Search Results - "Shirinbak, S."

Iron administration reduces airway hyperreactivity and eosinophilia in a mouse model of allergic asthma by Maazi, H., Shirinbak, S., Bloksma, N., Nawijn, M. C., van Oosterhout, A. J. M.

“…Summary The prevalence of allergic diseases has increased dramatically during the last four decades and is paralleled by a striking increase in iron intake by…”
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Contribution of regulatory T cells to alleviation of experimental allergic asthma after specific immunotherapy by Maazi, H., Shirinbak, S., Willart, M., Hammad, H. M., Cabanski, M., Boon, L., Ganesh, V., Baru, A. M., Hansen, G., Lambrecht, B. N., Sparwasser, T., Nawijn, M. C., van Oosterhout, A. J. M.

“…Summary Background Allergen‐specific immunotherapy (SIT) has been used since 1911, yet its mechanism of action remains to be elucidated. There is evidence…”
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Cytotoxic T lymphocyte antigen 4‐immunoglobulin G is a potent adjuvant for experimental allergen immunotherapy by Maazi, H., Shirinbak, S., Boef, L. E., Fallarino, F., Volpi, C., Nawijn, M. C., Oosterhout, A. J. M.

“…Summary Allergen‐specific immunotherapy (SIT) is the only treatment for allergic diseases that targets allergen‐specific T helper type 2 (Th2) cells, which are…”
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Activation of the Non-canonical Nf-kb Pathway by CTLA4-Ig Potentiates the Beneficial Effects of Specific Immunotherapy in a Mouse Model of Allergic Asthma by Maazi, H, Shirinbak, S, Taher, Y.A, Nawijn, M.C, van Oosterhout, A.J.M

“…[...]the activation of NF-kB upon B7 ligation by CTLA4-Ig is rate-limiting for the suppressive effects of SIT in vivo, indicating that adjuvants stimulating…”
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Il-10 Production by Cd11c+ Dendritic Cells is Critically Required for Specific Immunotherapy in a Mouse Model of Allergic Asthma by Shirinbak, S, Maazi, H, Lambrecht, B.N, Nawijn, M.C, van Oosterhout, A.J.M

“…To study the role of dendritic cells(DCs), BM-derived DCs from IL-10 deficient or wild-type mice were adoptively transferred to irradiated, sensitized and…”
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