Search Results - "Shirk, Gregg"
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E-cigarettes and their lone constituents induce cardiac arrhythmia and conduction defects in mice
Published in Nature communications (25-10-2022)“…E-cigarette use has surged, but the long-term health effects remain unknown. E-cigarette aerosols containing nicotine and acrolein, a combustion and…”
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2
Cardioprotection by postconditioning in conscious rats is limited to coronary occlusions <45 min
Published in American journal of physiology. Heart and circulatory physiology (01-11-2006)“…Brief episodes of ischemia and reperfusion after a lethal ischemic insult confer cardioprotection, a phenomenon termed "ischemic postconditioning." However,…”
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3
Atorvastatin therapy during the peri-infarct period attenuates left ventricular dysfunction and remodeling after myocardial infarction
Published in PloS one (28-09-2011)“…Although statins impart a number of cardiovascular benefits, whether statin therapy during the peri-infarct period improves subsequent myocardial structure and…”
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4
The cardioprotection of the late phase of ischemic preconditioning is enhanced by postconditioning via a COX-2-mediated mechanism in conscious rats
Published in American journal of physiology. Heart and circulatory physiology (01-10-2007)“…The present study sought to determine whether the combination of late preconditioning (PC) with postconditioning enhances the reduction in infarct size…”
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5
Abstract 4146149: Influence of Hypertension on Cardiovascular Injury of Short-term Particulate Air Pollution Exposure in Mice
Published in Circulation (New York, N.Y.) (12-11-2024)“…Abstract only Background: The WHO estimates that air pollution causes 7 million premature deaths or about 1 in 8 global deaths. Epidemiological studies…”
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6
Electronic cigarette solvents, pulmonary irritation, and endothelial dysfunction: role of acetaldehyde and formaldehyde
Published in American journal of physiology. Heart and circulatory physiology (01-04-2021)“…After more than a decade of electronic cigarette (E-cig) use in the United States, uncertainty persists regarding E-cig use and long-term cardiopulmonary…”
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7
Abstract 17126: Role of Aldehydes, Transient Receptor Potential Ankyrin 1, and Catecholamines in Electronic Cigarette-Induced Endothelial Dysfunction in Mice
Published in Circulation (New York, N.Y.) (07-11-2023)“…Abstract only Although Electronic Nicotine Delivery Systems (ENDS)-derived aerosols induce endothelial dysfunction (ED), the mechanisms and constituents…”
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Formaldehyde and the transient receptor potential ankyrin-1 contribute to electronic cigarette aerosol-induced endothelial dysfunction in mice
Published in Toxicological sciences (01-10-2024)“…Electronic nicotine delivery systems (ENDS) aerosol exposures can induce endothelial dysfunction (ED) in healthy young humans and animals. Thermal degradation…”
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9
Intracoronary Administration of Cardiac Progenitor Cells Alleviates Left Ventricular Dysfunction in Rats With a 30-Day-Old Infarction
Published in Circulation (New York, N.Y.) (19-01-2010)“…Administration of cardiac progenitor cells (CPCs) 4 hours after reperfusion ameliorates left ventricular function in rats with acute myocardial infarction…”
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10
Acute and chronic vascular effects of inhaled crotonaldehyde in mice: Role of TRPA1
Published in Toxicology and applied pharmacology (01-09-2020)“…Although crotonaldehyde (CR) is an abundant α,β-unsaturated aldehyde in mainstream cigarette smoke (MCS), the cardiovascular toxicity of inhaled CR is largely…”
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Effects of Intracoronary Infusion of Escalating Doses of Cardiac Stem Cells in Rats With Acute Myocardial Infarction
Published in Circulation. Heart failure (01-07-2015)“…Although c-kit(pos) cardiac stem cells (CSCs) preserve left ventricular (LV) function and structure after myocardial infarction, CSC doses have been chosen…”
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12
DOSE-DEPENDENT EFFECTS OF INTRACORONARY CARDIAC STEM CELLS IN RATS WITH ACUTE MYOCARDIAL INFARCTION
Published in Journal of the American College of Cardiology (17-03-2015)“…Echocardiography showed ejection fraction (EF), infarct wall thickening fraction (IW ThF), and LV end-systolic volume (LVESV) were improved significantly in…”
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13
Nitroglycerin induces late preconditioning against myocardial infarction in conscious rabbits despite development of nitrate tolerance
Published in Circulation (New York, N.Y.) (07-08-2001)“…Recent studies suggest that the late phase of ischemic preconditioning (PC) can be mimicked by pretreatment with NO donors. The ability of clinically relevant…”
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14
Hypercholesterolemia abrogates late preconditioning via a tetrahydrobiopterin-dependent mechanism in conscious rabbits
Published in Circulation (New York, N.Y.) (04-10-2005)“…Although the late phase of ischemic preconditioning (PC) is known to confer cardioprotection in healthy animal models, it is unknown whether this phenomenon…”
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15
Nicorandil induces late preconditioning against myocardial infarction in conscious rabbits
Published in American journal of physiology. Heart and circulatory physiology (01-04-2004)“…Nicorandil has been shown to induce an infarct-limiting effect similar to that induced by the early phase of ischemic preconditioning (PC). The goals of this…”
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16
Nitroglycerin induces late preconditioning against myocardial stunning via a PKC-dependent pathway
Published in The American journal of physiology (01-12-1999)“…Previous studies have shown that administration of nitric oxide (NO) donors induces a delayed cardioprotective effect indistinguishable from the late phase of…”
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Hypercholesterolemia blunts NO donor-induced late preconditioning against myocardial infarction in conscious rabbits
Published in Basic research in cardiology (01-11-2004)“…Although NO donors have been shown to confer late preconditioning (PC) against myocardial ischemia/reperfusion injury in healthy rabbits, it is unknown whether…”
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