Search Results - "Shirasaki, Natsumi"
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Control of division in Chlamydomonas by cyclin B/CDKB1 and the anaphase-promoting complex
Published in PLoS genetics (18-08-2022)“…In yeast and animals, cyclin B binds and activates the cyclin-dependent kinase (‘CDK’) CDK1 to drive entry into mitosis. We show that CYCB1, the sole cyclin B…”
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Forkhead box protein O1 (FoxO1) knockdown accelerates the eicosapentaenoic acid (EPA)-mediated Selenop downregulation independently of sterol regulatory element-binding protein-1c (SREBP-1c) in H4IIEC3 hepatocytes
Published in ENDOCRINE JOURNAL (01-01-2022)“…Selenoprotein P is upregulated in type 2 diabetes, causing insulin and exercise resistance. We have previously reported that eicosapentaenoic acid (EPA)…”
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3
The osteopontin-CD44 axis in hepatic cancer stem cells regulates IFN signaling and HCV replication
Published in Scientific reports (03-09-2018)“…Osteopontin (OPN) is involved in cell proliferation, migration, inflammation, and tumor progression in various tissues. OPN induces stemness by interacting…”
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Peretinoin, an Acyclic Retinoid, Inhibits Hepatitis B Virus Replication by Suppressing Sphingosine Metabolic Pathway In Vitro
Published in International journal of molecular sciences (23-01-2018)“…Hepatocellular carcinoma (HCC) frequently develops from hepatitis C virus (HCV) and hepatitis B virus (HBV) infection. We previously reported that peretinoin,…”
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5
Insulin Suppresses Ubiquitination via the Deubiquitinating Enzyme Ubiquitin-Specific Protease 14, Independent of Proteasome Activity in H4IIEC3 Hepatocytes
Published in The Journal of pharmacology and experimental therapeutics (01-04-2023)“…Ubiquitin-proteasome dysfunction contributes to obesity-related metabolic disorders, such as diabetes and fatty liver disease. However, the regulation of…”
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Eicosapentaenoic acid down-regulates expression of the selenoprotein P gene by inhibiting SREBP-1c protein independently of the AMP-activated protein kinase pathway in H4IIEC3 hepatocytes
Published in The Journal of biological chemistry (30-06-2017)“…Selenoprotein P (encoded by SELENOP in humans, Selenop in rat), a liver-derived secretory protein, induces resistance to insulin and vascular endothelial…”
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Leukocyte cell-derived chemotaxin 2 is an antiviral regulator acting through the proto-oncogene MET
Published in Nature communications (08-06-2022)“…Retinoic acid-inducible gene (RIG)-I is an essential innate immune sensor that recognises pathogen RNAs and induces interferon (IFN) production. However,…”
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Rapid response of the steatosis-sensing hepatokine LECT2 during diet-induced weight cycling in mice
Published in Biochemical and biophysical research communications (23-09-2016)“…Dieting often leads to body weight cycling involving repeated weight loss and regain. However, little information is available regarding rapid-response serum…”
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Forkhead box protein O1 (FoxO1) knockdown accelerates the eicosapentaenoic acid (EPA)-mediated Selenop downregulation independently of sterol regulatory element-binding protein-1c (SREBP-1c) in H4IIEC3 hepatocytes
Published in Endocrine Journal (2022)“…Selenoprotein P is upregulated in type 2 diabetes, causing insulin and exercise resistance. We have previously reported that eicosapentaenoic acid (EPA)…”
Get full text
Journal Article