Search Results - "Shiomi, Tetsuya"

Fatal Disseminated Tuberculosis and Concurrent Disseminated Cryptococcosis in a Ruxolitinib-treated Patient with Primary Myelofibrosis: A Case Report and Literature Review by Ogai, Asuka, Yagi, Kazuma, Ito, Fumimaro, Domoto, Hideharu, Shiomi, Tetsuya, Chin, Kenko

“…Ruxolitinib, a Janus kinase inhibitor, improves symptoms in patients with myelofibrosis. However, its association with the development of opportunistic…”
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Cyclopolymerization of a bisacrylate through selective formation of a 19-membered ring by Ochiai, Bungo, Shiomi, Tetsuya, Yoshita, Hasumi

“…Radical polymerization of a bisacrylate monomer trans -1,2-bisacryloyloxyethylcarbamoyloxycyclohexane proceeded via cyclopolymerization. The repeating unit…”
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Resolution of a left ventricular thrombus by the thrombolytic action of dabigatran by Nagamoto, Yasutsugu, Shiomi, Tetsuya, Matsuura, Taku, Okahara, Arihide, Takegami, Kaoru, Mine, Daigo, Shirahama, Takaharu, Koga, Yasuaki, Yoshida, Keiki, Sadamatsu, Kenji, Hayashida, Kiyoshi

“…A 77-year-old man was referred to our cardiovascular department for detailed examination after abnormal electrocardiography findings were obtained during a…”
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Targeted deletion of MMP-2 attenuates early LV rupture and late remodeling after experimental myocardial infarction by Hayashidani, Shunji, Tsutsui, Hiroyuki, Ikeuchi, Masaki, Shiomi, Tetsuya, Matsusaka, Hidenori, Kubota, Toru, Imanaka-Yoshida, Kyoko, Itoh, Takeshi, Takeshita, Akira

“…Matrix metalloproteinase-2 (MMP-2) is prominently overexpressed both after myocardial infarction (MI) and in heart failure. However, its pathophysiological…”
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Cluster analysis of long COVID in Japan and association of its trajectory of symptoms and quality of life by Ito, Fumimaro, Terai, Hideki, Kondo, Masahiro, Takemura, Ryo, Namkoong, Ho, Asakura, Takanori, Chubachi, Shotaro, Masuzawa, Keita, Nakayama, Sohei, Suzuki, Yusuke, Hashiguchi, Mizuha, Kagyo, Junko, Shiomi, Tetsuya, Minematsu, Naoto, Manabe, Tadashi, Fukui, Takahiro, Funatsu, Yohei, Koh, Hidefumi, Masaki, Katsunori, Ohgino, Keiko, Miyata, Jun, Kawada, Ichiro, Ishii, Makoto, Sato, Yasunori, Fukunaga, Koichi

“…BackgroundMultiple prolonged symptoms observed in patients who recovered from COVID-19 are defined as long COVID. Although diverse phenotypic combinations are…”
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Overexpression of glutathione peroxidase prevents left ventricular remodeling and failure after myocardial infarction in mice by SHIOMI, Tetsuya, TSUTSUI, Hiroyuki, MATSUSAKA, Hidenori, MURAKAMI, Kimiyo, HAYASHIDANI, Shunji, IKEUCHI, Masaki, JING WEN, KUBOTA, Toru, UTSUMI, Hideo, TAKESHITA, Akira

“…Oxidative stress plays an important role in the pathophysiology of heart failure. We determined whether the overexpression of glutathione peroxidase (GSHPx)…”
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Successful Tepotinib Challenge After Capmatinib-Induced Interstitial Lung Disease in a Patient With Lung Adenocarcinoma Harboring MET Exon 14 Skipping Mutation: Case Report by Hashiguchi, Mizuha Haraguchi, Sato, Takashi, Yamamoto, Hiroki, Watanabe, Rinako, Kagyo, Junko, Domoto, Hideharu, Shiomi, Tetsuya

“…MET tyrosine kinase inhibitors, capmatinib and tepotinib, have been recently introduced for the treatment of advanced NSCLC with MET exon 14 skipping…”
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Anti-monocyte chemoattractant protein-1 gene therapy attenuates left ventricular remodeling and failure after experimental myocardial infarction by HAYASHIDANI, Shunji, TSUTSUI, Hiroyuki, SHIOMI, Tetsuya, IKEUCHI, Masaki, MATSUSAKA, Hidenori, SUEMATSU, Nobuhiro, JING WEN, EGASHIRA, Kensuke, TAKESHITA, Akira

“…Increased expression of monocyte chemoattractant protein-1 (MCP-1) has recently been described in clinical and experimental failing heart. However, its…”
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Induction of mucin and MUC5AC expression by the protease activity of Aspergillus fumigatus in airway epithelial cells by Oguma, Tsuyoshi, Asano, Koichiro, Tomomatsu, Katsuyoshi, Kodama, Motohiro, Fukunaga, Koichi, Shiomi, Tetsuya, Ohmori, Nao, Ueda, Soichiro, Takihara, Takahisa, Shiraishi, Yoshiki, Sayama, Koichi, Kagawa, Shizuko, Natori, Yukikazu, Lilly, Craig M, Satoh, Kazuo, Makimura, Koichi, Ishizaka, Akitoshi

“…Allergic bronchopulmonary mycosis, characterized by excessive mucus secretion, airflow limitation, bronchiectasis, and peripheral blood eosinophilia, is…”
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Fluvastatin, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, attenuates left ventricular remodeling and failure after experimental myocardial infarction by HAYASHIDANI, Shunji, TSUTSUI, Hiroyuki, SHIOMI, Tetsuya, SUEMATSU, Nobuhiro, KINUGAWA, Shintaro, IDE, Tomomi, JING WEN, TAKESHITA, Akira

“…Short-term administration of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, statins, has been shown to attenuate ischemia-reperfusion…”
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Standard therapy‑resistant small cell lung cancer showing dynamic transition of neuroendocrine fate during the cancer trajectory: A case report by Ito, Fumimaro, Sato, Takashi, Emoto, Katsura, Kaizuka, Nobuki, Yagi, Kazuma, Watanabe, Rinako, Hashiguchi, Mizuha Haraguchi, Ninomiya, Hironori, Ikematsu, Yuki, Tanaka, Kentaro, Domoto, Hideharu, Shiomi, Tetsuya

“…While small cell lung cancer (SCLC) has been treated as a single disease historically, recent studies have suggested that SCLC can be classified into molecular…”
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A case of lung adenocarcinoma with a novel CD74‐ROS1 fusion variant identified by comprehensive genomic profiling that responded to crizotinib and entrectinib by Hashiguchi, Mizuha Haraguchi, Sato, Takashi, Watanabe, Rinako, Kagyo, Junko, Matsuzaki, Tomohiko, Domoto, Hideharu, Kato, Terufumi, Nakahara, Yoshiro, Yokose, Tomoyuki, Hiroshima, Yukihiko, Shiomi, Tetsuya

“…ROS1 rearrangements are found in 1–2% of patients with non‐small‐cell lung cancer. The detection of the rearrangements is crucial since clinically effective…”
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Human neutrophil elastase-mediated goblet cell metaplasia is attenuated in TACE-deficient mice by Park, Jin-Ah, Sharif, Asma S, Shiomi, Tetsuya, Kobzik, Lester, Kasahara, David I, Tschumperlin, Daniel J, Voynow, Judith, Drazen, Jeffrey M

“…Neutrophilic inflammation is associated with chronic airway diseases. It has been observed that human neutrophil elastase (HNE), which is secreted by active…”
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Longitudinal long COVID symptoms in Japanese patients after COVID-19 vaccinations by Nakagawara, Kensuke, Morita, Atsuho, Namkoong, Ho, Terai, Hideki, Chubachi, Shotaro, Asakura, Takanori, Tanaka, Hiromu, Ito, Fumimaro, Matsuyama, Emiko, Kaji, Masanori, Saito, Ayaka, Takaoka, Hatsuyo, Okada, Masahiko, Sunata, Keeya, Watase, Mayuko, Yagi, Kazuma, Ohgino, Keiko, Miyata, Jun, Kamata, Hirofumi, Kawada, Ichiro, Kobayashi, Keigo, Hirano, Toshiyuki, Inoue, Takashi, Kagyo, Junko, Shiomi, Tetsuya, Otsuka, Kengo, Miyao, Naoki, Odani, Toshio, Baba, Rie, Arai, Daisuke, Nakachi, Ichiro, Ueda, Soichiro, Funatsu, Yohei, Koh, Hidefumi, Ishioka, Kota, Takahashi, Saeko, Nakamura, Morio, Sato, Toshiro, Hasegawa, Naoki, Kitagawa, Yuko, Kanai, Takanori, Ishii, Makoto, Fukunaga, Koichi

“…•Some Japanese patients with long COVID had improved symptoms after vaccination.•Symptoms that improved varied and included dyspnea, alopecia, and…”
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Cyclooxygenase-2/Prostaglandin D2/CRTH2 Pathway Mediates Double-Stranded RNA-Induced Enhancement of Allergic Airway Inflammation by Shiraishi, Yoshiki, Asano, Koichiro, Niimi, Kyoko, Fukunaga, Koichi, Wakaki, Misa, Kagyo, Junko, Takihara, Takahisa, Ueda, Soichiro, Nakajima, Takeshi, Oguma, Tsuyoshi, Suzuki, Yusuke, Shiomi, Tetsuya, Sayama, Koichi, Kagawa, Shizuko, Ikeda, Eiji, Hirai, Hiroyuki, Nagata, Kinya, Nakamura, Masataka, Miyasho, Taku, Ishizaka, Akitoshi

“…Respiratory RNA viruses responsible for the common cold often worsen airway inflammation and bronchial responsiveness, two characteristic features of human…”
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Prostaglandin D2-induced eosinophilic airway inflammation is mediated by CRTH2 receptor by Shiraishi, Yoshiki, Asano, Koichiro, Nakajima, Takeshi, Oguma, Tsuyoshi, Suzuki, Yusuke, Shiomi, Tetsuya, Sayama, Koichi, Niimi, Kyoko, Wakaki, Misa, Kagyo, Junko, Ikeda, Eiji, Hirai, Hiroyuki, Yamaguchi, Kazuhiro, Ishizaka, Akitoshi

“…Mast cell-derived prostaglandin D(2) (PGD(2)) is one of the essential modulators of eosinophilic airway inflammation in asthma and allergic rhinitis. Two G…”
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Streptozotocin-induced hyperglycemia exacerbates left ventricular remodeling and failure after experimental myocardial infarction by Shiomi, Tetsuya, Tsutsui, Hiroyuki, Ikeuchi, Masaki, Matsusaka, Hidenori, Hayashidani, Shunji, Suematsu, Nobuhiro, Wen, Jing, Kubota, Toru, Takeshita, Akira

“…The aim of the present study was to determine whether streptozotocin (STZ)-induced hyperglycemia exacerbates progressive left ventricular (LV) dilation and…”
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Lysophosphatidic acid stimulates epidermal growth factor-family ectodomain shedding and paracrine signaling from human lung fibroblasts by Shiomi, Tetsuya, Boudreault, Francis, Padem, Nurcicek, Higashiyama, Shigeki, Drazen, Jeffrey M., Tschumperlin, Daniel J.

“…ABSTRACT Lysophospatidic acid (LPA) is a bioactive lipid mediator implicated in tissue repair and wound healing. It mediates diverse functional effects in…”
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Enhanced generation of reactive oxygen species in the limb skeletal muscles from a murine infarct model of heart failure by TSUTSUI, Hiroyuki, IDE, Tomomi, HAYASHIDANI, Shunji, SUEMATSU, Nobuhiro, SHIOMI, Tetsuya, JING WEN, NAKAMURA, Kei-Ichiro, ICHIKAWA, Kazuhiro, UTSUMI, Hideo, TAKESHITA, Akira

“…The generation of reactive oxygen species (ROS) is enhanced in the failing myocardium. We hypothesized that ROS were also increased in the limb skeletal…”
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Longitudinal follow-up study of smoking-induced lung density changes by high-resolution computed tomography by SOEJIMA, K, YAMAGUCHI, K, TATENO, H, SHIOMI, T, KOHDA, E, TAKESHITA, K, ITO, Y, MASTUBARA, H, OGUMA, T, INOUE, T, OKUBO, Y, AMAKAWA, K

“…To evaluate the ability of high-resolution computed tomography (HRCT) to detect longitudinal changes in structural abnormalities caused by smoking, HRCT and…”
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