Search Results - "Shirahata, Mitsuaki"
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Genomic characterization of primary central nervous system lymphoma
Published in Acta neuropathologica (01-06-2016)“…Primary central nervous system lymphoma (PCNSL) is a rare malignancy confined to the central nervous system (CNS), and majority of PCNSL is pathologically…”
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Clinical significance and pitfalls of human chorionic gonadotropin-related tumor markers for intracranial germinomas
Published in Child's nervous system (01-04-2023)“…Purpose Measuring serum and cerebrospinal fluid human chorionic gonadotropin (hCG) is essential for the diagnosis of intracranial germ cell tumors. There are…”
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Metastatic Brain Tumors
Published in Brain and nerve = Shinkei kenkyū no shinpo (01-01-2021)“…Metastatic brain tumors are malignant lesions that spread to the brain from a primary neoplasm such as cancer or sarcoma located in other body organs. Brain…”
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Role of proliferative marker index and KBTBD4 mutation in the pathological diagnosis of pineal parenchymal tumors
Published in Brain tumor pathology (01-07-2022)“…Pineal parenchymal tumors (PPTs) are clinically rare and a biopsy is often required for a definitive diagnosis. To improve the accuracy of histological…”
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Droplet digital PCR assay for detecting TERT promoter mutations in patients with glioma
Published in Brain tumor pathology (01-07-2021)“…Two hot spot mutations (C228T, C250T) in the telomerase reverse transcriptase ( TERT ) gene are frequently identified in glioblastoma and oligodendroglioma…”
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Miliary Tuberculosis during R-MPV Therapy in an Elderly Patient with Primary Central Nerve System Lymphoma: A Case Report
Published in Case reports in oncology (29-09-2023)“…Abstract Most elderly patients with tuberculosis (TB) have previously been infected with Mycobacterium tuberculosis, which remains dormant in the body for…”
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An Epidermoid Cyst of the Thoracic Spine in an Elderly Patient
Published in World neurosurgery (01-07-2019)“…Spinal epidermoid cysts are very rare tumors, especially in the thoracic spine; they represent 0.8% of all spinal epidermoids. In adult cases, they are often…”
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Unique pathological findings of astroblastoma with MN1 alteration in a patient with late recurrence
Published in Brain tumor pathology (01-07-2021)“…Astroblastoma is an extremely rare brain tumor that has recently attracted attention owing to its association with MN1 gene alteration. However, its long-term…”
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Immunotherapy of Nivolumab with Dendritic Cell Vaccination Is Effective against Intractable Recurrent Primary Central Nervous System Lymphoma: A Case Report
Published in Neurologia medico-chirurgica (2017)“…We report effective treatment with nivolumab of a patient with recurrent primary central nervous system lymphoma (PCNSL) after multiple therapies. A…”
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Endogenous tenascin‐C enhances glioblastoma invasion with reactive change of surrounding brain tissue
Published in Cancer science (01-08-2009)“…Tenascin‐C is an extracellular matrix glycoprotein implicated in embryogenesis, wound healing and tumor progression. We previously revealed that tenascin‐C…”
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Duration between onset and diagnosis in central nervous system tumors: Impact on prognosis and functional outcome
Published in Pediatrics international (01-12-2014)“…Background The initial presentation of central nervous system (CNS) tumors in children frequently mimics other more common and less serious conditions,…”
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Prognostic prediction of glioblastoma by quantitative assessment of the methylation status of the entire MGMT promoter region
Published in BMC cancer (30-08-2014)“…O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation is reported to be a prognostic and predictive factor of alkylating chemotherapy for…”
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Gene Expression-Based Molecular Diagnostic System for Malignant Gliomas Is Superior to Histological Diagnosis
Published in Clinical cancer research (15-12-2007)“…Purpose: Current morphology-based glioma classification methods do not adequately reflect the complex biology of gliomas, thus limiting their prognostic…”
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Intraventricular Hemorrhage From a Glioblastoma in the Medulla Oblongata of an Adolescent: A Potential Diagnostic Pitfall
Published in Pediatric neurology (01-12-2015)Get full text
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Using gene expression profiling to identify a prognostic molecular spectrum in gliomas
Published in Cancer science (01-01-2009)“…Histopathological classification of gliomas is often clinically inadequate due to the diversity of tumors that fall within the same class. The goal of the…”
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Malignant transformation of germinoma 14 years after onset: Favorable efficacy of oral etoposide
Published in Pediatrics international (01-06-2015)“…We report the case of a 19‐year‐old woman with a highly malignant intracranial germ cell tumor (GCT) that developed 14 years after treatment for…”
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Rapidly Progressing Intramedullary Spinal Cord Abscess: A Case Report
Published in NMC Case Report Journal (31-12-2024)“…Intramedullary spinal cord abscess is a rare and severe infectious disease characterized by devastating neurological deficits. We report a case of cervical…”
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Conversion of a molecular classifier obtained by gene expression profiling into a classifier based on real-time PCR: a prognosis predictor for gliomas
Published in BMC genomics (10-11-2010)“…The advent of gene expression profiling was expected to dramatically improve cancer diagnosis. However, despite intensive efforts and several successful…”
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Brainstem oligodendroglial tumors in children: two case reports and review of literatures
Published in Child's nervous system (01-03-2015)Get full text
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Successful Treatment of a CNS Tumor with BCOR Internal Tandem Duplication: A Case Report
Published in NMC Case Report Journal (31-12-2023)“…A central nervous system (CNS) tumor with BCL-6 co-repressor (BCOR) internal tandem duplication (CNS tumor with BCOR ITD) is a rare tumor classified as an…”
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