Search Results - "Shirsat, Neelam Vishwanath"

ETV/Pea3 family transcription factor-encoding genes are overexpressed in CIC-mutant oligodendrogliomas by Padul, Vijay, Epari, Sridhar, Moiyadi, Aliasgar, Shetty, Prakash, Shirsat, Neelam Vishwanath

“…Oligodendrogliomas with combined loss of chromosome arms 1p and 19q are known to be particularly sensitive to chemotherapy, and the CIC gene located on 19q is…”
Get full text

MiR-224 expression increases radiation sensitivity of glioblastoma cells by Upraity, Shailendra, Kazi, Sadaf, Padul, Vijay, Shirsat, Neelam Vishwanath

“…•MiR-224 expression in established glioblastoma cell lines and sporadic tumor tissues is low.•Exogenous miR-224 expression was found to increase radiation…”
Get full text

Restoration of miR-193a expression is tumor-suppressive in MYC amplified Group 3 medulloblastoma by Bharambe, Harish Shrikrishna, Joshi, Annada, Yogi, Kedar, Kazi, Sadaf, Shirsat, Neelam Vishwanath

“…Medulloblastoma, a highly malignant pediatric brain tumor, consists of four molecular subgroups, namely WNT, SHH, Group 3, and Group 4. The expression of…”
Get full text

Downregulation of miR-204 expression defines a highly aggressive subset of Group 3/Group 4 medulloblastomas by Bharambe, Harish Shrikrishna, Paul, Raikamal, Panwalkar, Pooja, Jalali, Rakesh, Sridhar, Epari, Gupta, Tejpal, Moiyadi, Aliasgar, Shetty, Prakash, Kazi, Sadaf, Deogharkar, Akash, Masurkar, Shalaka, Yogi, Kedar, Kunder, Ratika, Gadewal, Nikhil, Goel, Atul, Goel, Naina, Chinnaswamy, Girish, Ramaswamy, Vijay, Shirsat, Neelam Vishwanath

“…Genome-wide expression profiling studies have identified four core molecular subgroups of medulloblastoma: WNT, SHH, Group 3 and Group 4. Molecular markers are…”
Get full text

Real-Time PCR Assays on Formalin-Fixed, Paraffin-Embedded Medulloblastomas by Kunder, Ratika, Shirsat, Neelam Vishwanath

“…Real-time PCR technology has been instrumental in contributing toward biomarker discovery, classification of tumors as well as risk stratification of patients…”
Get more information

Downregulation of CRX, a Group 3-specific oncogenic transcription factor, inhibits TGF-β/activin signaling in medulloblastoma cells by Masurkar, Shalaka Arun, Deogharkar, Akash, Bharambe, Harish Shrikrishna, Shirsat, Neelam Vishwanath

“…Medulloblastoma, the most common malignant brain tumor in children, consists of four molecular subgroups WNT, SHH, Group 3, and Group 4. Group 3 has the worst…”
Get full text

MiR-592 activates the mTOR kinase, ERK1/ERK2 kinase signaling and imparts neuronal differentiation signature characteristic of Group 4 medulloblastoma by Paul, Raikamal, Bapat, Purna, Deogharkar, Akash, Kazi, Sadaf, Singh, Satish Kumar Vishram, Gupta, Tejpal, Jalali, Rakesh, Sridhar, Epari, Moiyadi, Aliasgar, Shetty, Prakash, Shirsat, Neelam Vishwanath

Get full text

MiR-592 activates the mTOR kinase, ERK1/ERK2 kinase signaling and imparts neuronal differentiation signature characteristic of Group 4 medulloblastoma by Paul, Raikamal, Bapat, Purna, Deogharkar, Akash, Kazi, Sadaf, Singh, Satish Kumar Vishram, Gupta, Tejpal, Jalali, Rakesh, Sridhar, Epari, Moiyadi, Aliasgar, Shetty, Prakash, Shirsat, Neelam Vishwanath

“…Abstract Medulloblastoma, a common malignant brain tumor in children, consists of four molecular subgroups WNT, SHH, Group 3 and Group 4. Group 3, Group 4…”
Get full text

Tamoxifen-Induced Cell Death of Malignant Glioma Cells Is Brought About by Oxidative-Stress-Mediated Alterations in the Expression of BCL2 Family Members and Is Enhanced on miR-21 Inhibition by Harmalkar, Mugdha, Upraity, Shailendra, Kazi, Sadaf, Shirsat, Neelam Vishwanath

“…High-grade gliomas are refractory to the current mode of treatment primarily due to their inherent resistance to cell death. Tamoxifen has been reported to…”
Get full text

Restoration of miR-30a expression inhibits growth, tumorigenicity of medulloblastoma cells accompanied by autophagy inhibition by Singh, Satishkumar Vishram, Dakhole, Aditi Nigam, Deogharkar, Akash, Kazi, Sadaf, Kshirsagar, Rohan, Goel, Atul, Moiyadi, Aliasgar, Jalali, Rakesh, Sridhar, Epari, Gupta, Tejpal, Shetty, Prakash, Gadewal, Nikhil, Shirsat, Neelam Vishwanath

“…Medulloblastoma is a highly malignant pediatric brain tumor. About 30% patients have metastasis at diagnosis and respond poorly to treatment. Those that…”
Get full text

Downregulation of ARID1B, a tumor suppressor in the WNT subgroup medulloblastoma, activates multiple oncogenic signaling pathways by Deogharkar, Akash, Singh, Satishkumar Vishram, Bharambe, Harish Shrikrishna, Paul, Raikamal, Moiyadi, Aliasgar, Goel, Atul, Shetty, Prakash, Sridhar, Epari, Gupta, Tejpal, Jalali, Rakesh, Goel, Naina, Gadewal, Nikhil, Muthukumar, Sahana, Shirsat, Neelam Vishwanath

“…Abstract Medulloblastoma, a common pediatric malignant brain tumor, consists of four distinct molecular subgroups WNT, SHH, Group 3 and Group 4. Exome…”
Get full text

Autophagy inhibition impairs the invasion potential of medulloblastoma cells by Paul, Raikamal, Bharambe, Harish, Shirsat, Neelam Vishwanath

“…Medulloblastoma, a highly malignant pediatric brain tumor, consists of four distinct molecular subgroups called WNT, SHH, Group 3, and Group 4 that differ in…”
Get full text

Real-time PCR assay based on the differential expression of microRNAs and protein-coding genes for molecular classification of formalin-fixed paraffin embedded medulloblastomas by Kunder, Ratika, Jalali, Rakesh, Sridhar, Epari, Moiyadi, Aliasgar, Goel, Naina, Goel, Atul, Gupta, Tejpal, Krishnatry, Rahul, Kannan, Sadhana, Kurkure, Purna, Deopujari, Chandrashekhar, Shetty, Prakash, Biyani, Naresh, Korshunov, Andrey, Pfister, Stefan M, Northcott, Paul A, Shirsat, Neelam Vishwanath

“…Medulloblastoma has recently been found to consist of 4 molecularly and clinically distinct subgroups: WNT, Sonce hedgehog (SHH), Group 3, and Group 4…”
Get full text

Distinctive microRNA signature of medulloblastomas associated with the WNT signaling pathway by Gokhale, Amit, Kunder, Ratika, Goel, Atul, Sarin, Rajiv, Moiyadi, Aliasgar, Shenoy, Asha, Mamidipally, Chandrasekhar, Noronha, Santosh, Kannan, Sadhana, Shirsat, Neelam Vishwanath

“…Medulloblastoma is a malignant brain tumor that occurs predominantly in children. Current risk stratification based on clinical parameters is inadequate for…”
Get full text

MiR-148a, a microRNA upregulated in the WNT subgroup tumors, inhibits invasion and tumorigenic potential of medulloblastoma cells by targeting Neuropilin 1 by Yogi, Kedar, Sridhar, Epari, Goel, Naina, Jalali, Rakesh, Goel, Atul, Moiyadi, Aliasgar, Thorat, Rahul, Panwalkar, Pooja, Khire, Atul, Dasgupta, Archya, Shetty, Prakash, Shirsat, Neelam Vishwanath

“…Medulloblastoma, a common pediatric malignant brain tumor consists of four molecular subgroups viz. WNT, SHH, Group 3 and Group 4. MiR-148a is over-expressed…”
Get full text

Distinctive microRNA signature of medulloblastomas associated with the WNT signaling pathway by Gokhale, Amit, Kunder, Ratika, Goel, Atul, Sarin, Rajiv, Moiyadi, Aliasgar, Shenoy, Asha, Mamidipally, Chandrasekhar, Noronha, Santosh, Kannan, Sadhana, Shirsat, Neelam Vishwanath

“…Aim: Medulloblastoma is a malignant brain tumor that occurs predominantly in children. Current risk stratification based on clinical parameters is inadequate…”
Get full text