Search Results - "Shiri, Fereshteh"

Synthesis, biological evaluation and in silico study of 4-(benzo[d]thiazole-2-yl) phenols based on 4-hydroxy coumarin as acetylcholinesterase inhibitors by Mirjalili, Bi Bi Fatemeh, Fazeli Attar, Seyedeh Azita, Shiri, Fereshteh

“…Alzheimer’s disease, characterized by cognitive decline and memory loss, is associated with decreased acetylcholine levels due to acetylcholinesterase (AChE)…”
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QSTR based on Monte Carlo approach using SMILES and graph features for toxicity toward Tetrahymena pyriformis by Rezaie-keikhaie, Nasrin, Shiri, Fereshteh, Ahmadi, Shahin, Salahinejad, Maryam

“…Tetrahymena pyriformis, due to the direct contact its cells have with the outside environment, is attractive for assessing environmental toxicant effects. We…”
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QSAR and molecular docking studies of isatin and indole derivatives as SARS 3CLpro inhibitors by Soleymani, Niousha, Ahmadi, Shahin, Shiri, Fereshteh, Almasirad, Ali

“…The 3C-like protease (3CL pro ), known as the main protease of SARS-COV, plays a vital role in the viral replication cycle and is a critical target for the…”
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Improving Tamoxifen Performance in Inducing Apoptosis and Hepatoprotection by Loading on a Dual Nanomagnetic Targeting System by Zhao, Yanfang, Ding, Wanbao, Zhang, Peixian, Deng, Lei, Long, Yi, Lu, Jiuqin, Shiri, Fereshteh, Heidari Majd, Mostafa

“…Although tamoxifen (TMX) belongs to selective estrogen receptor modulators (SERMs) and selectively binds to estrogen receptors, it affects other…”
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Methods and applications of structure based pharmacophores in drug discovery by Pirhadi, Somayeh, Shiri, Fereshteh, Ghasemi, Jahan B

“…A pharmacophore model does not describe a real molecule or a real association of functional groups but illustrates a molecular recognition of a biological…”
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Hit discovery of potential CDK8 inhibitors and analysis of amino acid mutations for cancer therapy through computer-aided drug discovery by Aghahasani, Raziye, Shiri, Fereshteh, Kamaladiny, Hossein, Haddadi, Fatemeh, Pirhadi, Somayeh

“…Cyclin-dependent kinase 8 (CDK8) has emerged as a promising target for inhibiting cancer cell function, intensifying efforts towards the development of CDK8…”
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A study of the interaction space of two lactate dehydrogenase isoforms (LDHA and LDHB) and some of their inhibitors using proteochemometrics modeling by Damavandi, Sedigheh, Shiri, Fereshteh, Emamjomeh, Abbasali, Pirhadi, Somayeh, Beyzaei, Hamid

“…Lactate dehydrogenase (LDH) is a tetramer enzyme that converts pyruvate to lactate reversibly. This enzyme becomes important because it is associated with…”
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Experimental and Theoretical Approaches to Monitor the Behavior of Bovine Liver Catalase in Interaction with a Binuclear Bismuth Complex by Alimoradi, Zahral, Shiri, Fereshteh, Shahraki, Somaye, Razmara, Zohreh, Heidari-Majd, Mostafa

“…Here, the antioxidant potency of a binuclear Bi­(III) complex {[Bi2(μ-ox)­(dipic)2(H2O)2 (taa)2].H2O, where ox2– = oxalato, dipic2– = pyridine…”
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Structural insights into the origin of phosphoinositide 3-kinase inhibition by Hariri, Safoura, Rasti, Behnam, Mirpour, Mirsasan, Vaghar-Lahijani, Gholamreza, Attar, Farnoosh, Shiri, Fereshteh

“…Class I phosphoinositide 3-kinases (PI3Ks) are currently considered as significant targets for the development of novel pharmaceuticals to treat cancers and…”
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The Relationship Between Patients’ Perceived Health Status and Trust Propensity and Privacy Calculus by Shiri, Fereshteh, Peikar, Hamid Reza, Zamani, Narges

“…Background: Patients need peace of mind to disclose their information to medical staff and with the lack of trust or in specific health status, they may avoid…”
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SMILES-based QSAR virtual screening to identify potential therapeutics for COVID-19 by targeting 3CLpro and RdRp viral proteins by Bazzi-Allahri, Faezeh, Shiri, Fereshteh, Ahmadi, Shahin, Toropova, Alla P., Toropov, Andrey A.

“…The COVID-19 pandemic has prompted the medical systems of many countries to develop effective treatments to combat the high rate of infection and death caused…”
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Alignment independent 3D-QSAR, quantum calculations and molecular docking of Mer specific tyrosine kinase inhibitors as anticancer drugs by Shiri, Fereshteh, Pirhadi, Somayeh, Ghasemi, Jahan B.

“…Mer receptor tyrosine kinase is a promising novel cancer therapeutic target in many human cancers, because abnormal activation of Mer has been implicated in…”
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Application of Multivariate Linear and Nonlinear Calibration and Classification Methods in Drug Design by Abdolmaleki, Azizeh, Ghasemi, Jahan B, Shiri, Fereshteh, Pirhadi, Somayeh

“…Data manipulation and maximum efficient extraction of useful information need a range of searching, modeling, mathematical, and statistical approaches. Hence,…”
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Discovery of new potential antimalarial compounds using virtual screening of ZINC database by Ghasemi, Jahan B, Shiri, Fereshteh, Pirhadi, Somayeh, Heidari, Zahra

“…Falcipain-3 (FP-3) is a cysteine protease of the malaria parasite Plasmodium falciparum which is a promising and attractive target enzyme for antiparasitic…”
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2D Quantitative structure-property relationship study of mycotoxins by multiple linear regression and support vector machine by Khosrokhavar, Roya, Ghasemi, Jahan Bakhsh, Shiri, Fereshteh

“…In the present work, support vector machines (SVMs) and multiple linear regression (MLR) techniques were used for quantitative structure-property relationship…”
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Binding interaction of isoxsuprine hydrochloride and levothyroxine to milk β-lactoglobulin; from the perspective of comparison by Shahraki, Somaye, Shiri, Fereshteh

“…Isoxsuprine hydrochloride (ISO) and levothyroxine (LEV) are medicines which can be utilized alone or simultaneously by pregnant women. The purpose of this work…”
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An exploratory study on application of various classification models to distinguish switchable-hydrophilicity solvents based on 3D-descriptors by Shiri, Mohammad, Shiri, Fereshteh

“…A set of solvents were classified into the switchable-hydrophilicity solvents (SHSs) and non-switchable-hydrophilicity solvents based on forming or not forming…”
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A paramagnetic oxalato-bridged binuclear copper(II) complex as an effective catalase inhibitor. Spectroscopic and molecular docking studies by Shahraki, Somaye, Razmara, Zohreh, Shiri, Fereshteh

“…A binuclear oxalato-bridged Cu complex formulated as [μ-(ox){Cu(Mebpy) (NO3) (H2O)} 2] (where Mebpy is 5,5′-dimethyl-2,2′-dipyridyl and ox is oxalate) was…”
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Three-Dimensional Quantitative Structure-Activity Relationship Analysis and Molecular Docking of some Nonpeptidic Inhibitors of Protein Tyrosine Phosphatase as Anti-Alzheimer Drugs by fereshteh shiri

“…Background & Objective: Alzheimer’s disease (AD) is a kind of neuropsychiatric disorder that gradually degrades the mental abilities. High level activity of…”
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Improving enzymatic performance of antioxidant enzyme catalase in combination with [Mn (phen)2Cl.H2O]Cl.tu complex by Shahraki, Somaye, Shiri, Fereshteh, Razmara, Zohreh

“…Efforts to synthesize metal complexes that have good biological potency, such as anti‐cancer or antioxidant properties, have expanded. In this study, an Mn…”
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