Search Results - "Shirazi, Amir N"
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Design, Synthesis, and Evaluation of Homochiral Peptides Containing Arginine and Histidine as Molecular Transporters
Published in Molecules (Basel, Switzerland) (29-06-2018)“…Linear (HR) and cyclic [HR] peptides (n = 4,5) containing alternate arginine and histidine residues were synthesized. The peptides showed 0⁻15% cytotoxicity at…”
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Synthesis of novel ciprofloxacin analogues and evaluation of their anti-proliferative effect on human cancer cell lines
Published in Bioorganic & medicinal chemistry letters (01-12-2013)“…A series of twenty two novel 1-cyclopropyl-6-fluoro-4-oxo-7-(4-substituted piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid analogues have been…”
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Design, synthesis, and evaluation of chitosan conjugated GGRGDSK peptides as a cancer cell-targeting molecular transporter
Published in International journal of biological macromolecules (01-06-2016)“…Targeting cancer cells using integrin receptor is one of the promising targeting strategies in drug delivery. In this study, we conjugated an integrin-binding…”
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Synthesis and evaluation of c-Src kinase inhibitory activity of pyridin-2(1H)-one derivatives
Published in Bioorganic chemistry (01-04-2014)“…Among eighteen pyridin-2(1H)-one derivatives synthesized, compounds 36 and 38 were found to be the most potent c-Src kinase inhibitors with IC50 values of…”
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Design, Synthesis, and Evaluation of the Kinase Inhibition Potential of Pyridylpyrimidinylaminophenyl Derivatives
Published in Archiv der Pharmazie (Weinheim) (01-04-2017)“…In view of potent kinase inhibitors for the treatment of myriad human disorders, we synthesized some structurally variant amide/cyclic amide derivatives based…”
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Microwave-assisted and scandium triflate catalyzed synthesis of tetrahydrobenzo[a]xanthen-11-ones
Published in Monatshefte für Chemie (01-02-2012)“…Synthesis of 12-aryl-8,9,10,12-tetrahydro-benzo[ a ]xanthen-11-ones was achieved by one-pot condensation of β-naphthol, substituted benzaldehydes, and…”
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