Search Results - "Shipp, Annette M"

Triclosan: A critical review of the experimental data and development of margins of safety for consumer products by Rodricks, Joseph V., Swenberg, James A., Borzelleca, Joseph F., Maronpot, Robert R., Shipp, Annette M.

“…Triclosan (2,4,4′-trichloro-2′-hydroxy-diphenyl ether) is an antibacterial compound that has been used in consumer products for about 40 years. The…”
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Analysis of genomic dose-response information on arsenic to inform key events in a mode of action for carcinogenicity by Gentry, P. Robinan, McDonald, Tracy B, Sullivan, Dexter E, Shipp, Annette M, Yager, Janice W, Clewell, Harvey J. III

“…A comprehensive literature search was conducted to identify information on gene expression changes following exposures to inorganic arsenic compounds. This…”
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Influence of prenatal mercury exposure upon scholastic and psychological test performance: benchmark analysis of a New Zealand cohort by Crump, K S, Kjellström, T, Shipp, A M, Silvers, A, Stewart, A

“…This paper presents benchmark (BMD) calculations and additional regression analyses of data from a study in which scores from 26 scholastic and psychological…”
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Analysis of in vivo mutation data can inform cancer risk assessment by Moore, Martha M., Heflich, Robert H., Haber, Lynne T., Allen, Bruce C., Shipp, Annette M., Kodell, Ralph L.

“…Under the new U.S. Environmental Protection Agency (EPA) Cancer Risk Assessment Guidelines [U.S. EPA, 2005. Guidelines for Carcinogen Risk Assessment…”
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Formaldehyde exposure and leukemia: Critical review and reevaluation of the results from a study that is the focus for evidence of biological plausibility by Gentry, P. Robinan, Rodricks, Joseph V., Turnbull, Duncan, Bachand, Annette, Van Landingham, Cynthia, Shipp, Annette M., Albertini, Richard J., Irons, Richard

“…Abstract A recent study (Zhang et al., 2010) has provided results attributed to aneuploidy in circulating stem cells that has been characterized as providing…”
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Physiologically Based Pharmacokinetic Modeling of Arsenic in the Mouse by Gentry, P. Robinan, Covington, Tammie R., Mann, Sabine, Shipp, Annette M., Yager, Janice W., Clewell III, Harvey J.

“…A remarkable feature of the carcinogenicity of inorganic arsenic is that while human exposures to high concentrations of inorganic arsenic in drinking water…”
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Exposure Assessment and Risk Characterization for Perfluorooctanoate in Selected Consumer Articles by Washburn, Stephen T, Bingman, Timothy S, Braithwaite, Scott K, Buck, Robert C, Buxton, L. William, Clewell, Harvey J, Haroun, Lynne A, Kester, Janet E, Rickard, Robert W, Shipp, Annette M

“…An exposure assessment and risk characterization was conducted to better understand the potential human health significance of trace levels of…”
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Challenges in the application of quantitative approaches in risk assessment: a case study with di-(2-ethylhexyl)phthalate by Gentry, P. Robinan, Clewell, Harvey J., Clewell, Rebecca, Campbell, Jerry, Van Landingham, Cynthia, Shipp, Annette M.

“…The constantly evolving science of risk assessment is currently faced with many challenges, not only from the interpretation of the volume of data being…”
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Evaluation of the Uncertainty in an Oral Reference Dose for Methylmercury Due to Interindividual Variability in Pharmacokinetics by Clewell, Harvey J., Gearhart, Jeffery M., Gentry, P. Robinan, Covington, Tammie R., VanLandingham, Cynthia B., Crump, Kenny S., Shipp, Annette M.

“…An analysis of the uncertainty in guidelines for the ingestion of methylmercury (MeHg) due to human pharmacokinetic variability was conducted using a…”
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A Pharmacokinetic Model of the Intracellular Dosimetry of Inhaled Nickel by Hack, C. Eric, Covington, Tammie R., Lawrence, Greg, Shipp, Annette M., Gentry, Robinan, Yager, Janice, Clewell, Harvey J.

“…The potential associations between exposure to nickel compounds and cancer have been evaluated in both animal and epidemiological studies of occupationally…”
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Estimates of Lifetime-Absorbed Daily Doses from the Use of Personal-Care Products Containing Polyacrylamide: A Monte Carlo Analysis by Van Landingham, Cynthia B., Lawrence, Greg A, Shipp, Annette M

“…Estimates of the lifetime‐absorbed daily dose (LADD) of acrylamide resulting from use of representative personal‐care products containing polyacrylamides have…”
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Site-specific reference dose for methylmercury for fish-eating populations by Clewell, Harvey J, Crump, Kenny S, Gentry, P.Robinan, Shipp, Annette M

“…The purpose of the analysis reported here was to derive a site-specific reference dose (RfD) for methylmercury, specifically for a population exposed through…”
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Exposure assessment by George, David J., Shipp, Annette M.

“…Excipients embrace a diverse group of chemicals that are incorporated into pharmaceutical dosage forms for a variety of purposes. Typically, products contain…”
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Synthesis and antitumor activity of a series of ftorafur analogs: the effect of varying electronegativity at the 1'-position by Holshouser, Mark H, Shipp, Annette M, Ferguson, Paul W

“…To test the effect of changes in electronegativity within the alicyclic N-1 substituent 5-fluorouracil analogues on cytotoxic activity, a series of derivatives…”
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Determination of a site-specific reference dose for methylmercury for fish-eating populations by Shipp, Annette M., Gentry, P. Robinan, Lawrence, Greg, Van Landingham, Cynthia, Covington, Tammie, Clewell, Harvey J., Gribben, Kirk, Crump, Kenny

“…Environmental risk-management decisions in the U.S. involving potential exposures to methylmercury currently use a reference dose (RfD) developed by the U.S…”
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Comparison of the EU T25 Single Point Estimate Method with Benchmark Dose Response Modeling for Estimating Potency of Carcinogens by Van Landingham, Cynthia B., Allen, Bruce C., Shipp, Annette M., Crump, Kenny S.

“…The T25 single‐point estimate method of evaluating the carcinogenic potency of a chemical, which is currently used by the European Union (EU) and is denoted…”
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Influence of Prenatal Mercury Exposure Upon Scholastic and Psychologica Test Performance: Benchmark Analysis of a New Zealand Cohort by Grump, Kenny S., Kjellström, Tord, Shipp, Annette M., Silvers, Abraham, Stewart, Alistair

“…This paper presents benchmark (BMD) calculations and additional regression analyses of data from a study in which scores from 26 scholastic and psychological…”
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Correlation between carcinogenic potency of chemicals in animals and humans by Allen, B C, Crump, K S, Shipp, A M

“…Twenty-three chemicals were selected for comparison of the carcinogenic potencies estimated from epidemiological data to those estimated from animal…”
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Requirements for a Biologically Realistic Cancer Risk Assessment for Inorganic Arsenic by Clewell, Harvey J., Gentry, P. Robinan, Barton, Hugh A., Shipp, Annette M., Yager, Janice W., Andersen, Melvin E.

“…A remarkable feature of the carcinogenicity of inorganic arsenic (As,) is the observation that human exposures to Asi have been strongly associated with…”
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Cytotoxicity of three novel fluoropyrimidines in cultured L1210 murine lymphocytic leukemia cells by SHIPP, A. M, HOLSHOUSER, M. H, FERGUSON, P. W

“…Cultured L1210 murine lymphocytic leukemia cells were used to compare metabolic activation and cytotoxicity of 5-fluorouracil (FU), Ftorafur (FT), and three…”
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