Search Results - "Shirley, Joshua D."

Rapidly growing knowledge of Mycobacterium smegmatis: A case series and review of antimicrobial susceptibility patterns by Crowley, Patrick D., Vaillant, James J., Shirley, Joshua D., Wengenack, Nancy L., Jo Kasten, Mary

“…Mycobacterium smegmatis is a rapidly growing nontuberculous mycobacterium that is rarely isolated from clinical specimens and is frequently considered to be a…”
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Enzyme-targeted fluorescent small-molecule probes for bacterial imaging by Marshall, Andrew P., Shirley, Joshua D., Carlson, Erin E.

“…Molecular imaging methods to visualize myriad biochemical processes in bacteria have traditionally been dependent upon molecular biology techniques to…”
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Looks can be deceiving: Bacterial enzymes work through unanticipated mechanism by Shirley, Joshua D., Carlson, Erin E.

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Current regulatory landscape for viral point-of-care testing in the United States by Shirley, Joshua D., Bennett, Shannon A., Binnicker, Matthew J.

“…•POC testing provides rapid diagnostics at the point of patient contact.•POC testing includes both serology (antigen and antibody) and molecular…”
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Failure of mecA/mecC PCR Testing to Accurately Predict Oxacillin Resistance in a Patient with Staphylococcus aureus Infective Endocarditis by Hess, Kyle A, Kooda, Kirstin, Shirley, Joshua D, Schuetz, Audrey N, Abu Saleh, Omar, Stevens, Ryan W

“…Genotypic testing for / is heavily relied upon for rapid optimization of antimicrobial therapy in infections due to Staphylococcus aureus. Little is known…”
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The Brief Case: An unexpected cause of meningoencephalitis in an infant by Shirley, Joshua D, Ngo, Tiffany T, Patel, Jenny A, Pritt, Bobbi S, Gaensbauer, James T, Theel, Elitza S

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Comparison of Bioorthogonal β‐Lactone Activity‐Based Probes for Selective Labeling of Penicillin‐Binding Proteins by Brown, Nathaniel W., Shirley, Joshua D., Marshall, Andrew P., Carlson, Erin E.

“…Penicillin‐binding proteins (PBPs) are a family of bacterial enzymes that are key components of cell‐wall biosynthesis and the target of β‐lactam antibiotics…”
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Leptotrichia Bacteremia: 10-Year Retrospective Clinical Analysis and Antimicrobial Susceptibility Profiles by Ranganath, Nischal, Shirley, Joshua D, Challener, Douglas W, Stevens, Ryan W, Kind, Dalton R, Comba, Isin Y, Patel, Robin, Schuetz, Audrey N, Shah, Aditya S

“…species are anaerobic, Gram-negative bacilli increasingly recognized as pathogens capable of causing invasive infections such as bloodstream infection (BSI),…”
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Combined Structural Analysis and Molecular Dynamics Reveal Penicillin-Binding Protein Inhibition Mode with β‑Lactones by Flanders, Parker L., Contreras-Martel, Carlos, Brown, Nathaniel W., Shirley, Joshua D., Martins, Alexandre, Nauta, Kelsie N., Dessen, Andréa, Carlson, Erin E., Ambrose, Elizabeth A.

“…β-Lactam antibiotics comprise one of the most widely used therapeutic classes to combat bacterial infections. This general scaffold has long been known to…”
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Live-Cell Profiling of Penicillin-Binding Protein Inhibitors in Escherichia coli MG1655 by Shirley, Joshua D., Nauta, Kelsie M., Carlson, Erin E.

“…Penicillin-binding proteins (PBPs) make up an essential class of bacterial enzymes that carry out the final steps of peptidoglycan synthesis and regulate the…”
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Novel Electrophilic Scaffold for Imaging of Essential Penicillin-Binding Proteins in Streptococcus pneumoniae by Sharifzadeh, Shabnam, Boersma, Michael J, Kocaoglu, Ozden, Shokri, Alireza, Brown, Clayton L, Shirley, Joshua D, Winkler, Malcolm E, Carlson, Erin E

“…Peptidoglycan (PG) is a mesh-like heteropolymer made up of glycan chains cross-linked by short peptides and is the major scaffold of eubacterial cell walls,…”
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Activity-Based Protein Profiling Methods to Study Bacteria: The Power of Small-Molecule Electrophiles by Sharifzadeh, Shabnam, Shirley, Joshua D, Carlson, Erin E

“…ABPP methods have been utilized for the last two decades as a means to investigate complex proteomes in all three domains of life. Extensive use in eukaryotes…”
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Real-Time Visualization of in Vitro Transcription of a Fluorescent RNA Aptamer: An Experiment for the Upper-Division Undergraduate or First-Year Graduate Laboratory by Heili, Joseph M, Gomez-Garcia, Jose, Gaut, Nathaniel J, Cash, Brock W, Aufdembrink, Lauren M, Heffron, Brent A, Shirley, Joshua D, Carlson, Erin E, Adamala, Katarzyna P, Engelhart, Aaron E

“…A teaching laboratory experiment is described where students prepare in vitro transcription reactions of a fluorescent RNA aptamer, named Broccoli, and observe…”
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Laboratory Diagnosis of Adenoviral Infections in Transplant Recipients by Shirley, Joshua D., Yao, Joseph D.

“…Adenovirus (AdV) is a common cause of mild respiratory tract and gastrointestinal tract infections in immunocompetent children and adults. Among hematopoietic…”
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Cover Feature: Comparison of Bioorthogonal β‐Lactone Activity‐Based Probes for Selective Labeling of Penicillin‐Binding Proteins (ChemBioChem 1/2021) by Brown, Nathaniel W., Shirley, Joshua D., Marshall, Andrew P., Carlson, Erin E.

“…Decision tree: The cover feature depicts the decision making process for designing bioorthogonal probes for activity‐based protein profiling. Each “branch”…”
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2118. Patient Characteristics and Clinical Outcomes of Leptotrichia spp. Bacteremia by Ranganath, Nischal, Challener, Douglas, Schuetz, Audrey, Stevens, Ryan W, Shirley, Joshua D, Shah, Aditya

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