Search Results - "Shiotsuka, R. N."

Three-Generation Reproductive Toxicity Study of Dietary Bisphenol A in CD Sprague-Dawley Rats by Tyl, R. W., Myers, C. B., Marr, M. C., Thomas, B. F., Keimowitz, A. R., Brine, D. R., Veselica, M. M., Fail, P. A., Chang, T. Y., Seely, J. C., Joiner, R. L., Butala, J. H., Dimond, S. S., Cagen, S. Z., Shiotsuka, R. N., Stropp, G. D., Waechter, J. M.

“…Bisphenol A (BPA) was evaluated at concentrations of 0, 0.015, 0.3, 4.5, 75, 750, and 7500 ppm (∼ 0.001, 0.02, 0.3, 5, 50, and 500 mg/kg/day of BPA)…”
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Normal reproductive organ development in CF-1 mice following prenatal exposure to bisphenol A by CAGEN, S. Z, WAECHTER, J. M, DIMOND, S. S, BRESLIN, W. J, BUTALA, J. H, JEKAT, F. W, JOINER, R. L, SHIOTSUKA, R. N, VEENSTRA, G. E, HARRIS, L. R

“…Bisphenol A (BPA) is a monomer used in the manufacture of a multitude of chemical products, including epoxy resins and polycarbonate. The objective of this…”
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Metabolism and Pharmacokinetics of Bisphenol A (BPA) and the Embryo-Fetal Distribution of BPA and BPA-Monoglucuronide in CD Sprague-Dawley Rats at Three Gestational Stages by Domoradzki, J. Y., Pottenger, L. H., Thornton, C. M., Hansen, S. C., Card, T. L., Markham, D. A., Dryzga, M. D., Shiotsuka, R. N., Waechter, J. M.

“…The pharmacokinetics of bisphenol A (BPA), including the quantification of the major BPA metabolite BPA-monoglucuronide conjugate (BPA-glucuronide) was studied…”
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Normal Reproductive Organ Development in Wistar Rats Exposed to Bisphenol A in the Drinking Water by Cagen, S.Z., Waechter, J.M., Dimond, S.S., Breslin, W.J., Butala, J.H., Jekat, F.W., Joiner, R.L., Shiotsuka, R.N., Veenstra, G.E., Harris, L.R.

“…Bisphenol A (BPA) is a chemical used primarily as a monomer in the manufacture of numerous chemical products, such as epoxy resins and polycarbonate. The…”
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Age and Dose Dependency of the Pharmacokinetics and Metabolism of Bisphenol A in Neonatal Sprague-Dawley Rats Following Oral Administration by Domoradzki, J. Y., Thornton, C. M., Pottenger, L. H., Hansen, S. C., Card, T. L., Markham, D. A., Dryzga, M. D., Shiotsuka, R. N., Waechter, J. M.

“…Previous studies demonstrated the rapid clearance of bisphenol A (BPA) from blood following oral administration to adult rats with the principal metabolite…”
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A combined reproduction, neonatal development, and neurotoxicity study with 1,6-hexamethylene diisocyanate (HDI) in the rat by Astroff, A.B, Sheets, L.P, Sturdivant, D.W, Stuart, B.P, Shiotsuka, R.N, Simon, G.S, Andrews, L.S

“…1,6-Hexamethylene diisocyanate (HDI), a chemical widely used in commercial polyurethane products, was evaluated in a combined…”
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A COMPARATIVE RESPIRATORY SENSITIZATION STUDY OF 2,4- AND 2,6-TOLUENE DIISOCYANATE USING GUINEA PIGS by Shiotsuka, R N, Warren, D L, Halliburton, A T, Sturdivant, D W

“…The potential exposure of workers to both 2,4-toluene diisocyanate (2,4-TDI) and 2,6-TDI led to an investigation of the comparative respiratory sensitization…”
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Carbon monoxide enhances development of hypertension in Dahl rats by Shiotsuka, R N, Drew, R T, Wehner, R W

“…The influence of carbon monoxide (CO) on the development of systemic hypertension was studied in Dahl rats selectively bred for susceptibility (DS) and…”
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Pulmonary changes resulting from subchronic exposure to cadmium chloride aerosol by Kutzman, R S, Drew, R T, Shiotsuka, R N, Cockrell, B Y

“…Fischer-344 rats were exposed to 0.0, 0.3, 1.0, or 2.0 mg Cd/m3 as CdCl2 aerosol for 6 h/d, 5 d/wk, for 62 exposure days. Exposure to 2.0 mg Cd/m3 resulted in…”
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Method of measuring deposition of unlabeled monodisperse microspheres in rat lungs by Shiotsuka, R N, Costa, D L, Osheroff, M R, Drew, R T

“…A system to simultaneously measure the total deposition of four different sizes of monodisperse microspheres in normal and damaged lungs of rats was developed…”
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Use of fluidizing bed aerosol generators to establish a dust mixture of two substances at a fixed ratio for inhalation toxicity studies by Shiotsuka, R N, Kutzman, R S, Firriolo, J M, Drew, R T

“…A method was developed to use two fluidizing bed generators to deliver a mixture of 1 mg cobalt + 15 mg tungsten carbide/m3 to an inhalation exposure chamber…”
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Toxicity of calcium sodium metaphosphate fiber. I. In vitro and in vivo degradation and clearance studies by Nair, R S, Li, A P, Shiotsuka, R N, Wilson, A G

“…In an experiment to ascertain the degradability of calcium sodium metaphosphate (CSM) fiber in vitro, 32P-labeled CSM fiber was incubated in media with or…”
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The combination of ozone and silica on the development of pulmonary fibrosis by Shiotsuka, R N, Yermakoff, J K, Osheroff, M R, Drew, R T

“…The biologic interactions of potentially fibrogenic agents commonly occurring as environmental pollutants remain to be rigorously characterized. Two agents…”
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Circadian susceptibility rhythm of the rat to alloxan by Hernandez, R E, Kühl, J F, Halberg, E, Halberg, F, Shiotsuka, R N, Haus, E

“…The susceptibility of rats to alloxan undergoes a circadin rhythm. The toxicity rhythm, presumably involving injury to liver, kidney and other sites,…”
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Developmental Neurotoxicity Study of Dietary Bisphenol A in Sprague-Dawley Rats by Stump, Donald G., Beck, Melissa J., Radovsky, Ann, Garman, Robert H., Freshwater, Lester L., Sheets, Larry P., Marty, M. Sue, Waechter, John M., Dimond, Stephen S., Van Miller, John P., Shiotsuka, Ronald N., Beyer, Dieter, Chappelle, Anne H., Hentges, Steven G.

“…This study was conducted to determine the potential of bisphenol A (BPA) to induce functional and/or morphological effects to the nervous system of F1…”
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Developmental toxicity of 1,6-hexamethylene diisocyanate (HDI) in the Sprague-Dawley rat by Astroff, A. Barry, Sturdivant, David W., Lake, Stephen G., Shiotsuka, Ronald N., Simon, Glenn S., Andrews, Larry S.

“…Background 1,6‐Hexamethylene diisocyanate (HDI), a widely used chemical in commercial polyurethane manufacture, has been shown to affect the respiratory tract…”
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Normal reproductive organ development in wistar rats exposed to bisphenol A in the drinking water by Cagen, S Z, Waechter, J M, Dimond, S S, Breslin, W J, Butala, J H, Jekat, F W, Joiner, R L, Shiotsuka, R N, Veenstra, GE, Harris, L R

“…The objective of the research was to study the effects of bisphenol A (BPA) on the sexual development of male rats and in particular to confirm previously…”
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Increased Tolerance of Leukemic Mice to Arabinosyl Cytosine with Schedule Adjusted to Circadian System by Haus, Erhard, Halberg, Franz, Scheving, Lawrence E., Pauly, John E., Cardoso, Sergio, Jürgen F. W. Kühl, Sothern, Robert B., Shiotsuka, Ronald N., Hwang, Dar Shong

“…Mice (BDF$_{1}$) inoculated with L1210 leukemia survive for a statistically significantly longer span when four courses of arabinosyl cytosine are administered…”
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