training to prevent falls after chemotherapy in older, postmenopaual women. We conducted a three-arm,…”
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Reply to: Sookaromdee and Wiwanitkit by Wan, Emily S, Verma, Anurag, Minnier, Jessica, Luoh, Shiuh-Wen, Iyengar, Sudha K

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Overexpression of the amplified Pip4k2β gene from 17q11-12 in breast cancer cells confers proliferation advantage by LUOH, Shiuh-Wen, VENKATESAN, Natarajan, TRIPATHI, Reshimi

“…Gene amplification is common in solid tumors and is associated with adverse prognosis, disease progression, and development of drug resistance. A small segment…”
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Reply to Y.-T. Hu et al by Winters-Stone, Kerri M, Roeland, Eric J, Li, Fuzhong, Eckstrom, Elizabeth, Horak, Fay, Dieckmann, Nathan F, Stoyles, Sydnee A, Luoh, Shiuh-Wen

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Breast Cancer Medications and Vision: Effects of Treatments for Early-stage Disease by Eisner, Alvin, Luoh, Shiuh-Wen

“…This review concerns the effects on vision and the eye of medications prescribed at three phases of treatment for women with early-stage breast cancer (BC):…”
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