Search Results - "Shintaro Ide"

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    Sertoli cell ablation and replacement of the spermatogonial niche in mouse by Yokonishi, Tetsuhiro, McKey, Jennifer, Ide, Shintaro, Capel, Blanche

    Published in Nature communications (02-01-2020)
    “…Spermatogonia, which produce sperm throughout the male lifetime, are regulated inside a niche composed of Sertoli cells, and other testis cell types. Defects…”
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    Journal Article
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    Ferroptotic stress promotes the accumulation of pro-inflammatory proximal tubular cells in maladaptive renal repair by Ide, Shintaro, Kobayashi, Yoshihiko, Ide, Kana, Strausser, Sarah A, Abe, Koki, Herbek, Savannah, O'Brien, Lori L, Crowley, Steven D, Barisoni, Laura, Tata, Aleksandra, Tata, Purushothama Rao, Souma, Tomokazu

    Published in eLife (19-07-2021)
    “…Overwhelming lipid peroxidation induces ferroptotic stress and ferroptosis, a non-apoptotic form of regulated cell death that has been implicated in…”
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    Yolk-sac-derived macrophages progressively expand in the mouse kidney with age by Ide, Shintaro, Yahara, Yasuhito, Kobayashi, Yoshihiko, Strausser, Sarah A, Ide, Kana, Watwe, Anisha, Xu-Vanpala, Shengjie, Privratsky, Jamie R, Crowley, Steven D, Shinohara, Mari L, Alman, Benjamin A, Souma, Tomokazu

    Published in eLife (17-04-2020)
    “…Renal macrophages represent a highly heterogeneous and specialized population of myeloid cells with mixed developmental origins from the yolk-sac and…”
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    Twist1 in podocytes ameliorates podocyte injury and proteinuria by limiting CCL2-dependent macrophage infiltration by Ren, Jiafa, Xu, Yuemei, Lu, Xiaohan, Wang, Liming, Ide, Shintaro, Hall, Gentzon, Souma, Tomokazu, Privratsky, Jamie R, Spurney, Robert F, Crowley, Steven D

    Published in JCI insight (09-08-2021)
    “…The transcription factor Twist1 regulates several processes that could impact kidney disease progression, including epithelial cell differentiation and…”
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    A macrophage-endothelial immunoregulatory axis ameliorates septic acute kidney injury by Privratsky, Jamie R, Ide, Shintaro, Chen, Yanting, Kitai, Hiroki, Ren, Jiafa, Fradin, Helene, Lu, Xiaohan, Souma, Tomokazu, Crowley, Steven D

    Published in Kidney international (01-03-2023)
    “…The most common cause of acute kidney injury (AKI) in critically ill patients is sepsis. Kidney macrophages consist of both F4/80 and CD11b cells. The role of…”
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    Type 1 Angiotensin Receptors on CD11c-Expressing Cells Protect Against Hypertension by Regulating Dendritic Cell–Mediated T Cell Activation by Lu, Xiaohan, Zhang, Jiandong, Wen, Yi, Ren, Jiafa, Griffiths, Robert, Rudemiller, Nathan P., Ide, Shintaro, Souma, Tomokazu, Crowley, Steven D.

    Published in Hypertension (Dallas, Tex. 1979) (01-06-2022)
    “…Type 1 angiotensin (AT ) receptors are expressed on immune cells, and we previously found that bone marrow-derived AT receptors protect against Ang…”
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    Sex differences in resilience to ferroptosis underlie sexual dimorphism in kidney injury and repair by Ide, Shintaro, Ide, Kana, Abe, Koki, Kobayashi, Yoshihiko, Kitai, Hiroki, McKey, Jennifer, Strausser, Sarah A., O’Brien, Lori L., Tata, Aleksandra, Tata, Purushothama Rao, Souma, Tomokazu

    Published in Cell reports (Cambridge) (08-11-2022)
    “…In both humans and mice, repair of acute kidney injury is worse in males than in females. Here, we provide evidence that this sexual dimorphism results from…”
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