Search Results - "Shinozuka, Takuma"

Wnt produced by stretched roof-plate cells is required for the promotion of cell proliferation around the central canal of the spinal cord by Shinozuka, Takuma, Takada, Ritsuko, Yoshida, Shosei, Yonemura, Shigenobu, Takada, Shinji

“…Cell morphology changes dynamically during embryogenesis, and these changes create new interactions with surrounding cells, some of which are presumably…”
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Manipulation of Signal Gradient and Transcription Factors Recapitulates: Multiple Hypothalamic Identities by Yamamoto, Maho, Ong, Agnes Lee Chen, Shinozuka, Takuma, Shirai, Manabu, Sasai, Noriaki

“…Abstract During development, the hypothalamus emerges from the ventral diencephalon and is regionalized into several distinct functional domains. Each domain…”
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Differences in the secretion and transport of Wnt proteins by Takada, Shinji, Fujimori, Sayumi, Shinozuka, Takuma, Takada, Ritsuko, Mii, Yusuke

“…During the last three decades, our understanding about Wnt signaling has progressed greatly, especially with regards to the molecular mechanism of…”
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Intercellular exchange of Wnt ligands reduces cell population heterogeneity during embryogenesis by Hatakeyama, Yudai, Saito, Nen, Mii, Yusuke, Takada, Ritsuko, Shinozuka, Takuma, Takemoto, Tatsuya, Naoki, Honda, Takada, Shinji

“…Wnt signaling is required to maintain bipotent progenitors for neural and paraxial mesoderm cells, the neuromesodermal progenitor (NMP) cells that reside in…”
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Morphological and Functional Changes of Roof Plate Cells in Spinal Cord Development by Shinozuka, Takuma, Takada, Shinji

“…The most dorsal region, or roof plate, is the dorsal organizing center of developing spinal cord. This region is also involved in development of neural crest…”
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Acquisition of neural fate by combination of BMP blockade and chromatin modification by Ong, Agnes Lee Chen, Kokaji, Toshiya, Kishi, Arisa, Takihara, Yoshihiro, Shinozuka, Takuma, Shimamoto, Ren, Isotani, Ayako, Shirai, Manabu, Sasai, Noriaki

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Acquisition of neural fate by combination of BMP blockade and chromatin modification by Ong, Agnes Lee Chen, Kokaji, Toshiya, Kishi, Arisa, Takihara, Yoshihiro, Shinozuka, Takuma, Shimamoto, Ren, Isotani, Ayako, Shirai, Manabu, Sasai, Noriaki

“…Neural induction is a process where naive cells are converted into committed cells with neural characteristics, and it occurs at the earliest step during…”
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Androgen receptor of the frog Rana rugosa: molecular cloning and its characterization by Yokoyama, Satoshi, Oshima, Yuki, Tokita, Junpei, Suda, Mari, Shinozuka, Takuma, Nakamura, Masahisa

“…The androgen receptor(AR) gene is located on the Z and W sex chromosomes in the frog Rana rugosa, designated Z‐ and W‐AR, respectively. Among various tissues…”
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Regulation of progenitor cell survival by a novel chromatin remodeling factor during neural tube development by Sasai, Noriaki, Tada, Shogo, Ohshiro, Jumi, Kogiso, Chikara, Shinozuka, Takuma

“…During development, progenitor cell survival is essential for proper tissue functions, but the underlying mechanisms are not fully understood. Here we show…”
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Rspo1 and Rspo3 are required for sensory lineage neural crest formation in mouse embryos by Shinozuka, Takuma, Aoki, Motoko, Hatakeyama, Yudai, Sasai, Noriaki, Okamoto, Hitoshi, Takada, Shinji

“…Background R‐spondins (Rspos) are secreted proteins that modulate Wnt/β‐catenin signaling. At the early stages of spinal cord development, Wnts (Wnt1, Wnt3a)…”
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Combination of blockade of endothelin signalling and compensation of IGF1 expression protects the retina from degeneration by Shigesada, Naoya, Shikada, Naoya, Shirai, Manabu, Toriyama, Michinori, Higashijima, Fumiaki, Kimura, Kazuhiro, Kondo, Toru, Bessho, Yasumasa, Shinozuka, Takuma, Sasai, Noriaki

“…Retinitis pigmentosa (RP) and macular dystrophy (MD) cause severe retinal dysfunction, affecting 1 in 4000 people worldwide. This disease is currently assumed…”
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The Rx transcription factor is required for determination of the retinal lineage and regulates the timing of neuronal differentiation by Yamamoto, Maho, Ong, Agnes Lee Chen, Shinozuka, Takuma, Sasai, Noriaki

“…Understanding the molecular mechanisms leading to retinal development is of great interest for both basic scientific and clinical applications. Several…”
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Erratum: Acquisition of neural fate by combination of BMP blockade and chromatin modification by Ong, Agnes Lee Chen, Kokaji, Toshiya, Kishi, Arisa, Takihara, Yoshihiro, Shinozuka, Takuma, Shimamoto, Ren, Isotani, Ayako, Shirai, Manabu, Sasai, Noriaki

“…[This corrects the article DOI: 10.1016/j.isci.2023.107887.]…”
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Wnt signal modulates proliferation of spinal cord ependymal cells by promoting morphological change of the source cells by Shinozuka, Takuma, Takada, Ritsuko, Takada, Shinji

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