Search Results - "Shirane, Daiki"

Development of an Alcohol Dilution–Lyophilization Method for Preparing Lipid Nanoparticles Containing Encapsulated siRNA by Shirane, Daiki, Tanaka, Hiroki, Nakai, Yuta, Yoshioka, Hiroki, Akita, Hidetaka

“…Systems for delivering nucleic acids are now fundamental technologies for realizing personalized medicine. Among the various nucleic acid delivery systems that…”
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Self‐Degradable Lipid‐Like Materials Based on “Hydrolysis accelerated by the intra‐Particle Enrichment of Reactant (HyPER)” for Messenger RNA Delivery by Tanaka, Hiroki, Takahashi, Tatsunari, Konishi, Manami, Takata, Nae, Gomi, Masaki, Shirane, Daiki, Miyama, Ryo, Hagiwara, Shinya, Yamasaki, Yuki, Sakurai, Yu, Ueda, Keisuke, Higashi, Kenjirou, Moribe, Kunikazu, Shinsho, Eiji, Nishida, Ruka, Fukuzawa, Kaori, Yonemochi, Etsuo, Okuwaki, Koji, Mochizuki, Yuji, Nakai, Yuta, Tange, Kota, Yoshioka, Hiroki, Tamagawa, Shinya, Akita, Hidetaka

“…RNA‐based therapeutics is a promising approach for curing intractable diseases by manipulating various cellular functions. For eliciting RNA (i.e., mRNA and…”
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Ready-to-Use-Type Lyophilized Lipid Nanoparticle Formulation for the Postencapsulation of Messenger RNA by Tanaka, Hiroki, Hagiwara, Shinya, Shirane, Daiki, Yamakawa, Takuma, Sato, Yuka, Matsumoto, Chika, Ishizaki, Kota, Hishinuma, Miho, Chida, Katsuyuki, Sasaki, Kasumi, Yonemochi, Etsuo, Ueda, Keisuke, Higashi, Kenjirou, Moribe, Kunikazu, Tadokoro, Takashi, Maenaka, Katsumi, Taneichi, Sakura, Nakai, Yuta, Tange, Kota, Sakurai, Yu, Akita, Hidetaka

“…Based on the clinical success of an in vitro transcribed mRNA (IVT-mRNA) that is encapsulated in lipid nanoparticles (mRNA-LNPs), there is a growing demand by…”
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Development of an Alcohol Dilution-Lyophilization Method for the Preparation of mRNA-LNPs with Improved Storage Stability by Shirane, Daiki, Tanaka, Hiroki, Sakurai, Yu, Taneichi, Sakura, Nakai, Yuta, Tange, Kota, Ishii, Itsuko, Akita, Hidetaka

“…The lipid nanoparticle (LNP) is one of the promising nanotechnologies for the delivery of RNA molecules, such as small interfering RNA (siRNA) and messenger…”
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Effects on Metabolism in Astrocytes Caused by cGAMP, Which Imitates the Initial Stage of Brain Metastasis by Okawa, Toya, Hara, Kurumi, Goto, Momoko, Kikuchi, Moe, Kogane, Masataka, Hatakeyama, Hiroto, Tanaka, Hiroki, Shirane, Daiki, Akita, Hidetaka, Hisaka, Akihiro, Sato, Hiromi

“…The second messenger 2'3'-cyclic-GMP-AMP (cGAMP) is thought to be transmitted from brain carcinomas to astrocytes via gap junctions, which functions to promote…”
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Development of a Ready-to-Use-Type RNA Vaccine Carrier Based on an Intracellular Environment-Responsive Lipid-like Material with Immune-Activating Vitamin E Scaffolds by Anindita, Jessica, Tanaka, Hiroki, Oyama, Ryotaro, Hagiwara, Shinya, Shirane, Daiki, Taneichi, Sakura, Nakai, Yuta, Tange, Kota, Hatakeyama, Hiroto, Sakurai, Yu, Akita, Hidetaka

“…Because of its efficient and robust gene transfer capability, messenger RNA (mRNA) has become a promising tool in various research fields. The lipid…”
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Preparation of envelope-type lipid nanoparticles containing gold nanorods for photothermal cancer therapy by Paraiso, West Kristian D., Tanaka, Hiroki, Sato, Yusuke, Shirane, Daiki, Suzuki, Noriyuki, Ogra, Yasumitsu, Tange, Kota, Nakai, Yuta, Yoshioka, Hiroki, Harashima, Hideyoshi, Akita, Hidetaka

“…[Display omitted] •Gold nanorods were encapsulated in a multifunctional envelope-type nano device (AuNR-MEND).•Heat production after NIR irradiation of…”
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