Search Results - "Shirali, Anushree C."

Immune checkpoint inhibitor nephrotoxicity: what do we know and what should we do? by Perazella, Mark A, Shirali, Anushree C

“…Immune checkpoint inhibitors have dramatically improved cancer therapy for many patients. These humanized monoclonal antibodies against various immune…”
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Nephrotoxicity of Cancer Immunotherapies: Past, Present and Future by Perazella, Mark A, Shirali, Anushree C

“…Nephrotoxicity from cancer therapies is common and increasingly encountered in clinical practice, such that the subfield of "onco-nephrology" has emerged…”
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Association of Acute Interstitial Nephritis With Programmed Cell Death 1 Inhibitor Therapy in Lung Cancer Patients by Shirali, Anushree C., MD, Perazella, Mark A., MD, Gettinger, Scott, MD

“…Immune checkpoint inhibitors that target the programmed death 1 (PD-1) signaling pathway have recently been approved for use in advanced pretreated non–small…”
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Cardiorenal complications of immune checkpoint inhibitors by Sury, Krishna, Perazella, Mark A., Shirali, Anushree C.

“…The development of immune checkpoint inhibitors (ICIs) has driven a revolutionary change in cancer treatment. Although traditional chemotherapeutic agents…”
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Chemotherapy-Associated Thrombotic Microangiopathy by Aklilu, Abinet M, Shirali, Anushree C

“…Thrombotic microangiopathy (TMA) is a syndrome of microangiopathic hemolytic anemia and thrombocytopenia with end-organ dysfunction. Although the advent of…”
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Management of Cardiovascular Disease in Renal Transplant Recipients by Shirali, Anushree C, Bia, Margaret J

“…Cardiovascular disease is a major cause of graft loss and the leading cause of death in renal transplant recipients. Although there are robust data on the…”
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Mortality after acute kidney injury and acute interstitial nephritis in patients prescribed immune checkpoint inhibitor therapy by Baker, Megan L, Yamamoto, Yu, Perazella, Mark A, Dizman, Nazli, Shirali, Anushree C, Hafez, Navid, Weinstein, Jason, Simonov, Michael, Testani, Jeffrey M, Kluger, Harriet M, Cantley, Lloyd G, Parikh, Chirag R, Wilson, F Perry, Moledina, Dennis G

“…In patients receiving immune checkpoint inhibitor (ICI) therapy, acute kidney injury (AKI) is common, and can occur either from kidney injury unrelated to ICI…”
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Onconephrology: Core Curriculum 2023 by Yarandi, Niloufarsadat, Shirali, Anushree C

“…Onconephrology focuses on management of kidney disease in cancer, which manifests itself in a variety of clinical syndromes, including acute kidney injury,…”
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Onco-Nephrology: Kidney Disease in the Cancer Patient by Yarandi, Niloufarsadat, Shirali, Anushree C

“…Patients with cancer may develop kidney disease with a variety of different clinical manifestations including acute kidney injury, chronic kidney disease,…”
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Gene Expression Profiling in Kidney Transplant Recipients on Immune Checkpoint Inhibitors: More than Meets the Eye by Jethwani, Priyanka, Shirali, Anushree C

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Clinical Features and Outcomes of Immune Checkpoint Inhibitor-Associated AKI: A Multicenter Study by Cortazar, Frank B, Kibbelaar, Zoe A, Glezerman, Ilya G, Abudayyeh, Ala, Mamlouk, Omar, Motwani, Shveta S, Murakami, Naoka, Herrmann, Sandra M, Manohar, Sandhya, Shirali, Anushree C, Kitchlu, Abhijat, Shirazian, Shayan, Assal, Amer, Vijayan, Anitha, Renaghan, Amanda DeMauro, Ortiz-Melo, David I, Rangarajan, Sunil, Malik, A Bilal, Hogan, Jonathan J, Dinh, Alex R, Shin, Daniel Sanghoon, Marrone, Kristen A, Mithani, Zain, Johnson, Douglas B, Hosseini, Afrooz, Uprety, Deekchha, Sharma, Shreyak, Gupta, Shruti, Reynolds, Kerry L, Sise, Meghan E, Leaf, David E

“…Despite increasing recognition of the importance of immune checkpoint inhibitor-associated AKI, data on this complication of immunotherapy are sparse. We…”
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Is Rechallenge Appropriate in Patients that Develop Immune Checkpoint Inhibitor-Associated AKI?: COMMENTARY by Shirali, Anushree C

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Drug-induced impairment of renal function by Pazhayattil, George Sunny, Shirali, Anushree C

“…Pharmaceutical agents provide diagnostic and therapeutic utility that are central to patient care. However, all agents also carry adverse drug effect profiles…”
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How Sweet It Is: A Perspective on the Potential Anti-Tumor Role for SGLT2 Inhibitors by Gunasekaran, Deepthi, Shirali, Anushree C

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Exploring the Present and Imagining the Future Landscape of Onconephrology by Aklilu, Abinet M, Shirali, Anushree C

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Impaired NLRP3 inflammasome function in elderly mice during influenza infection is rescued by treatment with nigericin by Stout-Delgado, Heather W, Vaughan, Sarah E, Shirali, Anushree C, Jaramillo, Richard J, Harrod, Kevin S

“…The NLRP3 inflammasome is activated in the lung during influenza viral infection; however, the impact of aging on inflammasome function during influenza…”
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Age-enhanced endoplasmic reticulum stress contributes to increased Atg9A inhibition of STING-mediated IFN-β production during Streptococcus pneumoniae infection by Mitzel, Dana N, Lowry, Virginia, Shirali, Anushree C, Liu, Yushi, Stout-Delgado, Heather W

“…Pneumococcal infections remain a leading cause of death in persons ≥ 65 y of age. Recent reports have illustrated detrimental changes in the endoplasmic…”
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We use Continuous Renal Replacement Therapy for Overdoses and Intoxications by Cabrera, Valerie Jorge, Shirali, Anushree C.

“…Extracorporeal modalities for the removal of drugs and toxins are indicated for the treatment of overdoses and intoxications. Well‐established modalities…”
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Aging promotes neutrophil-induced mortality by augmenting IL-17 production during viral infection by Stout-Delgado, Heather W, Du, Wei, Shirali, Anushree C, Booth, Carmen J, Goldstein, Daniel R

“…Morbidity and mortality associated with viral infections increase with age, although the underlying mechanisms are unclear. Here, we investigated whether aging…”
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Tracking the Toll of Kidney Disease by SHIRALI, Anushree C, GOLDSTEIN, Daniel R

“…Since the discovery of the Toll-like receptors and their crucial role as modulators of innate immunity, there has been increasing appreciation of their role in…”
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