Search Results - "Shiratsuchi, Motoaki"

Fatal Disseminated Tuberculosis during Treatment with Ruxolitinib Plus Prednisolone in a Patient with Primary Myelofibrosis: A Case Report and Review of the Literature by Tsukamoto, Yasuhiro, Kiyasu, Junichi, Tsuda, Mariko, Ikeda, Motohiko, Shiratsuchi, Motoaki, Ogawa, Yoshihiro, Yufu, Yuji

“…A 73-year-old man with primary myelofibrosis (PMF) was being treated with hydroxyurea, which was changed to ruxolitinib treatment because of worsening…”
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Isolated ACTH deficiency probably induced by autoimmune-related mechanism evoked with nivolumab by Kitajima, Keiko, Ashida, Kenji, Wada, Naoko, Suetsugu, Ryoko, Takeichi, Yukina, Sakamoto, Shohei, Uchi, Hiroshi, Matsushima, Takamitsu, Shiratsuchi, Motoaki, Ohnaka, Keizo, Furue, Masutaka, Nomura, Masatoshi

“…Nivolumab, an anti-programmed death-1 antibody, is a breakthrough treatment for several malignancies. Its specific adverse effects caused by autoimmunity are…”
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Endothelial function testing before conditioning therapy is useful for predicting transplant-related complications after allogeneic hematopoietic cell transplantation by Haji, Shojiro, Shiratsuchi, Motoaki, Takamatsu, Akiko, Tsuda, Mariko, Muta, Hiroki, Masuda, Toru, Nakashima, Yasuhiro, Ogawa, Yoshihiro

“…Background Hematopoietic stem cell transplantation (HSCT) is a useful tool for the treatment of hematologic malignancies. However, transplantation-related…”
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Killing machines: three pore-forming proteins of the immune system by McCormack, Ryan, de Armas, Lesley, Shiratsuchi, Motoaki, Podack, Eckhard R.

“…The evolution of early multicellular eukaryotes 400–500 million years ago required a defensive strategy against microbial invasion. Pore-forming proteins…”
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Rapid decrease in eGFR with concomitant use of tyrosine kinase inhibitors and renin–aldosterone–angiotensin system inhibitors in patients with chronic myelogenous leukemia by Tsuda, Mariko, Hirata, Akie, Tokunaga, Shoji, Masuda, Toru, Haji, Shojiro, Kimura, Daisaku, Nojiri, Chinatsu, Nakashima, Yasuhiro, Shiratsuchi, Motoaki, Kato, Koji, Miyamoto, Toshihiro, Akashi, Koichi, Nakashima, Naoki, Ogawa, Yoshihiro

“…Tyrosine kinase inhibitors (TKIs) have revolutionized the treatment of chronic myeloid leukemia (CML). However, TKI-related chronic renal toxicity has been…”
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Comparison between Antiemetic Effects of Palonosetron and Granisetron on Chemotherapy-Induced Nausea and Vomiting in Japanese Patients Treated with R-CHOP by Uchida, Mayako, Mori, Yasuo, Nakamura, Tsutomu, Kato, Koji, Kamezaki, Kenjiro, Takenaka, Katsuto, Shiratsuchi, Motoaki, Kadoyama, Kaori, Miyamoto, Toshihiro, Akashi, Koichi

“…In the present study, the antiemetic effect of palonosetron, not combined with dexamethasone and aprepitant, on chemotherapy-induced nausea and vomiting was…”
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Imatinib induces demethylation of miR-203 gene: An epigenetic mechanism of anti-tumor effect of imatinib by Shibuta, Tatsuki, Honda, Emi, Shiotsu, Hiromichi, Tanaka, Yuka, Vellasamy, Shalini, Shiratsuchi, Motoaki, Umemura, Tsukuru

“…Abstract MicroRNA (miRNA) is an important regulator of cellular proliferation, differentiation and death. Leukemia-specific signature of miRNAs suggests that…”
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Analysis of the variable factors influencing tacrolimus blood concentration during the switch from continuous intravenous infusion to oral administration after allogeneic hematopoietic stem cell transplantation by Suetsugu, Kimitaka, Ikesue, Hiroaki, Miyamoto, Toshihiro, Shiratsuchi, Motoaki, Yamamoto-Taguchi, Nanae, Tsuchiya, Yuichi, Matsukawa, Kumi, Uchida, Mayako, Watanabe, Hiroyuki, Akashi, Koichi, Masuda, Satohiro

“…The aim of this retrospective study was to identify variable factors affecting tacrolimus blood concentration during the switch from continuous intravenous…”
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Perforin-2 is essential for intracellular defense of parenchymal cells and phagocytes against pathogenic bacteria by McCormack, Ryan M, de Armas, Lesley R, Shiratsuchi, Motoaki, Fiorentino, Desiree G, Olsson, Melissa L, Lichtenheld, Mathias G, Morales, Alejo, Lyapichev, Kirill, Gonzalez, Louis E, Strbo, Natasa, Sukumar, Neelima, Stojadinovic, Olivera, Plano, Gregory V, Munson, George P, Tomic-Canic, Marjana, Kirsner, Robert S, Russell, David G, Podack, Eckhard R

“…Perforin-2 (MPEG1) is a pore-forming, antibacterial protein with broad-spectrum activity. Perforin-2 is expressed constitutively in phagocytes and inducibly in…”
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Transformation of follicular lymphoma to double-hit lymphoma during adjuvant chemotherapy for concurrent ovarian carcinoma by Narazaki, Taisuke, Nakashima, Yasuhiro, Tsukamoto, Yasuhiro, Tsuda, Mariko, Masuda, Toru, Kimura, Daisaku, Takamatsu, Akiko, Ohshima, Koichi, Shiratsuchi, Motoaki, Ogawa, Yoshihiro

“…The frequency of multiple primary malignant neoplasms (MPMN) is increasing due to population aging. Since consensus guidelines for the treatment of MPMN are…”
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Inhibition of Intracellular Bacterial Replication in Fibroblasts Is Dependent on the Perforin-Like Protein (Perforin-2) Encoded by Macrophage-Expressed Gene 1 by McCormack, Ryan, de Armas, Lesley R., Shiratsuchi, Motoaki, Ramos, Jahir E., Podack, Eckhard R.

“…Fibroblasts are known to eliminate intracellular bacteria, but the lethal hit of the bactericidal mechanism has not been defined. We show that primary…”
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Clinico-pathological characteristics of primary adrenal lymphomas - potential efficacy of autologous stem cell transplantation by Narazaki, Taisuke, Shiratsuchi, Motoaki, Matsushima, Takamitsu, Tsuda, Mariko, Tsukamoto, Yasuhiro, Muta, Hiroki, Masuda, Toru, Kimura, Daisaku, Takamatsu, Akiko, Yamamoto, Hidetaka, Oda, Yoshinao, Miyoshi, Hiroaki, Ohshima, Koichi, Matsuda, Yayoi, Sakamoto, Ryuichi, Nakashima, Yasuhiro, Ogawa, Yoshihiro

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Identification of a drug-response gene in multiple myeloma through longitudinal single-cell transcriptome sequencing by Masuda, Toru, Haji, Shojiro, Nakashima, Yasuhiro, Tsuda, Mariko, Kimura, Daisaku, Takamatsu, Akiko, Iwahashi, Norifusa, Umakoshi, Hironobu, Shiratsuchi, Motoaki, Kikutake, Chie, Suyama, Mikita, Ohkawa, Yasuyuki, Ogawa, Yoshihiro

“…Despite recent therapeutic advances for multiple myeloma (MM), relapse is very common. Here, we conducted longitudinal single-cell transcriptome sequencing…”
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Effectiveness and Safety of Antiemetic Aprepitant in Japanese Patients Receiving High-Dose Chemotherapy Prior to Autologous Hematopoietic Stem Cell Transplantation by Uchida, Mayako, Ikesue, Hiroaki, Miyamoto, Toshihiro, Kato, Koji, Suetsugu, Kimitaka, Ichinose, Kimiko, Hiraiwa, Hiromi, Sakurai, Asako, Takenaka, Katsuto, Muta, Tsuyoshi, Iwasaki, Hiromi, Teshima, Takanori, Shiratsuchi, Motoaki, Egashira, Nobuaki, Akashi, Koichi, Oishi, Ryozo

“…For patients receiving high-dose chemotherapy, a 5-hydroxytryptamine 3 receptor antagonist combined with dexamethasone is a standard antiemetic therapy…”
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Acquired hemophilia A associated with autoimmune pancreatitis with serum IgG4 elevation by Narazaki, Taisuke, Haji, Shojiro, Nakashima, Yasuhiro, Tsukamoto, Yasuhiro, Tsuda, Mariko, Takamatsu, Akiko, Ohno, Hirofumi, Matsushima, Takamitsu, Matsumoto, Tomoko, Nogami, Keiji, Shima, Midori, Shiratsuchi, Motoaki, Ogawa, Yoshihiro

“…A case of acquired hemophilia A (AHA) that developed in a patient with autoimmune pancreatitis (AIP) is presented. A 64-year-old woman was diagnosed with AIP…”
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Upshaw-Schulman syndrome diagnosed during pregnancy complicated by reversible cerebral vasoconstriction syndrome by Tsuda, Mariko, Shiratsuchi, Motoaki, Nakashima, Yasuhiro, Ikeda, Motohiko, Muta, Hiroki, Narazaki, Taisuke, Masuda, Toru, Kimura, Daisaku, Takamatsu, Akiko, Matsumoto, Masanori, Fujimura, Yoshihiro, Kokame, Koichi, Matsushima, Takamitsu, Ogawa, Yoshihiro

“…Upshaw-Schulman syndrome (USS) is an inherited type of thrombotic thrombocytopenic purpura (TTP) that is extremely rare, but often diagnosed during pregnancy…”
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Methotrexate‐associated lymphoproliferative disorders with angioimmunoblastic T‐cell lymphoma‐like features accompanied by gamma‐heavy chain disease in a patient with rheumatoid arthritis by Kiyasu, Junichi, Arakawa, Fumiko, Haji, Shojiro, Tachikawa, Yoshimichi, Tsuda, Mariko, Tsukamoto, Yasuhiro, Ikeda, Motohiko, Muta, Hiroki, Matsushima, Takamitsu, Miyoshi, Hiroaki, Shiratsuchi, Motoaki, Ogawa, Yoshihiro, Ohshima, Kouichi, Yufu, Yuji

“…Although gamma heavy chain disease (γ‐HCD) lesions occasionally morphologically resemble angioimmunoblastic T‐cell lymphoma (AITL), no association has been…”
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Nivolumab-induced thyroid dysfunction lacking antithyroid antibody is frequently evoked in Japanese patients with malignant melanoma by Yano, Seiichi, Ashida, Kenji, Nagata, Hiromi, Ohe, Kenji, Wada, Naoko, Takeichi, Yukina, Hanada, Yuki, Ibayashi, Yuta, Wang, Lixiang, Sakamoto, Shohei, Sakamoto, Ryuichi, Uchi, Hiroshi, Shiratsuchi, Motoaki, Furue, Masutaka, Nomura, Masatoshi, Ogawa, Yoshihiro

“…Nivolumab, an anti-programmed cell death-1 monoclonal antibody, has improved the survival of patients with malignant melanoma. Despite its efficacy, nivolumab…”
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Achievement of disease control with donor-derived EB virus-specific cytotoxic T cells after allogeneic peripheral blood stem cell transplantation for aggressive NK-cell leukemia by Haji, Shojiro, Shiratsuchi, Motoaki, Matsushima, Takamitsu, Takamatsu, Akiko, Tsuda, Mariko, Tsukamoto, Yasuhiro, Tanaka, Emi, Ohno, Hirofumi, Fujioka, Eriko, Ishikawa, Yuriko, Imadome, Ken-Ichi, Ogawa, Yoshihiro

“…Aggressive NK-cell leukemia (ANKL) is characterized by systemic infiltration of Epstein-Barr virus (EBV)-associated natural killer cells and poor prognosis. We…”
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Combination of high-dose melphalan and bortezomib as conditioning regimen for autologous peripheral blood stem cell transplantation in multiple myeloma by Miyamoto, Toshihiro, Yoshimoto, Goichi, Kamimura, Tomohiko, Muta, Tsuyoshi, Takashima, Shuichiro, Ito, Yoshikiyo, Shiratsuchi, Motoaki, Choi, Ilseung, Kato, Koji, Takenaka, Katsuto, Iwasaki, Hiromi, Takamatsu, Yasushi, Teshima, Takanori, Akashi, Koichi

“…Bortezomib and melphalan have synergistic effects against multiple myeloma (MM) cells. We conducted a pilot study on the combination of bortezomib and…”
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