Search Results - "Shioi, J"
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Identification and neuron specific expression of the S182/presenilin I protein in human and rodent brains
Published in Journal of neuroscience research (01-08-1996)“…Many individuals with familial Alzheimer disease (FAD) have mutations in a gene termed S182 or presenilin I (PS‐I). Currently, the PS‐I gene product has not…”
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Evidence for intracellular cleavage of the Alzheimer's amyloid precursor in PC12 cells
Published in Journal of neuroscience research (01-10-1992)“…The Alzheimer's amyloid precursor (APP) is cleaved by an unidentified enzyme (APP secretase) to produce soluble APP. Fractionation of PC12 cell homogenates in…”
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Presenilin-1-immunoreactive neurons are preserved in late-onset Alzheimer's disease
Published in The American journal of pathology (01-02-1997)“…Recent studies have suggested that missense mutations in the presenilin-1 gene are causally related to the majority of familial early-onset Alzheimer's disease…”
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Artificially imposed electrical potentials drive L-glutamate uptake into synaptic vesicles of bovine cerebral cortex
Published in Biochemical journal (01-04-1990)“…L-Glutamate is a major excitatory neurotransmitter in the central nervous system. MgATP-dependent glutamate uptake and H(+)-pumping ATPase activity were…”
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Chondroitin sulfate proteoglycan form of the Alzheimer's beta-amyloid precursor
Published in The Journal of biological chemistry (15-07-1992)“…The Alzheimer's amyloid beta protein is derived from a family of membrane glycoproteins termed amyloid precursor proteins (APP). Here we show that APP exists…”
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A presenilin-1/γ-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions
Published in The EMBO journal (15-04-2002)“…E‐cadherin controls a wide array of cellular behaviors including cell–cell adhesion, differentiation and tissue development. Here we show that presenilin‐1…”
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Interaction of calcium with porcine adrenal chromogranin A (secretory protein-I) and chromogranin B (secretogranin I)
Published in The American journal of physiology (01-08-1989)“…Secretory granules of endocrine cells contain one or more of the acidic secretory proteins chromogranin A (secretory protein-I), chromogranin B (secretogranin…”
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Glutamate uptake into synaptic vesicles of bovine cerebral cortex and electrochemical potential difference of proton across the membrane
Published in Biochemical journal (01-03-1989)“…Measurements have been made of the ATP-dependent membrane potential (delta psi) and pH gradient (delta pH) across the membranes of the synaptic vesicles…”
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PS1 activates PI3K thus inhibiting GSK-3 activity and tau overphosphorylation: effects of FAD mutations
Published in The EMBO journal (07-07-2004)“…Phosphatidylinositol 3‐kinase (PI3K) promotes cell survival and communication by activating its downstream effector Akt kinase. Here we show that PS1, a…”
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Quantitative measurements of proton motive force and motility in Bacillus subtilis
Published in Journal of Bacteriology (01-12-1980)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Oxygen as attractant and repellent in bacterial chemotaxis
Published in Journal of Bacteriology (01-07-1987)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Signal transduction in chemotaxis to oxygen in Escherichia coli and Salmonella typhimurium
Published in Journal of Bacteriology (01-12-1988)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Oxygen taxis and proton motive force in Salmonella typhimurium
Published in The Journal of biological chemistry (10-09-1984)“…The aerotactic response of Salmonella typhimurium SL3730 has been quantitatively correlated with a change in the proton motive force (delta p) as measured by a…”
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Effect of temperature on motility and chemotaxis of Escherichia coli
Published in Journal of Bacteriology (01-09-1976)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Cyclooxygenase (COX)-2 and COX-1 Potentiate β-Amyloid Peptide Generation through Mechanisms That Involve γ-Secretase Activity
Published in The Journal of biological chemistry (19-12-2003)“…In previous studies we found that overexpression of the inducible form of cyclooxygenase, COX-2, in the brain exacerbated β-amyloid (Aβ) neuropathology in a…”
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Identification of a site of ATP requirement for signal processing in bacterial chemotaxis
Published in Journal of Bacteriology (01-06-1988)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Requirement of ATP in bacterial chemotaxis
Published in The Journal of biological chemistry (25-07-1982)“…Evidence is presented that chemotaxis requires ATP or a closely related metabolite, in addition to its known requirements of ATP for synthesis of…”
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Presenilin-1 Binds Cytoplasmic Epithelial Cadherin, Inhibits Cadherin/p120 Association, and Regulates Stability and Function of the Cadherin/Catenin Adhesion Complex
Published in Proceedings of the National Academy of Sciences - PNAS (27-02-2001)“…Here we show that presenilin-1 (PS1), a protein involved in Alzheimer's disease, binds directly to epithelial cadherin (E-cadherin). This binding is mediated…”
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Presenilin-1 Forms Complexes with the Cadherin/Catenin Cell–Cell Adhesion System and Is Recruited to Intercellular and Synaptic Contacts
Published in Molecular cell (01-12-1999)“…In MDCK cells, presenilin-1 (PS1) accumulates at intercellular contacts where it colocalizes with components of the cadherin-based adherens junctions. PS1…”
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