Search Results - "Shirayoshi, Y"

Refined human artificial chromosome vectors for gene therapy and animal transgenesis by Kazuki, Y, Hoshiya, H, Takiguchi, M, Abe, S, Iida, Y, Osaki, M, Katoh, M, Hiratsuka, M, Shirayoshi, Y, Hiramatsu, K, Ueno, E, Kajitani, N, Yoshino, T, Kazuki, K, Ishihara, C, Takehara, S, Tsuji, S, Ejima, F, Toyoda, A, Sakaki, Y, Larionov, V, Kouprina, N, Oshimura, M

“…Human artificial chromosomes (HACs) have several advantages as gene therapy vectors, including stable episomal maintenance, and the ability to carry large gene…”
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Correction of a genetic defect in multipotent germline stem cells using a human artificial chromosome by Kazuki, Y, Hoshiya, H, Kai, Y, Abe, S, Takiguchi, M, Osaki, M, Kawazoe, S, Katoh, M, Kanatsu-Shinohara, M, Inoue, K, Kajitani, N, Yoshino, T, Shirayoshi, Y, Ogura, A, Shinohara, T, Barrett, J C, Oshimura, M

“…Human artificial chromosomes (HACs) have several advantages as gene therapy vectors, including stable episomal maintenance that avoids insertional mutations…”
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Carvedilol Suppresses Apoptosis and Ion Channel Remodelling of HL-1 Cardiac Myocytes Expressing E334K cMyBPC by Endo, R, Bahrudin, U, Notsu, T, Tanno, S, Onohara, T, Yamaguchi, S, Ikeda, N, Surastri, B, Nakayama, Y, Ninomiya, H, Shirayoshi, Y, Inagaki, Y, Yamamoto, K, Yoshida, A, Hisatome, I

“…Besides its antiarrhythmic action, carvedilol has an activity to suppress cardiac tissue damage. However, it is unknown whether it has any effect on cellular…”
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Transcriptional activation of the anchoring protein SAP97 by heat shock factor (HSF)-1 stabilizes K(v) 1.5 channels in HL-1 cells by Ting, Y K, Morikawa, K, Kurata, Y, Li, P, Bahrudin, U, Mizuta, E, Kato, M, Miake, J, Yamamoto, Y, Yoshida, A, Murata, M, Inoue, T, Nakai, A, Shiota, G, Higaki, K, Nanba, E, Ninomiya, H, Shirayoshi, Y, Hisatome, I

“…The expression of voltage-dependent K(+) channels (K(v) ) 1.5 is regulated by members of the heat shock protein (Hsp) family. We examined whether the heat…”
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Targeted disruption of the human LIT1 locus defines a putative imprinting control element playing an essential role in Beckwith-Wiedemann syndrome by HORIKE, S.-I, MITSUYA, K, MEGURO, M, KOTOBUKI, N, KASHIWAGI, A, NOTSU, T, SCHULZ, T. C, SHIRAYOSHI, Y, OSHIMURA, M

“…Human chromosome 11p15.5 harbors an intriguing imprinted gene cluster of 1 Mb. This imprinted domain is implicated in a wide variety of malignancies and…”
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Simultaneous treatment with azelnidipine and olmesartan inhibits apoptosis of Hl-1 cardiac myocytes expressing E334k cMyBPC by Bahrudin, U, Ikeda, N, Utami, S B, Maharani, N, Morikawa, K, Li, P, Sobirin, M A, Hasegawa, A, Sakata, S, Endo, R, Rifqi, S, Shirayoshi, Y, Yamamoto, K, Ninomiya, H, Hisatome, I

“…Apoptosis appears to play an important role in the pathogenesis of hypertrophic cardiomyopathy (HCM). We have previously reported 3 HCM patients carrying the…”
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Transcriptional activation of the anchoring protein SAP97 by heat shock factor (HSF)‐1 stabilizes Kv1.5 channels in HL‐1 cells by Ting, YK, Morikawa, K, Kurata, Y, Li, P, Bahrudin, U, Mizuta, E, Kato, M, Miake, J, Yamamoto, Y, Yoshida, A, Murata, M, Inoue, T, Nakai, A, Shiota, G, Higaki, K, Nanba, E, Ninomiya, H, Shirayoshi, Y, Hisatome, I

“…BACKGROUND AND PURPOSE The expression of voltage‐dependent K+ channels (Kv) 1.5 is regulated by members of the heat shock protein (Hsp) family. We examined…”
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Proteomic signatures and aberrations of mouse embryonic stem cells containing a single human chromosome 21 in neuronal differentiation: An in vitro model of down syndrome by Kadota, M., Nishigaki, R., Wang, C.C., Toda, T., Shirayoshi, Y., Inoue, T., Gojobori, T., Ikeo, K., Rogers, M.S., Oshimura, M.

“…Neurodegeneration in fetal development of Down syndrome (DS) patients is proposed to result in apparent neuropathological abnormalities and to contribute to…”
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Functional requirement of gp130-mediated signaling for growth and survival of mouse primordial germ cells in vitro and derivation of embryonic germ (EG) cells by Koshimizu, U, Taga, T, Watanabe, M, Saito, M, Shirayoshi, Y, Kishimoto, T, Nakatsuji, N

“…Leukemia inhibitory factor (LIF) is a cytokine known to influence proliferation and/or survival of mouse primordial germ cells (PGC) in culture. The receptor…”
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Interferon-Induced Transcription of a Major Histocompatibility Class I Gene Accompanies Binding of Inducible Nuclear Factors to the Interferon Consensus Sequence by Shirayoshi, Yasuaki, Burke, Peter A., Appella, Ettore, Ozato, Keiko

“…Interferon (IFN) induces transcription of major histocompatibility class I genes by way of the conserved cis-acting regulatory element, termed the IFN…”
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Proto‐oncogene of int‐3, a mouse Notch homologue, is expressed in endothelial cells during early embryogenesis by Shirayoshi, Yasuaki, Yuasa, Yoshihiro, Suzuki, Takashi, Sugaya, Kimihiko, Kawase, Eihachiro, Ikemura, Toshimichi, Nakatsuji, Norio

“…Background: Notch and its homologues are key regulatory receptors of the cell fate decision in various developmental processes. The int‐3 oncogene was…”
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Regulation of mouse CYP1A1 gene expression by dioxin: requirement of two cis-acting elements during induction by NEUHOLD, L. A, SHIRAYOSHI, Y, OZATO, K, JONES, J. E, NEBERT, D. W

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Binding of multiple nuclear factors to the 5' upstream regulatory element of the murine major histocompatibility class I gene by SHIRAYOSHI, Y, MIYAZAKI, J, BURKE, P. A, HAMADA, K, APPELLA, E, OZATO, K

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Developmental and tissue-specific expression of nuclear proteins that bind the regulatory element of the major histocompatibility complex class I gene by BURKE, P. A, HIRSCHFELD, S, SHIRAYOSHI, Y, KASIK, J. W, HAMADA, K, APPELLA, E, OZATO, K

“…Expression of MHC class I genes varies according to developmental stage and type of tissues. To study the basis of class I gene regulation in tissues in vivo,…”
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Cadherin cell adhesion molecules with distinct binding specificities share a common structure by Shirayoshi, Y., Hatta, K., Hosoda, M., Tsunasawa, S., Sakiyama, F., Takeichi, M.

“…Ca2+‐dependent cell‐‐cell adhesion molecules, termed cadherins, are divided into subclasses with distinct tissue distributions and distinct cell‐binding…”
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Proteomics-based identification of differentially expressed genes in human gliomas: down-regulation of SIRT2 gene by Hiratsuka, Masaharu, Inoue, Toshiaki, Toda, Tosifusa, Kimura, Narimichi, Shirayoshi, Yasuaki, Kamitani, Hideki, Watanabe, Takashi, Ohama, Eisaku, Tahimic, Candice G.T, Kurimasa, Akihiro, Oshimura, Mitsuo

“…A number of chromosomal abnormalities including 19q deletions have been associated with the formation of human gliomas. In this study, we employed a…”
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Ubiquitin-Proteasome System Impairment Caused by a Missense Cardiac Myosin-binding Protein C Mutation and Associated with Cardiac Dysfunction in Hypertrophic Cardiomyopathy by Bahrudin, Udin, Morisaki, Hiroko, Morisaki, Takayuki, Ninomiya, Haruaki, Higaki, Katsumi, Nanba, Eiji, Igawa, Osamu, Takashima, Seiji, Mizuta, Einosuke, Miake, Junichiro, Yamamoto, Yasutaka, Shirayoshi, Yasuaki, Kitakaze, Masafumi, Carrier, Lucie, Hisatome, Ichiro

“…The ubiquitin-proteasome system is responsible for the disappearance of truncated cardiac myosin-binding protein C, and the suppression of its activity…”
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Negative Regulation of the Major Histocompatibility Complex Class I Promoter in Embryonal Carcinoma Cells by Flanagan, James R., Murata, Masahiro, Burke, Peter A., Shirayoshi, Yasuaki, Appella, Ettore, Sharp, Phillip A., Ozato, Keiko

“…Transcription of major histocompatibility complex (MHC) class I genes is negatively regulated in undifferentiated F9 mouse embryonal carcinoma cells via the…”
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A new mouse model for Down syndrome by Kazuki, Y, Schulz, T C, Shinohara, T, Kadota, M, Nishigaki, R, Inoue, T, Kimura, M, Kai, Y, Abe, S, Shirayoshi, Y, Oshimura, M

“…Trisomy 21 (Ts21) is the most common live-born human aneuploidy and results in a constellation of features known as Down syndrome (DS). Ts21 is a frequent…”
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ZAC, LIT1 (KCNQ1OT1) and p57KIP2 (CDKN1C) are in an imprinted gene network that may play a role in Beckwith–Wiedemann syndrome by Arima, Takahiro, Kamikihara, Tetsuya, Hayashida, Toshirou, Kato, Kiyoko, Inoue, Toshiaki, Shirayoshi, Yasuaki, Oshimura, Mitsuo, Soejima, Hidenobu, Mukai, Tunehiro, Wake, Norio

“…Loss of genomic imprinting is involved in a number of developmental abnormalities and cancers. ZAC is an imprinted gene expressed from the paternal allele of…”
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