Search Results - "Shirato, Haruki"

Comparison of supportive regulatory measures for pediatric medical device development in Japan and the United States by Takahashi, Sara, Iwasaki, Kiyotaka, Shirato, Haruki, Ho, Mami, Umezu, Mitsuo

“…Further development of medical devices for children is required in Japan, but the development of such devices is delayed compared to that of medical devices…”
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Practice and Safety of Static Balloon Atrial Septostomy Based on a Nationwide Registry Data by Inuzuka, Ryo, Tachimori, Hisateru, Kim, Sung-Hae, Matsui, Hikoro, Kobayashi, Tohru, Kato, Atsuko, Fujii, Takanari, Ho, Mami, Morikawa, Hanako, Takahashi, Sara, Shirato, Haruki, Haishima, Yuji, Okamoto, Yoshihiro, Sakoda, Hideyuki, Tomita, Hideshi

“…Background: Balloon atrial septostomy (BAS) is an essential catheterization procedure for congenital heart lesions. Recently, a balloon catheter for static BAS…”
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Learning Curve for Transcatheter Aortic Valve Implantation Under a Controlled Introduction System　― Initial Analysis of a Japanese Nationwide Registry by Handa, Nobuhiro, Kumamaru, Hiraku, Torikai, Kei, Kohsaka, Shun, Takayama, Morimasa, Kobayashi, Junjiro, Ogawa, Hisao, Shirato, Haruki, Ishii, Kensuke, Koike, Kazuhisa, Yokoyama, Yoshimasa, Miyata, Hiroaki, Motomura, Noboru, Sawa, Yoshiki, on behalf of Japanese TAVR Registry Participants

“…Background:The introduction of transcatheter aortic valve implantation (TAVI) into Japan was strictly controlled to optimize patient outcomes. The goal of this…”
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Independent Factors for In-Hospital Death Following Drug-Eluting Stent Thrombosis From the Japanese Adverse Event Report System by Mitsutake, Yoshiaki, Konishi, Akihide, Handa, Nobuhiro, Ho, Mami, Shirato, Haruki, Ito, Takuya, Koike, Kazuhisa, Mochizuki, Shuichi, Ishii, Kensuke

“…Background:Stent thrombosis (ST) is a serious complication after drug-eluting stents (DES) implantation. To identify the risk factors of mortality following…”
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First Approval of Improved Medical Device Conditional on Use-Result Survey in Japan　― Regulatory Review of Polymer-Free Drug-Coated BioFreedom Coronary Stent by Konishi, Akihide, Ho, Mami, Shirai, Yuko, Shirato, Haruki

“…A prospective randomized clinical trial showed that the BioFreedom stent (Biosensors International), which is a polymer-free and carrier-free drug-coated…”
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Differences in clinical outcomes between pre- and post-marketing clinical study following paclitaxel-coated balloon catheter treatment for coronary in-stent restenosis: from the Japanese regulatory viewpoint by Mitsutake, Yoshiaki, Konishi, Akihide, Shiba, Takeshi, Ito, Takuya, Ho, Mami, Shirato, Haruki

“…In 2013, a drug-coated balloon catheter (DCB) (SeQuent Please) for the treatment of coronary in-stent restenosis (ISR) was approved in Japan. The pre-marketing…”
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Recent Least Burdensome Approach for the Approval of Innovative Medical Devices in Japan -Regulatory Approval Review of an Everolimus-eluting Bioresorbable Scaffold by Konishi, Akihide, Ho, Mami, Mitsutake, Yoshiaki, Ouchi, Takashi, Nakamura, Masato, Shirato, Haruki

“…Although a domestic trial in Japan revealed that Absorb bioresorbable vascular scaffold (BVS) has no inferiority to everolimus-eluting stent (EES) cohort in…”
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Regulatory approval review of transcatheter mitral valve repair – Difference in the indication between the USA and Japan by Konishi, Akihide, Ho, Mami, Ouchi, Takashi, Mitsutake, Yoshiaki, Shirato, Haruki

“…•MitraClip provides significant clinical improvements in DMR and FMR patients.•Informative data indicated TMVR using MitraClip did not increase mortality…”
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A Jumonji (Jarid2) Protein Complex Represses cyclin D1 Expression by Methylation of Histone H3-K9 by Shirato, Haruki, Ogawa, Satoko, Nakajima, Kuniko, Inagawa, Masayo, Kojima, Mizuyo, Tachibana, Makoto, Shinkai, Yoichi, Takeuchi, Takashi

“…Covalent modifications of histone tails have critical roles in regulating gene expression. Previously, we identified the jumonji (jmj, Jarid2) gene, the jmjC…”
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Coordinated regulation of differentiation and proliferation of embryonic cardiomyocytes by a jumonji (Jarid2)-cyclin D1 pathway by Nakajima, Kuniko, Inagawa, Masayo, Uchida, Chiharu, Okada, Kumiko, Tane, Shoji, Kojima, Mizuyo, Kubota, Misae, Noda, Masatsugu, Ogawa, Satoko, Shirato, Haruki, Sato, Michio, Suzuki-Migishima, Rika, Hino, Toshiaki, Satoh, Yukio, Kitagawa, Masatoshi, Takeuchi, Takashi

“…In general, cell proliferation and differentiation show an inverse relationship, and are regulated in a coordinated manner during development. Embryonic…”
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Scapinin, a Putative Protein Phosphatase-1 Regulatory Subunit Associated with the Nuclear Nonchromatin Structure by Sagara, Junji, Higuchi, Tsukasa, Hattori, Yukiko, Moriya, Mie, Sarvotham, Haritha, Shima, Hiroshi, Shirato, Haruki, Kikuchi, Kunimi, Taniguchi, Shunichiro

“…It is thought that the nuclear nonchromatin structures, such as the nuclear matrix and lamina, play regulatory roles in gene expression. In this study, we…”
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Identification and Characterization of a Novel Protein Inhibitor of Type 1 Protein Phosphatase by Shirato, Haruki, Shima, Hiroshi, Sakashita, Gyosuke, Nakano, Takeshi, Ito, Masaaki, Lee, Ernest Y. C, Kikuchi, Kunimi

“…We have isolated human cDNA for a novel type 1 protein phosphatase (PP1) inhibitory protein, named inhibitor-4 (I-4), from a cDNA library of germ cell tumors…”
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Japan-USA Orbital Atherectomy for Calcific Coronary Lesions: COAST Study, a Harmonization by Doing Proof-of-Concept: The Japanese and US Regulatory Perspective by Iwamoto, Shin, Ohashi, Moe, Shirato, Haruki, Ho, Mami, Malone, Misti, Cavanaugh, Kenneth

“…Regulatory approval processes for medical devices in Japan and the United States of America (US) often require similar clinical trials to establish safety and…”
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Independent Factors for In-Hospital Death Following Drug-Eluting Stent Thrombosis From the Japanese Adverse Event Report System by Mitsutake, Yoshiaki, Konishi, Akihide, Handa, Nobuhiro, Ho, Mami, Shirato, Haruki, Ito, Takuya, Koike, Kazuhisa, Mochizuki, Shuichi, Ishii, Kensuke

“…Background:Stent thrombosis (ST) is a serious complication after drug-eluting stents (DES) implantation. To identify the risk factors of mortality following…”
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Recent Least Burdensome Approach for the Approval of Innovative Medical Devices in Japan -Regulatory Approval Review of an Everolimus-eluting Bioresorbable Scaffold by Konishi, Akihide, Ho, Mami, Mitsutake, Yoshiaki, Ouchi, Takashi, Nakamura, Masato, Shirato, Haruki

“…Although a domestic trial in Japan revealed that Absorb bioresorbable vascular scaffold (BVS) has no inferiority to everolimus-eluting stent (EES) cohort in…”
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Practice and Safety of Static Balloon Atrial Septostomy Based on a Nationwide Registry Data by Inuzuka, Ryo, Tachimori, Hisateru, Kim, Sung-Hae, Matsui, Hikoro, Kobayashi, Tohru, Kato, Atsuko, Fujii, Takanari, Ho, Mami, Morikawa, Hanako, Takahashi, Sara, Shirato, Haruki, Haishima, Yuji, Okamoto, Yoshihiro, Sakoda, Hideyuki, Tomita, Hideshi

“…Background: Balloon atrial septostomy (BAS) is an essential catheterization procedure for congenital heart lesions. Recently, a balloon catheter for static BAS…”
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jumonji Downregulates Cardiac Cell Proliferation by Repressing cyclin D1 Expression by Toyoda, Masashi, Shirato, Haruki, Nakajima, Kuniko, Kojima, Mizuyo, Takahashi, Miho, Kubota, Misae, Suzuki-Migishima, Rika, Motegi, Yoshiko, Yokoyama, Minesuke, Takeuchi, Takashi

“…Spatiotemporal regulation of cell proliferation is necessary for normal tissue development. The molecular mechanisms, especially the signaling pathways…”
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Expression in hepatomas and chromosomal localization of rat protein phosphatase 5 gene by Shirato, H, Shima, H, Nakagama, H, Fukuda, H, Watanabe, Y, Ogawa, K, Matsuda, Y, Kikuchi, K

“…The serine/threonine protein phosphatase type 5 (PP5) gene expression was ubiquitously observed among all the tissues examined, but being at the lowest level…”
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Impaired differentiation of fetal hepatocytes in homozygous jumonji mice by Anzai, Hiroko, Kamiya, Akihide, Shirato, Haruki, Takeuchi, Takashi, Miyajima, Atsushi

“…Homozygous jumonji ( jmj −/ jmj −) mice were previously shown to exhibit hepatic hypoplasia and defective hematopoiesis in the liver and die at around…”
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